... These clinical and basic science studies therefore suggest that P4 might be useful as an adjunct treatment for ovarian cancer. In fact one study using a xenograph ovarian tumor model has shown that high doses of P4 enhance the apoptotic action of cisplatin [5], which is consistent with a very limited clinical trial data [6]. Unfortunately other trials in both animal and humans have been relatively unsuccessful (See review by Ho [2]). ...
Objective: The transcription factor Snail, which is implicated in the triggering of epithelial-mesenchymal transitions (EMT), plays an important role in adhesion, invasion and metastasis of tumor cells. In the present study, we assessed 17beta-Estradiol (E2)'s effect on Snail, E-cadherin and MMP-2 expression of epithelial ovarian cancer cell line...
School of Mathematical Sciences The School of Mathematical Sciences (SMS) enjoys a rich history dating back to the establishment of Department of Mathematics in 1928, 32 years after the founding of the university. One evidence of its place in modern mathematics in China is that the first Congress of the Chinese Mathematical Society was held in 1935 at SJTU. In 2014, the Department of Mathematics was selected by the central government as one of the first four Model Schools for Internationalization, which encourages us to be more internationalization in its practices, vision and outlook. With the growth in size, it was reorganized into the School of Mathematical Sciences in December 2015. With more than 100 faculties members, the school now consists of 3 departments (Mathematics, Applied and Computational Mathematics, and Statistics) and 1 center (Research Center for Mathematics Education).
Luteinizing hormone (LH) plays an important role in the development of ovarian cancer, and has been shown to inhibit apoptosis in ovarian cancer cells. Similarly, survivin is a molecule that has been shown to inhibit apoptosis in other types of cancer. Therefore, the aim of this study was to determine whether survivin can be induced by LH in ovaria...
Ovarian clear cell adenocarcinoma (OCCA) is an aggressive ovarian malignancy with a poor prognosis. The role of estrogen receptor β (ERβ) in the development of OCCA remains to be clarified. To investigate the action of ERβ in the proliferation and invasion of OCCA cells, the ES-2 cell line was stably transfected with full-length human ERβ cDNA, and...
Objective To assess the effect of 17β-estradiol(E2) on cell proliferation, cell invasiveness and its regulation of MTA3, Snail and matrix metalloproteinase 2 (MMP-2) expression in the ovarian clear cell adenocarcinoma cell line ES2, and to further investigate the mechanism involved. Methods We first investigated expression of ERα, ERβ, PR and E-cad...
... Mediator complex subunit 19 (MED19) is a member of the mediator that has a key role in the activation and repression of signal transduction or the regulation of transcription in carcinomas ( Casamassimi and Napoli, 2007;Sun et al, 2011). Accumulating evidence has shown that MED19 has important roles in cancer cell proliferation and tumorigenesis, and suppression of MED19 expression induces inhibition of cell proliferation and tumorigenesis in several different tumour types including lung cancer, pancreatic cancer, ovarian cancer and breast cancer ( Liu et al, 2012;Wei et al, 2015). Then we speculated that miR-214 played tumorigenic role by its target MED19 in CRC. ...
To compare the therapeutic and toxic profile of topotecan given intraperitoneally with intravenously in human ovarian cancer xenografted into athymic nude mice. Eighty female Balb-c/nu-nu mice were randomized assigned into eight groups (n=10). Xenografts resulted from intramesentery injection of cultured human ovarian cancer cells SKOV3 in athymic...
Aim: To assess the clinical significance of hTERC amplification for cervical cancer screening detected by fluorescence in situ hybridization (FISH) and compare it with that of current screening methods within the same group. Methods: A total of one hundred and nine women were recruited in this study. All of them had liquid-based thin-prep cytologic...

Sun Min, wife of a Chinese businessman, was found guilty of insider trading in Huiyuan shares by the Market Misconduct Tribunal in Hong Kong. The businessman, Mo Feng, and Sun purchased 8.61 million shares in the company between 30 July and 29 August 2008, at between HK$3.78 and 4.66 (US$0.48–$0.60), then resold their shares HK$10.24–$11.12 (US$1.21–$1.43) each on 3–4 Sept. 2008, after Huiyuan's stock price had surged after the proposed takeover was announced. A profit of HK$55.1 million (US$7.09 million) was made from the trade.[9] Sun was convicted of having dealt in 3.13 million Huiyuan shares in August 2008[10] and was fined HK$20 million (US$2.56 million), the largest ever imposed for the crime in the territory.[11]


China-UK Low Carbon College China-UK Low Carbon College was established in May, 2017, thanks to the joint efforts of Shanghai Jiao Tong University, the University of Edinburgh and other UK universities, as well as Shanghai and Lingang government. As the first domestic low carbon college (LCC), the LCC aims to become a world-class innovative higher education and research institution with international influence, which provides academic programs, executive training, scientific research and industrial incubation. Green low-carbon development is an inevitable choice for China and the rest of the world to deal with global warming, a challenge that the whole world is facing. The college will concentrate on green development strategy, and carry out teaching and research on low-carbon energy, low-carbon environment, carbon finance, carbon management and low-carbon city etc. The goal of the LCC is to serve as a cradle of talents for low carbon industries and to support the development of low carbon fields with cutting-edge technologies. With the support from people in all walks of life, we are determined to develop the college as a first-class, industry-oriented and discipline-based institution. We strongly welcome the talents around the world who are interested in low carbon fields to join our college.
To make the competition for his daughter's hand-in-marriage a fair one, Huang Yaoshi sets a series of three tests for the two contestants: Guo Jing and Ouyang Ke. The first obstacle is a test of martial arts. Ouyang Feng spars with Guo Jing while Hong Qigong fights Ouyang Ke. Guo Jing wins the first bout but ties with Ouyang Ke in the subsequent round, which involves appreciation of a piece of music played by Huang Yaoshi. The last assessment is a test of memory, in which Huang Yaoshi produces an incomplete copy of the Nine Yin Manual, without identifying the book, and asks the two contestants to memorise the text and recite to him later. Guo Jing read the manual before so he recites fluently and defeats Ouyang Ke.

Shortly after his marriage to Feng Heng, Huang Yaoshi met Wang Chongyang's junior, Zhou Botong. He learnt from Zhou Botong that Wang Chongyang had died and that Zhou had inherited the Nine Yin Manual. He wanted the book for himself so he tricked Zhou Botong into allowing his wife to read it. Zhou Botong agreed and let her read the second volume of the manual. Feng Heng had eidetic memory so she memorised the book easily. She lied to Zhou Botong that the manual was fake and that it was actually a copy of a book of childish rites she had memorised by heart. She recited the first few verses of the manual verbatim to Zhou Botong, who mistakenly believed her and destroyed the book in anger. After Zhou Botong left, Feng Heng wrote a copy of the manual from memory for her husband.
Human embryonic stem (hES) cells are able to give rise to a variety of cell lineages under specific culture condition. An effective strategy for stable genetic modification in hES cells may provide a powerful tool for study of human embryogenesis and cell-based therapies. However, gene silences are documented in hES cells. In current study, we inve...
Objective: This research was carried out to investigate the effectiveness, rationality, and safety of laparotomy management compared with uterine artery embolization (UAE) combined with methotrexate (MTX) for the treatment of deep implantation cesarean scar pregnancy (CSP II). Materials and methods: Data from 29 patients seen between June 2008 and...
School of Electronic, Information and Electrical Engineering The School of Electronic Information and Electrical Engineering (SEIEE) at Shanghai Jiao Tong University (SJTU) was established in 2001, with its glorious history traced back to 1908 when the discipline of Electric Machines was founded. With a century-long history of reputation in research and education, SEIEE is crowned as “the Cradle of Chinese Electrical Engineers”. The school now has 12 departments and principal units including the Department of Electrical Engineering, the Department of Automation, the Department of Computer Science and Engineering, the Department of Electronic Engineering, the Department of Instrument Science and Engineering, the Department of Micro-Nano Electronics, the School of Cyber Security, the School of Software, the Academy of Information Technology and Electrical Engineering, the Center for Advanced Electronic Materials and Devices, the Center for Teaching and Learning Development, and the Cooperative Medianet Innovation Center.

Objective To study the expression of intermediate? conductance? Ca2+-activatedK+ (KCa3.1) channelsin Endometrial cancer tissues and their role in regulating cell cycle of endometrial cancer cells.Methods Real?time PCR and Western blotting analysis were used to examine the expression of KCa3.1 channels in 25 normal endometrial specimens,26 atypical...
To establish a sprouting embryoid body model mimicking early embryonic vasculogenesis in human embryo. Human embryonic stem were (hESCs) were cultured on the mouse embryo fibroblasts and then were induced to differentiate to form three-dimensional EB. The hEBs were cultured in media containing various angiogenesis-related factors: vascular endothel...
The Ministry of Commerce assumed administration of the college in 1904, and in 1905 changed the college's name to Imperial Polytechnic College of the Commerce Ministry. In 1906, the college was placed under the Ministry of Posts and Telegraphs, and its name was changed to Shanghai Industrial College of the Ministry of Posts and Telegraphs. When the Republic of China was founded, the college was placed under the Ministry of Communications and its name was once again changed, this time to Government Institute of Technology of the Communications Ministry.
Large amount of clinical evidence has demonstrated that insulin resistance is closely related to oncogenesis of endometrial cancer (EC). Despite recent studies showed the up-regulatory role of insulin in G protein-coupled estrogen receptor (GPER/GPR30) expression, GPER expression was not decreased compared to control when insulin receptor was block...
Ovarian carcinoma is leading cause of death in gynecologic malignancies. The survival rate cannot be improved after routine surgery, chemotherapy, and radiotherapy. Therefore biotherapy becomes the fourth treatment pattern for ovarian carcinoma. Adequate experimental models for the development of biologic therapeutic strategies are needed. Our purp...

To examine the expressions of glyoxalase I (GLO-I) in endometrial cancer tissues and cell lines and to investigate the roles of GLO-I on proliferation and apoptosis in endometrial cancer cells. Immunohistochemistry, western blot and RT-PCR were used to investigate the expressions of GLO-I protein and mRNA in endometrial cancer tissues and Ishikawa...
... [9,25] Overall, the main reasons reported contributing to the psychosocial burden among women (anxious, fearful, self-blame, powerlessness, disbelief, depression, and anger) in this domain were lack of understanding of abnormal Pap smear results and higher perceived risk of developing cervical cancer which also have negative impact on perception of self. [10,11,26] Domain 3: Worry about human papillomavirus infectivity Women of reproductive age were found to have a significantly higher mean score not only in general but also in both individual items of this domain " worry about HPV infectivity " compared to a menopausal group of women. Our results were quite similar to the study conducted in the United States which reported that women with abnormal Pap smear results were distressed due to a sense of shame or guilt when they came to know that these cervical changes are associated with HPV and which is a sexually transmitted infection. ...
Jiao Yulu was born in Yuanquan Town of Boshan District, in Zibo city, in Shandong province, to a poor family, on August 16, 1922, during the Republic of China.[3] Both his father Jiao Fangtian (焦方田) and mother were farmers.[3] He had only four years of schooling.[3] His father hanged himself during the Second Sino-Japanese War.[3] Jiao Yulu was conscripted into the Japanese labor and he was sent to coal-mining in Fushun, Liaoning, Manchoukuo.[3] He escaped to Suqian, Jiangsu in the fall of 1943.[3] He had been a farm labourer for two years for the landowner Hu Tairong (胡泰荣).[3]
Huang Yaoshi is a fictional character in the wuxia novel The Legend of the Condor Heroes and its sequel, The Return of the Condor Heroes, by Jin Yong. He is one of the Five Greats of the wulin (martial artists' community) during the Song dynasty, alongside Wang Chongyang, Hong Qigong, Ouyang Feng and Duan Zhixing. He is nicknamed "Eastern Heretic" (東邪) for being an unorthodox radical who behaves as he wishes without showing any regard for formalities or moral ethics.[SheDiao Ch.10] He loathes the dogma of traditional rites in Chinese society and admires only genuine honour and pure love.[SheDiao Ch.10] As such, he is often regarded by his contemporaries as a cultural heretic.[SheDiao Ch.10] His nickname may be translated to "Eastern Evil" because the character Xie (邪) in his nickname also refers to "evil" and "unorthodoxy" in jianghu terminology.
School of Marxism The School of Marxism, established in 2009, including 6 Teaching and Research Department and 2 researching centers. Offers the two and half year MP with about 20 students; the PhD program with 30 students in residence. Main researching directions are Theory of Marxism, Study of Marxism in China, Education in Ideology and Politics, Foreign Marxism. The school responsible for the teaching and management of the ideological and Political Theory Course.
Objective: To detect mRNA levels and expression of CD44, CD54, CD29 and E-cadherin (E-cad) and to discuss their relationship with formation and drug resistance of ovarian cancer SKOV3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. mRNA levels and expression of CD44, CD54, CD29 and E-cad...
Ovarian cancers are heterogeneous and contain stem-like cells that are able to self-renew and are responsible for sustained tumor growth. Metastasis in peritoneal cavity occurs more frequently in ovarian cancer than in other malignancies, but the underlying mechanism remains largely unknown. We have identified that ovarian cancer stem-like cells (C...
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif...
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