Our previous studies have showed that Gankyrin expression is correlated with a malignant phenotype in endometrial carcinoma. Here, we investigated the possible role of Gankyrin in cervical disease. The increasing protein level of Gankyrin was observed in high-grade cervical intraepithelial neoplasia and carcinoma compared with benign cervical tissu...
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
Jiao Yulu was born in Yuanquan Town of Boshan District, in Zibo city, in Shandong province, to a poor family, on August 16, 1922, during the Republic of China.[3] Both his father Jiao Fangtian (焦方田) and mother were farmers.[3] He had only four years of schooling.[3] His father hanged himself during the Second Sino-Japanese War.[3] Jiao Yulu was conscripted into the Japanese labor and he was sent to coal-mining in Fushun, Liaoning, Manchoukuo.[3] He escaped to Suqian, Jiangsu in the fall of 1943.[3] He had been a farm labourer for two years for the landowner Hu Tairong (胡泰荣).[3]
The Ministry of Commerce assumed administration of the college in 1904, and in 1905 changed the college's name to Imperial Polytechnic College of the Commerce Ministry. In 1906, the college was placed under the Ministry of Posts and Telegraphs, and its name was changed to Shanghai Industrial College of the Ministry of Posts and Telegraphs. When the Republic of China was founded, the college was placed under the Ministry of Communications and its name was once again changed, this time to Government Institute of Technology of the Communications Ministry.
... ovarian diameter must be ≥ 31 mm. The presence of PFOs was evaluated binary, thereby the visualization of at least one side (unilateral)/individual was considered positive [129] . It has to be recognized that an PFO/ " PCO " is according to Netter (1990) [21] just a " clinical finding similar to splenomegaly or hepatomegaly ; cystic ovaries are found in a multiplicity of states, which have nothing in common etiologically; the clinical management varies and is dependent on the etiology " . ...
Huiyuan (Chinese: 慧遠; Wade–Giles: Hui-yüan; 334–416 AD) was a Chinese Buddhist teacher who founded Donglin Temple on Mount Lushan in Jiangxi province and wrote the text On Why Monks Do Not Bow Down Before Kings in 404 AD. He was born in Shanxi province but after a long life of Buddhist teaching he wound up in Jiangxi province, where he died in 416. Although he was born in the north, he moved south to live within the bounds of the Eastern Jin Dynasty.
RAB25 belongs to the Rab family of small GTPases and is implicated in the development of various types of human cancer. To evaluate the role of RAB25 in ovarian cancer, RAB25 was knocked down by siRNA in HEY and ES‑2 human ovarian cancer cells. Autophagy, cell growth and cell apoptosis were evaluated. The results showed that knockdown of RAB25 incr...

Huang Yaoshi is married to Feng Heng and has six apprentices. He has scores of servants on his island, who are deaf and mute. Rumours in the jianghu say that he intentionally disabled them, but in fact, they were already mute and deaf before they became his servants. He recruited them as his servants to relieve them from the social stigma of their impairments so that they can enjoy a better life on his island. However, he does not wish to promote an image of himself as a kind and compassionate person so he spread those negative rumours about himself. Only his family and apprentices know the truth.
AAeronautics and AstronauticsAgriculture and BiologyAntai College of Economic and ManagementBBiomedical EngineeringCChemistry and Chemical EngineeringChina Europe International Business SchoolChina-UK Low Carbon CollegeEElectronic, Information and Electrical EngineeringEnvironmental Sciences and EngineeringFForeign LanguagesHHumanitiesIInternational and Public AffairsKKoGuan Law SchoolLLife Sciences and BiotechnologyMMarxismMaterials Science and EngineeringMathematical SciencesMechanical Engineering Media and DesignMedicineNNaval Architecture, Ocean and Civil EngineeringPPharmacyPhysical EducationPhysics and AstronomySShanghai Advanced Institute of FinanceSJTU-ParisTech Elite Institute of Technology U UM-SJTU Joint Institute USC-SJTU Institute of Cultural and Creative Industry Z Zhiyuan College
To study the expression of the human novel gene NM23-H1B in ovarian cancer. Forty-eight samples from patients with ovarian tumor at different clinical stages and 8 from normal ovaries were examined for NM23-H1B mRNA expression by using RT-PCR, northern blot and in situ hybridization. All samples expressed NM23-H1B mRNA through RT-PCR, while the lev...
Objective: This research was carried out to investigate the effectiveness, rationality, and safety of laparotomy management compared with uterine artery embolization (UAE) combined with methotrexate (MTX) for the treatment of deep implantation cesarean scar pregnancy (CSP II). Materials and methods: Data from 29 patients seen between June 2008 and...
Huang Yaoshi is a fictional character in the wuxia novel The Legend of the Condor Heroes and its sequel, The Return of the Condor Heroes, by Jin Yong. He is one of the Five Greats of the wulin (martial artists' community) during the Song dynasty, alongside Wang Chongyang, Hong Qigong, Ouyang Feng and Duan Zhixing. He is nicknamed "Eastern Heretic" (東邪) for being an unorthodox radical who behaves as he wishes without showing any regard for formalities or moral ethics.[SheDiao Ch.10] He loathes the dogma of traditional rites in Chinese society and admires only genuine honour and pure love.[SheDiao Ch.10] As such, he is often regarded by his contemporaries as a cultural heretic.[SheDiao Ch.10] His nickname may be translated to "Eastern Evil" because the character Xie (邪) in his nickname also refers to "evil" and "unorthodoxy" in jianghu terminology.
Aim: To assess the clinical significance of hTERC amplification for cervical cancer screening detected by fluorescence in situ hybridization (FISH) and compare it with that of current screening methods within the same group. Methods: A total of one hundred and nine women were recruited in this study. All of them had liquid-based thin-prep cytologic...
... ovarian diameter must be ≥ 31 mm. The presence of PFOs was evaluated binary, thereby the visualization of at least one side (unilateral)/individual was considered positive [129] . It has to be recognized that an PFO/ " PCO " is according to Netter (1990) [21] just a " clinical finding similar to splenomegaly or hepatomegaly ; cystic ovaries are found in a multiplicity of states, which have nothing in common etiologically; the clinical management varies and is dependent on the etiology " . ...
To compare the efficacy of combination regiments of taxol given weekly plus carboplatin and taxol given every three weeks plus carboplatin. To observe the toxicity of the two regiments. To observe the two-year survival rate in the two groups. Total 125 eligible patients in 13 centers of CGOG were entered into the two arms of this randomized clinica...
... LiCl treatment can induce apoptosis in cancer cells (Kaufmann, 2011) and reduce the incidence of cancer of non-epithelial origin (Cohen et al., 1998). In addition, it has been shown that LiCl treatment can inhibit cancer cell proliferation through Wnt signaling ( Qi et al., 2006). In the present study, our results showed that LiCl treatment affects the expression of miR-17-92 cluster, which is known as oncomir-1 and plays vital roles in a variety of cellular processes such as cell proliferation and apoptosis. ...
School of Biomedical Engineering The School of Biomedical Engineering (BME) aims to satisfy the major needs of global development and meet the demand for interdisciplinary programs between medicine, science, and engineering. Based on the current frontiers of international research, major national needs, interdisciplinary programs, and the existing foundation of SJTU, BME consists the following six disciplines: Biomedical Instrumentation, Neuroscience and Engineering, Medical Imaging & Informatics, Nano-biomaterials, Systems Biology & Medicine, and Biological Sciences & Diseases. BME has been dedicated in cultivating high-level research, development, and management talents that are internationally competitive in the field of biomedical engineering.
... [9,25] Overall, the main reasons reported contributing to the psychosocial burden among women (anxious, fearful, self-blame, powerlessness, disbelief, depression, and anger) in this domain were lack of understanding of abnormal Pap smear results and higher perceived risk of developing cervical cancer which also have negative impact on perception of self. [10,11,26] Domain 3: Worry about human papillomavirus infectivity Women of reproductive age were found to have a significantly higher mean score not only in general but also in both individual items of this domain " worry about HPV infectivity " compared to a menopausal group of women. Our results were quite similar to the study conducted in the United States which reported that women with abnormal Pap smear results were distressed due to a sense of shame or guilt when they came to know that these cervical changes are associated with HPV and which is a sexually transmitted infection. ...
... However, no clear morphologic changes were found between control cells and Snail-knockdown cells. 16 Although the Ecadherin expression could not be detected in these cells at protein lever (Fig. 1a), but there is significant upregulation of E-cadherin mRNA after knockdown expression of Snail (Fig. 1b), indicating that Snail is required to suppress the expression of E-cadherin in ovarian cancer. In addition, expression of fibronectin, one of the mesenchymal markers, was greatly downregulated in the stable antisense-Snail-transfected cells when compared with the parental cells (Fig. 1b). ...
Jiaozuo (Chinese: 焦作; pinyin: Jiāozuò [tɕjáu.tswô]; postal: Tsiaotso) is a prefecture-level city in northern Henan province, China. Sitting on the northern bank of the Yellow River, it borders the provincial capital of Zhengzhou to the south, Xinxiang to the east, Jiyuan to the west, Luoyang to the southwest, and the province of Shanxi to the north.Jiaozuo is one of the core cities of the Central Plains urban agglomeration and a regional central city in the Jin-Yu border area.link
School of Mechanical Engineering The history of the School of Mechanical Engineering (ME) , Shanghai Jiao Tong University (SJTU) dates back to 1913. The School has the vision of a world-class engineering school committed to high-level education and cutting edge research. It aims to offer the best learning experience to its students, the most rewarding working environment for its faculty and staff as well as the most effective service to industry and society. Among the 334 faculty members, 124 are professors, 152 are associate professors and 58 are assistant professors, and more than 5000 students are learning here. As one of the top Schools of Mechanical Engineering in China, it strives to increase its international competitiveness and global presence through quality teaching, advanced research and close collaboration with leading universities in the world. The alumni from the School, as scientists, engineers, educators, statesmen and entrepreneurs, always make outstanding contributions to the innovation of science and technology, and the development of the society.
To investigate the inhibitory effects of Snail--a zinc finger transcription factor, anti-sense plasmid on the invasion of ovary carcinoma cell lines in vitro. Four human ovarian carcinoma cell lines ES-2, OVCAR3, HO8910, HO8910PM were analyzed for the expression of Snail and E-cadherin mRNA by RT-PCR. Then anti-Snail plasmid transfection was introd...
Obesity is generally acknowledged as a risk factor for endometrial cancer, as accumulated adipocytes partly contribute to the increased production of estrogen which is involved in dysregulated cell growth and metastasis in early endometrial carcinogenesis. Thus we evaluated in this study expression of the fat mass and obesity-associated (FTO) gene...
... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...
×