Shanghai Advanced Institute of Finance The Shanghai Advanced Institute of Finance (SAIF) was established by the Shanghai Municipal Government at Shanghai Jiao Tong University in April 2009. Its mission is to become a world class institute of research and higher learning with world class faculty. SAIF is committed to developing top talents for the financial world and to generate cutting-edge knowledge in financial theories and applications. As a member of Shanghai's financial community, it strives to contribute to the development of Shanghai as a global financial center.
OCT4 plays a critical role in the maintenance of stem cell pluripotency and proliferation, and is overexpressed in multiple human tumors, including endometrial cancer. OCT4 expression can be modulated by miR-145 and the OCT4 pseudogene 5 (OCT4-pg5), which share similar binding sites in the OCT4 3'-untranslated region. The goal of the present study...
To study the expression of intermediate-conductance-Ca(2+)-activated K(+) (IKCa1) channels in endometrial cancer and its role in regulating proliferation of endometrial cancer cells. Western blot and RT-PCR were used to examine the expression of IKCa1 channels in 13 normal endometrial specimens and 25 endometrial cancer specimens; and RNA interfere...
To evaluate the therapeutic efficacies of preserving fertility treatment in patients with early cervical cancer. Sixteen patients with early cervical cancer treated by laparoscopic vaginal radical trachelectomy and pre- or postoperative chemotherapy were analyzed retrospectively, focusing on the treatment indication and management of high risk pati...
Ovarian epithelial cancer is the leading cause of death among gynecological malignancies. FSH may increase the risk of ovarian malignancy and play an important role in ovarian carcinogenesis. Our previous studies showed that FSH increases the expression of VEGF through survivin. In this study, the function and mechanism of FSH in ovarian cancer wer...
Our previous study revealed that estrogen regulates nm23-H1 expression thus promoting cell migration-invasion via activating PIK3/Akt pathway. In this study, we explored the effect of hormone on hypoxia-inducible factor-1 (HIF-1alpha), a key factor in cancer invasion and metastasis, via activation of Akt signaling transduction pathway. We treated t...
Song of the Sea and Waves (碧海潮生曲) is a xiao piece whose tune has hypnotic effects on people. The melody can put a person into a trance and the person feels like he is floating in the ocean. Huang channels some of his inner energy into the tune when playing the piece and this increases its power. Huang Yaoshi plays this piece several times to hypnotise Zhou Botong and make him reproduce a copy of the Nine Yin Manual. He also plays it during the second test for Guo Jing and Ouyang Ke.

To identify new genetic risk factors for cervical cancer, we conducted a genome-wide association study in the Han Chinese population. The initial discovery set included 1,364 individuals with cervical cancer (cases) and 3,028 female controls, and we selected a 'stringently matched samples' subset (829 cases and 990 controls) from the discovery set...

Ovarian cancers are heterogeneous and contain stem-like cells that are able to self-renew and are responsible for sustained tumor growth. Metastasis in peritoneal cavity occurs more frequently in ovarian cancer than in other malignancies, but the underlying mechanism remains largely unknown. We have identified that ovarian cancer stem-like cells (C...


School of Materials Science and Engineering School of Materials Science and Engineering, Shanghai Jiao Tong University originated from the metal heat treatment major in 1952, and was established by merging Materials Science Department and Materials Engineering Department in 1997. The School has been ranked among ESI world top 1‰ disciplines for consecutive years, the discipline ranked 31st in 2016 QS world ranking and the 2nd among domestic disciplines. There are about 300 faculty and staff members, including 1 academicians of the Chinese Academy of Sciences,4 academicians of the Chinese Academy of Engineering, 4 YangtzeRiver Scholars and 4 winners of the National Fund for Distinguished Young Scholars of China. The School has about 1,500 students, including about 560 undergraduates, 470 master degree candidates, 360 doctoral candidates and 150 engineering masters. The School has formed 13 distinctive teaching and research teams by compacting discipline orientation and integrating academic teams.

Jiaozuo (Chinese: 焦作; pinyin: Jiāozuò [tɕjáu.tswô]; postal: Tsiaotso) is a prefecture-level city in northern Henan province, China. Sitting on the northern bank of the Yellow River, it borders the provincial capital of Zhengzhou to the south, Xinxiang to the east, Jiyuan to the west, Luoyang to the southwest, and the province of Shanxi to the north.Jiaozuo is one of the core cities of the Central Plains urban agglomeration and a regional central city in the Jin-Yu border area.link

In the year 404, Huiyuan wrote a treatise On Why Monks Do Not Bow Down Before Kings (沙門不敬王者論).[4] This book symbolized his efforts to assert the political independence of Buddhist clergy from the courts of monarchic rulers. At the same time, it was a religious and political text that aimed to convince monarchs and Confucian-minded ministers of state that followers of Buddhism were ultimately not subversive. He argued that Buddhists could make good subjects in a kingdom due to their beliefs in retribution of karma and the desire to be reborn in paradise. Despite the Buddhists' reputation of leaving their family behind for a monastic life, Huiyuan stated "those who rejoice in the Way of the Buddha invariably first serve their parents and obey their lords."[1]
... Previous studies have discovered high IKCal expressions in endometrial carcinoma, breast cancer, urinary bladder carcinoma, colon cancer, and glioblastoma cells. [4][5][6][7] This study demonstrated the close relationship between the Ca 2+ -activated K + channel and cervical cancer. [8,9] This study utilized the K + -channel blocker clotrimazole (CLT) and small hairpin ribonucleic acid (RNA) to explore the role played by (and the effect of) IKCal in the proliferation of HeLa cells. ...
Background: Insulin resistance (IR) has been well studied in the initiation and development of endometrial endometrioid carcinoma (EEC). As yet, it has been largely neglected for estrogen sensitivity in local endometrium in hyperinsulinemia-induced systemic microenvironment. The aim of this study was to investigate the role of insulin in regulating...

Up to 30% of failure rate in endometrial hyperplasia patients treated by progestin urges more detailed understanding of the mechanisms involved in progestin resistance. Survivin is a key regulator in the antiapoptotic network, and overexpression of survivin has been reported in endometrial hyperplasia and cancer. This study investigated the role of...

In the year 404, Huiyuan wrote a treatise On Why Monks Do Not Bow Down Before Kings (沙門不敬王者論).[4] This book symbolized his efforts to assert the political independence of Buddhist clergy from the courts of monarchic rulers. At the same time, it was a religious and political text that aimed to convince monarchs and Confucian-minded ministers of state that followers of Buddhism were ultimately not subversive. He argued that Buddhists could make good subjects in a kingdom due to their beliefs in retribution of karma and the desire to be reborn in paradise. Despite the Buddhists' reputation of leaving their family behind for a monastic life, Huiyuan stated "those who rejoice in the Way of the Buddha invariably first serve their parents and obey their lords."[1]

Estrogen and progestin are involved in ovarian carcinogenesis. Change in nm23-H1 expression and the PIK3/AKT pathway are involved in carcinogenesis, development, invasion and metastasis of ovarian cancers. Therefore, it is critical to understand the signaling pathways that regulate hormone-induced cell migration and invasion in ovarian cancer. We i...

To investigate the correlation of hypoxia-inducible factor (HIF)-1alpha and vascular endothelial growth factor (VEGF) or micro-vessel density (MVD). The ovarian cancer cell line SKOV3 was transplanted into nude mice to form xenogeneic tumor. Mice were treated with rapamycin 4 mg/kg, sulindac 100 mg/(kg.d) and saline 200 microl respectively. Express...
China Europe International Business School China Europe International Business School (CEIBS), a joint-venture for management education, was co-founded by the Chinese government and European Union (EU) in 1994, with Shanghai Jiao Tong University and the EFMD serving as its executive partners. As China's only business school to originate from government-level collaboration, CEIBS is committed to educating responsible leaders versed in "China Depth, Global Breadth" in line with its motto of "Conscientiousness, Innovation and Excellence". Leaders from the Chinese central government and the EU have respectively lauded CEIBS as "a cradle of excellent executives" and "a role model of EU-China cooperation". CEIBS offers MBA, EMBA, Global EMBA, Finance MBA and Executive Education programmes. Renowned for its academic rigour, CEIBS is the first business school on the Chinese mainland to have been accredited by both EQUIS and AACSB and the only business school in Asia to have simultaneously made it to the Financial Times' top 30 list of MBA, EMBA and Executive Education programmes.

Our previous study showed that Octamer-binding transcription factor 4 (OCT4) expression was upregulated and significantly associated with histological grade through the analysis of OCT4 expression in 159 ovarian cancer tissue samples, and OCT4 mediated follicle-stimulating hormone (FSH)-induced anti-apoptosis in epithelial ovarian cancer. Neverthel...

... ovarian diameter must be ≥ 31 mm. The presence of PFOs was evaluated binary, thereby the visualization of at least one side (unilateral)/individual was considered positive [129] . It has to be recognized that an PFO/ " PCO " is according to Netter (1990) [21] just a " clinical finding similar to splenomegaly or hepatomegaly ; cystic ovaries are found in a multiplicity of states, which have nothing in common etiologically; the clinical management varies and is dependent on the etiology " . ...


Snail, a key inducer of epithelial-mesenchymal transition (EMT), plays an important role in cancer metastasis. To better understand the role of Snail in the metastasis of ovarian carcinoma, expression of Snail was knocked down by antisense-Snail in the highly metastatic ovarian cancer cell line HO8910PM. Gene array analysis revealed that blocking S...
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif...
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