Objective: To investigate the chemosensitivity of ovarian cancer SK-OV-3ip1 multicellular aggregates (MCA) to cisplatin and taxol and to explore the possible mechanisms. Methods: Liquid overlay system was employed to obtain MCA. We detected the resistance using trypan blue exclusion testing, clonogenic assay, cell cycle profiles and apoptosis with...

Purpose: It has previously been shown that follicle-stimulating hormone (FSH) and its receptor contribute to epithelial ovarian cancer (EOC) development. Epithelial-mesenchymal transition (EMT) is the early event of metastasis in cancer. Therefore, the aim of this study was to investigate the roles of FSH and the FSH receptor (FSHR) in EMT of EOC....
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
Henan Polytechnic University (HPU)[1], with a history of nearly 100 years, is the first mining university in Chinese history. Its former is Jiaozuo Coal Mining School which was established by the British Syndicate Co. Ltd., in 1909. It has changed its names several times in the course of development, namely, FuZhong Coal Mining University, Jiaozuo Private Institute of Technology, North-west Institute of Technology, Jiaozuo National Institute of Technology, Jiaozuo Mining Institute and Jiaozuo Institute of Technology. The University resumed its name of Henan Polytechnic University in 2004.
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif...
OCT4, a stem cell marker, is overexpressed in several types of human cancer and can induce resistance to chemotherapy and inhibition of apoptosis. We previously demonstrated that human follicle stimulating hormone (FSH) can inhibit ovarian cancer cell apoptosis. However, the role of OCT4 in FSH-induced inhibition of apoptosis has not been reported...
School of Electronic, Information and Electrical Engineering The School of Electronic Information and Electrical Engineering (SEIEE) at Shanghai Jiao Tong University (SJTU) was established in 2001, with its glorious history traced back to 1908 when the discipline of Electric Machines was founded. With a century-long history of reputation in research and education, SEIEE is crowned as “the Cradle of Chinese Electrical Engineers”. The school now has 12 departments and principal units including the Department of Electrical Engineering, the Department of Automation, the Department of Computer Science and Engineering, the Department of Electronic Engineering, the Department of Instrument Science and Engineering, the Department of Micro-Nano Electronics, the School of Cyber Security, the School of Software, the Academy of Information Technology and Electrical Engineering, the Center for Advanced Electronic Materials and Devices, the Center for Teaching and Learning Development, and the Cooperative Medianet Innovation Center.
Objectives: The objective of this study was to analyze the relationship among the protein levels of MCM7, p63, and human papillomavirus (HPV) in different cervical lesion tissues and appraise their predictive value in evaluating severity of cervical disease. Methods: Twelve normal cervix or chronic cervicitis, 42 squamous intraepithelial lesions...
Zhou Botong realised that he had been tricked by Huang Yaoshi so he returned to Peach Blossom Island to demand an explanation from Huang. Huang Yaoshi was still embattled by the loss of his wife. Zhou Botong's confrontational attitude merely fuelled the anger and frustration in him. When Huang Yaoshi blamed Zhou Botong for his wife's death, Zhou retorted angrily that he had also suffered in a similar experience with Liu Ying. Huang Yaoshi and Zhou Botong started fighting but neither of them was able to defeat his opponent. Huang Yaoshi imprisoned Zhou Botong on his island by sealing all possible exit routes. Zhou Botong roamed the island and settled in a cave for the next 15 years. During that period of time, Huang Yaoshi and Zhou Botong taunted each other to fight and kept themselves occupied with their conflict. Their feud is resolved when Guo Jing visits the island and meets Zhou Botong.

Epithelial ovarian cancer (EOC) remains the most lethel gynecological malignancy. In the absence of an effective screening strategy, two thirds of patients are diagnosed in advanced clinical stage. Despite chemotherapy with cisplatin and paclitxel, primary or acquired chemoresistance faciltates survival of cancer cells, resulting in disease recurre...


School of Aeronautics and Astronautics The School of Aeronautics and Astronautics (SAA) is the main body of SJTU to cultivate talents for aerospace. The school consist of 3 departments and 2 research centers, namely, Department of Aircraft Design, Department of Aerospace Information and Control, Department of Propulsion, Near Space Research Center and J.C. Wu Center of Aerodynamics. Currently, SAA has more than 60 faculty members, 15 professors/researchers, 28 associate professors/associate researchers, which includes 2 Academician of the Chinese Academy of Engineering, 3 National “1000 Plan” Scholars, 2 Cheung Kong Professor. The school has 72 Doctoral Candidates, 205 Master Candidates, 112 Undergraduate students and 38 international students. SAA has maintained close and wide-ranging research cooperation and academic exchanges with many famous overseas universities and research institutions. The school also engages in visionary research projects to meet future demands and train highly qualified aerospace professionals for the future development of the world’s aerospace industry.
AAeronautics and AstronauticsAgriculture and BiologyAntai College of Economic and ManagementBBiomedical EngineeringCChemistry and Chemical EngineeringChina Europe International Business SchoolChina-UK Low Carbon CollegeEElectronic, Information and Electrical EngineeringEnvironmental Sciences and EngineeringFForeign LanguagesHHumanitiesIInternational and Public AffairsKKoGuan Law SchoolLLife Sciences and BiotechnologyMMarxismMaterials Science and EngineeringMathematical SciencesMechanical Engineering Media and DesignMedicineNNaval Architecture, Ocean and Civil EngineeringPPharmacyPhysical EducationPhysics and AstronomySShanghai Advanced Institute of FinanceSJTU-ParisTech Elite Institute of Technology U UM-SJTU Joint Institute USC-SJTU Institute of Cultural and Creative Industry Z Zhiyuan College
Ovarian epithelial cancer is the leading cause of death among gynecological malignancies. FSH may increase the risk of ovarian malignancy and play an important role in ovarian carcinogenesis. Our previous studies showed that FSH increases the expression of VEGF through survivin. In this study, the function and mechanism of FSH in ovarian cancer wer...
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
When the Japanese surrendered in 1945, neither the Communist Party of China (CPC) nor the Kuomintang KMT trusted each other or were actively cooperating. After American-sponsored attempts to negotiate a coalition government failed in 1946, the Chinese Civil War resumed. The CPC defeated the Nationalists in 1949, forcing Chiang's government to retreat to Taiwan. During the evacuation, a part of faculty and alumni was taken to Taiwan by Chiang Kai-shek, founding National Chiao Tung University in Taiwan in 1958.
Antai College of Economics and Management Antai College of Economics and Management (ACEM), Shanghai Jiao Tong University boasts a rich history and tradition which dates back to the Business School of Nan Yang Public School founded in 1903. ACEM is dedicated to educate economic and management talents with international competencies. It promotes scientific and academic innovation, caters to economic and social development, and supports the growth of business. After over 30 years’ unremitting efforts, ACEM has established itself as a modern business school with a good reputation home and abroad, and the first business school in mainland China to have been triply accredited by AACSB, EQUIS and AMBA, the three largest and most influential business school accreditation associations in the world.

The college achieved world renown in the 1930s, and was referred to as the "Eastern MIT".[9] In 1938, the Ministry of Education assumed administration of the university and renamed it to National Chiao Tung University (Chinese: 國立交通大學), the name by which daughter institution National Chiao Tung University in Taiwan, is known to this day. In 1943, the graduate school was founded.

On February 13, 2004, Yuntai Mountain as the fifth in the world, the third in the country China, was named the world's first World Geopark by UNESCO and caused attention at home and abroad. Meanwhile, Yuntaishan is also a national scenic spot, National Civilized Scenic Area, the first national AAAAA-level scenic spot, national natural heritage, national forest parks, national macaque nature reserve. Yuntain Mountain also has Asia's highest head drop waterfall.
Our previous study revealed that estrogen regulates nm23-H1 expression thus promoting cell migration-invasion via activating PIK3/Akt pathway. In this study, we explored the effect of hormone on hypoxia-inducible factor-1 (HIF-1alpha), a key factor in cancer invasion and metastasis, via activation of Akt signaling transduction pathway. We treated t...

To investigate the inhibitory effects of Snail--a zinc finger transcription factor, anti-sense plasmid on the invasion of ovary carcinoma cell lines in vitro. Four human ovarian carcinoma cell lines ES-2, OVCAR3, HO8910, HO8910PM were analyzed for the expression of Snail and E-cadherin mRNA by RT-PCR. Then anti-Snail plasmid transfection was introd...
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