The purpose of the study was to explore the role and mechanism of ataxia-telangiectasia mutated (ATM) protein in endometrial carcinogenesis. A reverse-phase protein array (RPPA) was used to analyze the expression of ATM signal pathway proteins in Ishikawa and progesterone-insensitive Ishikawa. ATM expression was detected in endometrium specimens by...
Since 2003, Shanghai Jiao Tong University has produced the Academic Ranking of World Universities[24] which analyzes the top universities in the world on quality of faculty (40%), research output (40%), quality of education (10%) and performance vs. size (10%).[25] Its ranking is exclusively of research universities, mainly in the empirical sciences.
... Likewise, our network analyses further support the role of these two GalNAc-Ts in modulating EOC tumorigenesis. Indeed major gene nodes with proven implications in EOC tumorigenesis, including VEGF, PI3K, EZH2, IQGAP1, and HOXD10 [34][35][36][37][38], were downregulated upon GALNT3 ablation. Moreover, multiple gene nodes reported to be involved in EOC progression (such as CUL1 EEF2, PTN, UCHL1, CBX5, USP14, and BMI-1 [39][40][41][42][43][44]) were strongly affected by the GALNT3/T6 double KO. ...
Our previous study showed that Octamer-binding transcription factor 4 (OCT4) expression was upregulated and significantly associated with histological grade through the analysis of OCT4 expression in 159 ovarian cancer tissue samples, and OCT4 mediated follicle-stimulating hormone (FSH)-induced anti-apoptosis in epithelial ovarian cancer. Neverthel...
School of Chemistry and Chemical Engineering School of Chemistry and Chemical Engineering (SCCE) has a glorious history dating back to 1928. Inspired by the mottos “Prudence, Pragmaticality, Erudition, Innovation” at SCCE, we have been highly successful in the development of academic disciplines, research, and education excellence. After years of efforts, we have so far more than 160 faculty members, among whom there are four academicians of the Chinese Academy of Science, two chair professors supported by the “Thousand Talents Program”, and 11 experts supported by the “Thousand Young Talents Program”; a large number of scholars are supported by the National Science Fund for Distinguished Young Scholars, the “Cheung Kong Scholars Program”, the “National 973 Project”, the “National Science Fund for Outstanding Scholars”, etc. We provide comprehensive education programs including three undergraduate programs, four postgraduate programs(two master and two Ph.D. programs), visiting student programs and post-doctoral programs. With its energetic faculty and various education programs, SCCE has been considered as one of the long-standing educators in the field of chemistry and chemical engineering in China.
To study the expression of glucose transporter-1 (GLUT1) and its correlation with basic fibroblast growth factor (bFGF) and proliferating cell nuclear antigen (PCNA) in epithelial ovarian neoplasm. Streptavidin-peroxidase complex technique was used to examine the expression of GLUT1, bFGF and PCNA protein in six cases of normal ovarian tissue, 20 c...
In Chinese grammar de hua (的话) is a very common and important word. It is used either alone or in combination with other words to express “if”. De hua is probably the most common way to express “if” in Chinese, in fact. Because of this, all students of Mandarin Chinese should be familiar with how to use this word, and that's what this guide is for.

To investigate the effect of glycogen synthase kinase-3beta (GSK-3beta) on the proliferation of human ovarian cancer cells. Two human ovarian cancer cell lines SKOV3 and ES-2 were analysed for the expression of GSK-3beta and phosphorylated GSK-3beta (pGSK-3beta) by Western blot analysis. Cell growth curve analysis done by cell count was used to inv...


Objective: To investigate the expression of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) and the relationship with cell cycle profiles in ovarian cancer SK-OV-3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. Expression of P-gp and MRP was detected with flow cyt...

Estrogen and progestin are involved in ovarian carcinogenesis. Change in nm23-H1 expression and the PIK3/AKT pathway are involved in carcinogenesis, development, invasion and metastasis of ovarian cancers. Therefore, it is critical to understand the signaling pathways that regulate hormone-induced cell migration and invasion in ovarian cancer. We i...
To study the expression of VEGF, KDR, MMP-1, and its transcription factor Ets-1 on the interstitial neovasculogenesis in human cervical carcinoma on molecular level, which may provide further theoretic bases on judgement of prognosis and explain interregularity between neovasculagenetic factors. VEGF, KDR, MMP-1, and Ets-1 were detected in 87 cervi...
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