To study the expression of VEGF, KDR, MMP-1, and its transcription factor Ets-1 on the interstitial neovasculogenesis in human cervical carcinoma on molecular level, which may provide further theoretic bases on judgement of prognosis and explain interregularity between neovasculagenetic factors. VEGF, KDR, MMP-1, and Ets-1 were detected in 87 cervi...
p53 is the most commonly mutated tumor suppressor gene in human cancers. In addition to the loss of tumor suppression function and exertion of dominant-negative effects over the remaining wild-type protein, several p53 mutants can gain novel oncogenic functions (gain-of-function, GOF) that actively regulate cancer development and progression. In hu...

Obesity is generally acknowledged as a risk factor for endometrial cancer, as accumulated adipocytes partly contribute to the increased production of estrogen which is involved in dysregulated cell growth and metastasis in early endometrial carcinogenesis. Thus we evaluated in this study expression of the fat mass and obesity-associated (FTO) gene...
To investigate natural spontaneous menopausal age, menstruation span and their relationship with menarche age and parity in Pudong district of Shanghai. From Jan 2007 to Jul 2008, 15 083 spontaneous menopause women undergoing cervical cancer screening were enrolled in this study. The questionnaire included menarche age, parity, spontaneous menopaus...
Chemoresistance is the major obstacle to cure endometrial cancer, whereas metformin has demonstrated sensitization to chemotherapy in endometrial cancer. A novel finding states that isocitrate dehydrogenase 1 (IDH1) involves in cancer chemoresistance. Recent studies have revealed that epigenetic modifications facilitate chemoresistance. However, wh...
School of Medicine SJTUSM was formally approved under the“211 Project” as a state key university for full development in November, 1997. In July, 2005, Shanghai Jiao Tong University and Shanghai Second Medical University merged to form the new Shanghai Jiao Tong University, jointly supported by Shanghai Municipal Government and the Ministry of Education. In November, 2010, SJTUSM became one of the first ten universities jointly supported by the Ministry of Health and the Ministry of Education. The rich historic background of over one hundred years and heroic journey of more than 50 years have eventually brought about a research-oriented medical school with all-round development in medical education, clinical services, and scientific research, as well as other social services, a medical school with outstanding features and distinct advantages, a strong faculty, and remarkable academic achievements. In the new round of evaluating disciplines in degree and graduate programs organized by the Ministry of Education in 2009, clinical medicine of SJTUSM ranked first nationally, and the comprehensive strength of various disciplines belonged to the first echelon of the nation's medical schools.
... These clinical and basic science studies therefore suggest that P4 might be useful as an adjunct treatment for ovarian cancer. In fact one study using a xenograph ovarian tumor model has shown that high doses of P4 enhance the apoptotic action of cisplatin [5], which is consistent with a very limited clinical trial data [6]. Unfortunately other trials in both animal and humans have been relatively unsuccessful (See review by Ho [2]). ...

Most buildings on campus were influenced by American architecture, while the main gate, which was built in 1935, is of traditional Chinese style reflecting the University's earlier status as the "Imperial Polytechnic College". The approaches to the main gate were via a series of marble bridges, similar to, although smaller than, those built in front of Tiananmen. However, recent road expansions have demolished the river as well as most of bridges. A copy of this famous gate scene have been built on the east of Minhang campus.
Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events that lead to progestin resistance and to find a possible way to reverse progestin resistance in endometrial cancer, we established a progestin-resistant Ishikawa cell line by long-term progestin trea...

School of Mathematical Sciences The School of Mathematical Sciences (SMS) enjoys a rich history dating back to the establishment of Department of Mathematics in 1928, 32 years after the founding of the university. One evidence of its place in modern mathematics in China is that the first Congress of the Chinese Mathematical Society was held in 1935 at SJTU. In 2014, the Department of Mathematics was selected by the central government as one of the first four Model Schools for Internationalization, which encourages us to be more internationalization in its practices, vision and outlook. With the growth in size, it was reorganized into the School of Mathematical Sciences in December 2015. With more than 100 faculties members, the school now consists of 3 departments (Mathematics, Applied and Computational Mathematics, and Statistics) and 1 center (Research Center for Mathematics Education).

To investigate the effects of sulindac metabolites on the proliferation and apoptosis of human umbilical vein endothelial cell line ECV304 in vitro. The proliferation of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. The cell cycle, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM) and electron mi...


A long-term treatment with progestin commonly results in progestin resistance in endometrial cancer. So, the aim of this study was to investigate the role of glyoxalase I (GloI), a mediator of chemotherapy resistance, in metformin reversal of progestin resistance in endometrial carcinoma. The proliferation variety of endometrial cancer cells was de...

Students from SJTU have won top prizes in various competitions, including ACM International Collegiate Programming Contest, International Mathematical Contest in Modeling and Electronics Design Contests. Famous alumni of SJTU or its predecessors include Jiang Zemin, James S.C. Chao Lu Dingyi, Ding Guangen, Wang Daohan, Qian Xuesen, Wu Wenjun, Zou Taofen, Mao Yisheng, Cai Er, Huang Yanpei, Shao Lizi, Wang An, David K. Cheng, Jimmy H. C. Lin and many more. More than 200 of the academicians of the Chinese Academy of Sciences and Chinese Academy of Engineering are alumni of Jiao Tong University.


Ovarian clear cell adenocarcinoma (OCCA) is an aggressive ovarian malignancy with a poor prognosis. The role of estrogen receptor β (ERβ) in the development of OCCA remains to be clarified. To investigate the action of ERβ in the proliferation and invasion of OCCA cells, the ES-2 cell line was stably transfected with full-length human ERβ cDNA, and...
Its population was 3,700,000 at the 2016 census whom 1,301,732 live in the built-up area made of 4 urban districts (Jiefang, Shanyang, Zhongzhan and Macun) and Bo'ai County being urbanized. Jiaozuo enjoys a humid subtropical climate with continental climate influences. Winters are cool and relatively dry while summers are hot and often rainy. Average temperature ranges from 0.3 °C in January to 27.5 °C in July. Extremes exist from -22.4 °C to 43.6 °C. Precipitation averages 659 mm. 
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