Early detection and monitoring the treatment remain the most important factors in improving long-term survival of ovarian cancer patients. New biomarkers that individually or in combination improve the diagnostic performance of existing tumor markers are critically needed. This study uses proteomic approaches to identify new biomarkers for detectio...

To examine the expressions of glyoxalase I (GLO-I) in endometrial cancer tissues and cell lines and to investigate the roles of GLO-I on proliferation and apoptosis in endometrial cancer cells. Immunohistochemistry, western blot and RT-PCR were used to investigate the expressions of GLO-I protein and mRNA in endometrial cancer tissues and Ishikawa...

A long-term treatment with progestin commonly results in progestin resistance in endometrial cancer. So, the aim of this study was to investigate the role of glyoxalase I (GloI), a mediator of chemotherapy resistance, in metformin reversal of progestin resistance in endometrial carcinoma. The proliferation variety of endometrial cancer cells was de...
China Huiyuan Juice Group Limited (Chinese: 中国汇源果汁集团有限公司; pinyin: Zhōngguó Huìyuán Guǒzhī Jítuán Yǒuxiàn Gōngsī) (SEHK: 1886), established in 1992 and headquartered in Beijing, is the largest privately owned juice producer in China.[1] It is engaged in the manufacture and sales of juice and other beverage products. Its products include fruit juice and vegetable juice, nectars, bottled water, tea, and dairy drinks.[2]
Ovarian epithelial cancer is the leading cause of death among gynecological malignancies. FSH may increase the risk of ovarian malignancy and play an important role in ovarian carcinogenesis. Our previous studies showed that FSH increases the expression of VEGF through survivin. In this study, the function and mechanism of FSH in ovarian cancer wer...
... In order to investigate their capability to acquire a "mesenchymal-like" phenotype, we exposed these cells to both FSH and epidermal growth factor (EGF) that are well known to promote the epithelial-to-mesenchymal transition (EMT) in different cell models [37][38][39][40][41]. Thus, adherent "spindle-like" cells appeared after 48 h of culture and developed a monolayer within about 15 days (Figure 5a). ...
To examine the expressions of glyoxalase I (GLO-I) in endometrial cancer tissues and cell lines and to investigate the roles of GLO-I on proliferation and apoptosis in endometrial cancer cells. Immunohistochemistry, western blot and RT-PCR were used to investigate the expressions of GLO-I protein and mRNA in endometrial cancer tissues and Ishikawa...
Neovascularization is essential for tumor growth and metastasis. An adequate vasculature feeds tumor growth and enhances the potential of metastasis. For many years, tumor vessels were thought to be lined exclusively by endothelial cells (ECs). However, therapeutic benefits from the promising antiangiogenic strategy targeting genetically stable ECs...

Recent studies have suggested that follicle-stimulating hormone (FSH) plays an important role in ovarian epithelial carcinogenesis. We demonstrated that FSH stimulates the proliferation and invasion of ovarian cancer cells, inhibits apoptosis, and facilitates neovascularisation. Our previous work has shown that transient receptor potential channel...


Huang Yaoshi makes several brief appearances in the sequel. He rescues Cheng Ying from Li Mochou and accepts the child as his student. He develops a special bond with Yang Guo as both of them share the same distaste for the societal norms of their time, and he teaches Yang Guo two of his celebrated skills. Huang Yaoshi also participates in the defence of Xiangyang from Mongol invaders. At the end of the novel, he retains his original title as "Eastern Heretic" of the new "Five Greats" on Mount Hua, alongside Zhou Botong, Yang Guo, Guo Jing and Yideng.

In the year 404, Huiyuan wrote a treatise On Why Monks Do Not Bow Down Before Kings (沙門不敬王者論).[4] This book symbolized his efforts to assert the political independence of Buddhist clergy from the courts of monarchic rulers. At the same time, it was a religious and political text that aimed to convince monarchs and Confucian-minded ministers of state that followers of Buddhism were ultimately not subversive. He argued that Buddhists could make good subjects in a kingdom due to their beliefs in retribution of karma and the desire to be reborn in paradise. Despite the Buddhists' reputation of leaving their family behind for a monastic life, Huiyuan stated "those who rejoice in the Way of the Buddha invariably first serve their parents and obey their lords."[1]

Ovarian clear cell adenocarcinoma (OCCA) is an aggressive ovarian malignancy with a poor prognosis. The role of estrogen receptor β (ERβ) in the development of OCCA remains to be clarified. To investigate the action of ERβ in the proliferation and invasion of OCCA cells, the ES-2 cell line was stably transfected with full-length human ERβ cDNA, and...


Persistent unopposed estrogen stimulation is a central oncogenic mechanism driving the formation of type I endometrial cancer (EC). Recent epidemiologic and clinical studies of EC have also revealed a role for insulin resistance, clinically manifested by chronic inflammation. However, the role of inflammation in estrogen-driven EC is not well chara...


China Huiyuan Juice Group Limited (Chinese: 中国汇源果汁集团有限公司; pinyin: Zhōngguó Huìyuán Guǒzhī Jítuán Yǒuxiàn Gōngsī) (SEHK: 1886), established in 1992 and headquartered in Beijing, is the largest privately owned juice producer in China.[1] It is engaged in the manufacture and sales of juice and other beverage products. Its products include fruit juice and vegetable juice, nectars, bottled water, tea, and dairy drinks.[2]
Huang Yaoshi later regrets bitterly for inflicting such a heavy punishment on his innocent apprentices. He sets off to find his daughter, who has left home after quarrelling with her father. He meets Mei Chaofeng at Guiyun Manor on Lake Tai, where Lu Chengfeng has settled down. He agrees that Mei Chaofeng has been duly punished since she has lost her sense of sight and her husband. He forgives her and asks her to find his other apprentices and bring them back to the manor so he can heal their legs. However, he never saw his other apprentices again: Chen Xuanfeng was killed by Guo Jing; Qu Lingfeng was killed by Shi Yanming; Wu Mianfeng died of illness; Feng Mofeng has become a blacksmith and is killed by Jinlun Guoshi in the sequel. Huang Yaoshi later accepts Lu Chengfeng's son, Lu Guanying, and Qu Lingfeng's daughter, Shagu, as his grand-apprentices.

Students from SJTU have won top prizes in various competitions, including ACM International Collegiate Programming Contest, International Mathematical Contest in Modeling and Electronics Design Contests. Famous alumni of SJTU or its predecessors include Jiang Zemin, James S.C. Chao Lu Dingyi, Ding Guangen, Wang Daohan, Qian Xuesen, Wu Wenjun, Zou Taofen, Mao Yisheng, Cai Er, Huang Yanpei, Shao Lizi, Wang An, David K. Cheng, Jimmy H. C. Lin and many more. More than 200 of the academicians of the Chinese Academy of Sciences and Chinese Academy of Engineering are alumni of Jiao Tong University.
Human embryonic stem (hES) cells are able to give rise to a variety of cell lineages under specific culture condition. An effective strategy for stable genetic modification in hES cells may provide a powerful tool for study of human embryogenesis and cell-based therapies. However, gene silences are documented in hES cells. In current study, we inve...
To evaluate the laparoscopic operation for early ovarian malignant tumor with low risk. Ten patients with ovarian malignant tumor who underwent laparoscopic total hysterectomy, pelvic lymph nodes dissection, bilateral adnexectomy, ovarian aortic and vein high ligation, omentectomy, and additional appendectomy. Eleven patients with the same diagnosi...

To express tumor necrosis factor related apoptosis inducing ligand (TRAIL) protein using endothelial progenitor cell (EPC) and observe antitumor activity of secreted TRAIL in cell culture supernatant. EPC were isolated by immunomagnetic sorting. Human TRAIL plasmid was transfected into EPC by lipofectamine 2000. The cell culture supernatant was har...

... Likewise, our network analyses further support the role of these two GalNAc-Ts in modulating EOC tumorigenesis. Indeed major gene nodes with proven implications in EOC tumorigenesis, including VEGF, PI3K, EZH2, IQGAP1, and HOXD10 [34][35][36][37][38], were downregulated upon GALNT3 ablation. Moreover, multiple gene nodes reported to be involved in EOC progression (such as CUL1 EEF2, PTN, UCHL1, CBX5, USP14, and BMI-1 [39][40][41][42][43][44]) were strongly affected by the GALNT3/T6 double KO. ...
School of Physics and Astronomy The physics department of Shanghai Jiao Tong University was initially established in 1928, and was one of the earliest physics programs in China. Starting from 2007, the University made a strategic decision to rebuild a first-class physics program and started to invest newly on several subfields of physics, such as particle and nuclear physics, laser & plasma physics. After further incorporating astronomy and astrophysics in the year of 2016, the department was renamed the School of Physics and Astronomy. The School currently has now sixty-six full professors and forty-three distinguished research fellows which is equivalent to tenure track assistant professors in the US system. It has seven research institutes. The School sets up its mission to meet the Chinese national strategic demands in physical sciences and related interdisciplinary fields. It strives to establish a world-class research-education center of physical sciences that aim to solve scientific problems of substantial importance and to cultivate next generation of leading physicists. At present, the School covers two first-class disciplines of physics and astronomy. It has become one of the three most comprehensive physics schools in C-9 group, one of the four physics schools who boast national collaborative innovation research centers, and one of the first batch of six pilot institutes in Shanghai Jiao Tong University to build the world-class universities. It is acknowledged as one of the most competitive, fastest-growing, and comprehensive physics colleges in China.
Objective: This research was carried out to investigate the effectiveness, rationality, and safety of laparotomy management compared with uterine artery embolization (UAE) combined with methotrexate (MTX) for the treatment of deep implantation cesarean scar pregnancy (CSP II). Materials and methods: Data from 29 patients seen between June 2008 and...
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