Zhiyuan College The Zhiyuan College, established in January 2010, offers “Zhiyuan Honors Program” to the top 5% SJTU undergraduates. Today, Zhiyuan has seven undergraduate programs: Mathematics, Physics, Life Science, Computer Science, Chemistry, Engineering and Biomedical Science. Aiming at cultivating top-notch talents into international academic masters, Zhiyuan College has recruited a group of eminent scholars from around the world to build first-class faculty team. Each year, Zhiyuan admits 350 students and there are 433 alumni worldwide currently, 90% of whom are pursuing further studies at top domestic and international universities and institutions. In addition to having a strong academic record, students who show a strong interest and the potential to pursue a research career are selected. In 2014, the talent training model of Zhiyuan College won the first-class award of “National Teaching Achievement Award”; and in 2016, “Zhiyuan Model” won “Cultivating Curiosity Award” and “Natural Sciences Award” of “Reimagine Education 2016”, which is jointly hosted by Wharton School of the University of Pennsylvania and QS—international institution for world university rankings on education.
In the same year, Feng Heng was pregnant with Huang Rong. When she learnt that the copy she wrote had been stolen, she attempted to write another from memory for her husband. However, the stress was too much for her to bear so she died shortly after giving birth to Huang Rong. Huang Yaoshi was deeply tramautised by the loss of his wife and driven to near-insanity. He vented his anger on his other four apprentices (Qu Lingfeng, Lu Chengfeng, Wu Mianfeng and Feng Mofeng) by crippling them and banishing them from his island.
Genistein, the most abundant phytoestrogen in soybeans, may bind to estrogen receptors and perform anticancer activities. Choriocarcinoma is a malignant, trophoblastic and aggressive cancer of the placenta. Few studies are currently available concerning the effects of genistein on choriocarcinoma. In the present study, we investigated the effect of...
In June 1962, he was appointed Communist Party Secretary of Weishi County. In December, he became the Second Communist Party Secretary of Lankao County. This region had declined into poverty and ignorance. The county had long been plagued by dust storms, waterlogging, and alkaline lands.[3] Jiao Yulu devoted his energies to fight economic backwardness. He mobilized the local residents to contend with the poor natural conditions. Due to years of toil, Jiao Yulu broke down from constant overwork and he was diagnosed with liver cancer. But he continued his struggle against natural disasters. On May 14, 1964, he died of liver cancer, aged 42.[3]
School of Life Sciences and Biotechnology The School of Life Sciences and Biotechnology was jointly founded by Shanghai Jiao Tong University and the Chinese Academy of Sciences (Shanghai branch) in 1997. The 139 faculty members, including 51 full professors and 60 associate professors, are dedicated to cultivating diverse and unique talents in undergraduate students and postgraduate researchers. The School is also home to the State Key Laboratory of Microbial Metabolism and the Key Laboratory for Genetics Development and Neuropsychiatric Disorder. Our faculties, led by two prominent members of the Chinese Academy of Sciences, have earned numerous prestigious awards and international recognitions. By the 2017 ESI-based matrix, we ranked in the top 1% world-wide in Biology and Biochemistry, Molecular Biology and Genetics, Microbiology, and Plant and Animal Science. Hosting two state-level education bases, we administer a six-year combined bachelor-master program and an eight-year bachelor-master-PhD program. 1193 students are currently enrolled, including 303 undergraduates and 890 graduate students.

Sun Min, wife of a Chinese businessman, was found guilty of insider trading in Huiyuan shares by the Market Misconduct Tribunal in Hong Kong. The businessman, Mo Feng, and Sun purchased 8.61 million shares in the company between 30 July and 29 August 2008, at between HK$3.78 and 4.66 (US$0.48–$0.60), then resold their shares HK$10.24–$11.12 (US$1.21–$1.43) each on 3–4 Sept. 2008, after Huiyuan's stock price had surged after the proposed takeover was announced. A profit of HK$55.1 million (US$7.09 million) was made from the trade.[9] Sun was convicted of having dealt in 3.13 million Huiyuan shares in August 2008[10] and was fined HK$20 million (US$2.56 million), the largest ever imposed for the crime in the territory.[11]
p53 is the most commonly mutated tumor suppressor gene in human cancers. In addition to the loss of tumor suppression function and exertion of dominant-negative effects over the remaining wild-type protein, several p53 mutants can gain novel oncogenic functions (gain-of-function, GOF) that actively regulate cancer development and progression. In hu...
To study the expression of the human novel gene NM23-H1B in ovarian cancer. Forty-eight samples from patients with ovarian tumor at different clinical stages and 8 from normal ovaries were examined for NM23-H1B mRNA expression by using RT-PCR, northern blot and in situ hybridization. All samples expressed NM23-H1B mRNA through RT-PCR, while the lev...
To establish a sprouting embryoid body model mimicking early embryonic vasculogenesis in human embryo. Human embryonic stem were (hESCs) were cultured on the mouse embryo fibroblasts and then were induced to differentiate to form three-dimensional EB. The hEBs were cultured in media containing various angiogenesis-related factors: vascular endothel...
Neovascularization is essential for tumor growth and metastasis. An adequate vasculature feeds tumor growth and enhances the potential of metastasis. For many years, tumor vessels were thought to be lined exclusively by endothelial cells (ECs). However, therapeutic benefits from the promising antiangiogenic strategy targeting genetically stable ECs...
Huang Yaoshi makes several brief appearances in the sequel. He rescues Cheng Ying from Li Mochou and accepts the child as his student. He develops a special bond with Yang Guo as both of them share the same distaste for the societal norms of their time, and he teaches Yang Guo two of his celebrated skills. Huang Yaoshi also participates in the defence of Xiangyang from Mongol invaders. At the end of the novel, he retains his original title as "Eastern Heretic" of the new "Five Greats" on Mount Hua, alongside Zhou Botong, Yang Guo, Guo Jing and Yideng.
... Previous studies have discovered high IKCal expressions in endometrial carcinoma, breast cancer, urinary bladder carcinoma, colon cancer, and glioblastoma cells. [4][5][6][7] This study demonstrated the close relationship between the Ca 2+ -activated K + channel and cervical cancer. [8,9] This study utilized the K + -channel blocker clotrimazole (CLT) and small hairpin ribonucleic acid (RNA) to explore the role played by (and the effect of) IKCal in the proliferation of HeLa cells. ...
School of Materials Science and Engineering School of Materials Science and Engineering, Shanghai Jiao Tong University originated from the metal heat treatment major in 1952, and was established by merging Materials Science Department and Materials Engineering Department in 1997. The School has been ranked among ESI world top 1‰ disciplines for consecutive years, the discipline ranked 31st in 2016 QS world ranking and the 2nd among domestic disciplines. There are about 300 faculty and staff members, including 1 academicians of the Chinese Academy of Sciences,4 academicians of the Chinese Academy of Engineering, 4 YangtzeRiver Scholars and 4 winners of the National Fund for Distinguished Young Scholars of China. The School has about 1,500 students, including about 560 undergraduates, 470 master degree candidates, 360 doctoral candidates and 150 engineering masters. The School has formed 13 distinctive teaching and research teams by compacting discipline orientation and integrating academic teams.
Objective: To investigate the expression of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) and the relationship with cell cycle profiles in ovarian cancer SK-OV-3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. Expression of P-gp and MRP was detected with flow cyt...

To identify an effective auxiliary therapy for epithelial ovarian cancer. Progesterone acetate given at 250 mg intramuscularly twice a week for 1 month followed by increased administration to 500 mg intramuscularly every two weeks for 3 years was used in combination with platinum based chemotherapy to treat patients with epithelial ovarian cancer a...

Zhou Botong realised that he had been tricked by Huang Yaoshi so he returned to Peach Blossom Island to demand an explanation from Huang. Huang Yaoshi was still embattled by the loss of his wife. Zhou Botong's confrontational attitude merely fuelled the anger and frustration in him. When Huang Yaoshi blamed Zhou Botong for his wife's death, Zhou retorted angrily that he had also suffered in a similar experience with Liu Ying. Huang Yaoshi and Zhou Botong started fighting but neither of them was able to defeat his opponent. Huang Yaoshi imprisoned Zhou Botong on his island by sealing all possible exit routes. Zhou Botong roamed the island and settled in a cave for the next 15 years. During that period of time, Huang Yaoshi and Zhou Botong taunted each other to fight and kept themselves occupied with their conflict. Their feud is resolved when Guo Jing visits the island and meets Zhou Botong.
Zhiyuan College The Zhiyuan College, established in January 2010, offers “Zhiyuan Honors Program” to the top 5% SJTU undergraduates. Today, Zhiyuan has seven undergraduate programs: Mathematics, Physics, Life Science, Computer Science, Chemistry, Engineering and Biomedical Science. Aiming at cultivating top-notch talents into international academic masters, Zhiyuan College has recruited a group of eminent scholars from around the world to build first-class faculty team. Each year, Zhiyuan admits 350 students and there are 433 alumni worldwide currently, 90% of whom are pursuing further studies at top domestic and international universities and institutions. In addition to having a strong academic record, students who show a strong interest and the potential to pursue a research career are selected. In 2014, the talent training model of Zhiyuan College won the first-class award of “National Teaching Achievement Award”; and in 2016, “Zhiyuan Model” won “Cultivating Curiosity Award” and “Natural Sciences Award” of “Reimagine Education 2016”, which is jointly hosted by Wharton School of the University of Pennsylvania and QS—international institution for world university rankings on education.
To study the expression of the human novel gene NM23-H1B in ovarian cancer. Forty-eight samples from patients with ovarian tumor at different clinical stages and 8 from normal ovaries were examined for NM23-H1B mRNA expression by using RT-PCR, northern blot and in situ hybridization. All samples expressed NM23-H1B mRNA through RT-PCR, while the lev...
... In vEDS cells, an ER perturbation was suggested by the abnormal ER distribution of the protein disulfide isomerase enzyme and by reduced expression of FKBP22, an ER resident peptidyl-prolyl cis-trans-ER isomerase involved in the folding of COLLIII triple helix [108,139,140]. Since the perturbed ER redox state may influence the down-regulation of Bcl-2 and the activation of the caspase-dependent apoptosis [141], and FKBP22 can have an anti-apoptotic role acting on the expression of Bcl-2 and caspases [142], this aspect merits further studies in vEDS fibroblasts. ...
China Huiyuan Juice Group Limited (Chinese: 中国汇源果汁集团有限公司; pinyin: Zhōngguó Huìyuán Guǒzhī Jítuán Yǒuxiàn Gōngsī) (SEHK: 1886), established in 1992 and headquartered in Beijing, is the largest privately owned juice producer in China.[1] It is engaged in the manufacture and sales of juice and other beverage products. Its products include fruit juice and vegetable juice, nectars, bottled water, tea, and dairy drinks.[2]

The university's School of International Education is located here, where a large number of international students take classes throughout the academic year (however, most international students that take degree courses are in Minhang campus). The campus still houses a variety of scientific research institutions, State Key Laboratory of Ocean Engineering for instance, although most moved to the new campus since 1987.
Chemoresistance is the major obstacle to cure endometrial cancer, whereas metformin has demonstrated sensitization to chemotherapy in endometrial cancer. A novel finding states that isocitrate dehydrogenase 1 (IDH1) involves in cancer chemoresistance. Recent studies have revealed that epigenetic modifications facilitate chemoresistance. However, wh...
Golgi phosphoprotein 3 (GOLPH3), a newly recognized oncogene, is associated with tumor growth, metastasis, and poor prognosis in several types of cancer. However, its biological role and underlying mechanism in epithelial ovarian cancer (EOC) remain poorly understood. Here, we found that GOLPH3 was overexpressed in EOC tissues and cell lines. This...
UM-SJTU Joint Institute The UM-SJTU Joint Institute (JI) was jointly established in 2006 by two premier universities, the University of Michigan and Shanghai Jiao Tong University. The mission of JI is to build a world-class educational and research institute in China and foster future researchers and leaders with a global perspective. Abiding by the philosophy of “Internationalization, Interdisciplinary, Innovation, and Quality”, JI adopts curriculums blending the unique features of the two founding universities. Both of its undergraduate majors, Mechanical Engineering (ME) and Electrical & Computer Engineering (ECE), achieved the world’s most authoritative ABET accreditation. All courses are taught in English by world-class faculty recruited from global leading universities in the U.S. and other developed countries. Many are winners of prestigious awards such as Yangtze Scholar, 1000-talent Scholars, New Century Talents, Pujiang Scholars, and Shanghai Magnolia Gold and Silver Awards. JI has won many awards for higher education innovation, including the “Model of Chinese Higher Education Reform” from the Chinese State Council and the “Andrew Heiskell Award for Innovation in Higher Education” from the Institute of International Education, one of the most prestigious awards in international education.
... In vEDS cells, an ER perturbation was suggested by the abnormal ER distribution of the protein disulfide isomerase enzyme and by reduced expression of FKBP22, an ER resident peptidyl-prolyl cis-trans-ER isomerase involved in the folding of COLLIII triple helix [108,139,140]. Since the perturbed ER redox state may influence the down-regulation of Bcl-2 and the activation of the caspase-dependent apoptosis [141], and FKBP22 can have an anti-apoptotic role acting on the expression of Bcl-2 and caspases [142], this aspect merits further studies in vEDS fibroblasts. ...
... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...
... Mediator complex subunit 19 (MED19) is a member of the mediator that has a key role in the activation and repression of signal transduction or the regulation of transcription in carcinomas ( Casamassimi and Napoli, 2007;Sun et al, 2011). Accumulating evidence has shown that MED19 has important roles in cancer cell proliferation and tumorigenesis, and suppression of MED19 expression induces inhibition of cell proliferation and tumorigenesis in several different tumour types including lung cancer, pancreatic cancer, ovarian cancer and breast cancer ( Liu et al, 2012;Wei et al, 2015). Then we speculated that miR-214 played tumorigenic role by its target MED19 in CRC. ...
Shanghai Jiao Tong University (SJTU; Chinese: 上海交通大学) is a major research university in Shanghai. Established on April 8, 1896 as Nanyang Public School by an imperial edict issued by the Guangxu Emperor, it has been referred to as "The MIT of the East" since the 1930s.[5][6][7] It is renowned as one of the oldest, most prestigious and selective universities in China. Shanghai Jiao Tong is a C9 League university and a Chinese Ministry of Education Class A Double First Class University.[8]
In the same year, Feng Heng was pregnant with Huang Rong. When she learnt that the copy she wrote had been stolen, she attempted to write another from memory for her husband. However, the stress was too much for her to bear so she died shortly after giving birth to Huang Rong. Huang Yaoshi was deeply tramautised by the loss of his wife and driven to near-insanity. He vented his anger on his other four apprentices (Qu Lingfeng, Lu Chengfeng, Wu Mianfeng and Feng Mofeng) by crippling them and banishing them from his island.
Estrogen and progestin are involved in ovarian carcinogenesis. Change in nm23-H1 expression and the PIK3/AKT pathway are involved in carcinogenesis, development, invasion and metastasis of ovarian cancers. Therefore, it is critical to understand the signaling pathways that regulate hormone-induced cell migration and invasion in ovarian cancer. We i...

In 1945, after the defeat of the Japanese in the Second World War, he returned his hometown and joined a militia. He once took part in the battle of liberating Boshan District. Jiao Yulu joined the Communist Party of China in January 1946, and he soon was transferred to Bohai, Shandong and appointed a group leader of the Land Reform movement. By late Chinese Civil War, he worked in Weishi County, Henan province until 1951. In June 1953, he was transferred to Luoyang Mine Machine Manufacturing Plant and worked there until 1962.
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