Pyruvate kinase (PK) is a key enzyme in the process of glycolysis, catalyzing phosphoenolpyruvate (PEP) into pyruvate. Currently, PK isozyme type M2 (PKM2), one subtype of PK, has been proposed as a new tumor marker with high expression in various tumor tissues. Here we aimed to explore the effects of siRNAPKM2 on ovarian carcinoma (OC) cell lines...
To establish a sprouting embryoid body model mimicking early embryonic vasculogenesis in human embryo. Human embryonic stem were (hESCs) were cultured on the mouse embryo fibroblasts and then were induced to differentiate to form three-dimensional EB. The hEBs were cultured in media containing various angiogenesis-related factors: vascular endothel...

Zhou Botong realised that he had been tricked by Huang Yaoshi so he returned to Peach Blossom Island to demand an explanation from Huang. Huang Yaoshi was still embattled by the loss of his wife. Zhou Botong's confrontational attitude merely fuelled the anger and frustration in him. When Huang Yaoshi blamed Zhou Botong for his wife's death, Zhou retorted angrily that he had also suffered in a similar experience with Liu Ying. Huang Yaoshi and Zhou Botong started fighting but neither of them was able to defeat his opponent. Huang Yaoshi imprisoned Zhou Botong on his island by sealing all possible exit routes. Zhou Botong roamed the island and settled in a cave for the next 15 years. During that period of time, Huang Yaoshi and Zhou Botong taunted each other to fight and kept themselves occupied with their conflict. Their feud is resolved when Guo Jing visits the island and meets Zhou Botong.

Human embryonic stem (hES) cells are able to give rise to a variety of cell lineages under specific culture condition. An effective strategy for stable genetic modification in hES cells may provide a powerful tool for study of human embryogenesis and cell-based therapies. However, gene silences are documented in hES cells. In current study, we inve...
The college achieved world renown in the 1930s, and was referred to as the "Eastern MIT".[9] In 1938, the Ministry of Education assumed administration of the university and renamed it to National Chiao Tung University (Chinese: 國立交通大學), the name by which daughter institution National Chiao Tung University in Taiwan, is known to this day. In 1943, the graduate school was founded.
School of Aeronautics and Astronautics The School of Aeronautics and Astronautics (SAA) is the main body of SJTU to cultivate talents for aerospace. The school consist of 3 departments and 2 research centers, namely, Department of Aircraft Design, Department of Aerospace Information and Control, Department of Propulsion, Near Space Research Center and J.C. Wu Center of Aerodynamics. Currently, SAA has more than 60 faculty members, 15 professors/researchers, 28 associate professors/associate researchers, which includes 2 Academician of the Chinese Academy of Engineering, 3 National “1000 Plan” Scholars, 2 Cheung Kong Professor. The school has 72 Doctoral Candidates, 205 Master Candidates, 112 Undergraduate students and 38 international students. SAA has maintained close and wide-ranging research cooperation and academic exchanges with many famous overseas universities and research institutions. The school also engages in visionary research projects to meet future demands and train highly qualified aerospace professionals for the future development of the world’s aerospace industry.
Obesity is generally acknowledged as a risk factor for endometrial cancer, as accumulated adipocytes partly contribute to the increased production of estrogen which is involved in dysregulated cell growth and metastasis in early endometrial carcinogenesis. Thus we evaluated in this study expression of the fat mass and obesity-associated (FTO) gene...
Large amount of clinical evidence has demonstrated that insulin resistance is closely related to oncogenesis of endometrial cancer (EC). Despite recent studies showed the up-regulatory role of insulin in G protein-coupled estrogen receptor (GPER/GPR30) expression, GPER expression was not decreased compared to control when insulin receptor was block...
Snail, a key inducer of epithelial-mesenchymal transition (EMT), plays an important role in cancer metastasis. To better understand the role of Snail in the metastasis of ovarian carcinoma, expression of Snail was knocked down by antisense-Snail in the highly metastatic ovarian cancer cell line HO8910PM. Gene array analysis revealed that blocking S...
To assess the estrogen and progestin's effect on protein expression of metastasis repression gene nm23-H1 via regulation of phosphorylation signaling in epithelial ovarian cancer cell line ES-2. Ovarian clear cell adenocarcinom cell line ES-2 was treated by different doses of 17beta-estradiol (estrogen), medroxyprogestogen (progestin) and dimethyl...
Shortly after his marriage to Feng Heng, Huang Yaoshi met Wang Chongyang's junior, Zhou Botong. He learnt from Zhou Botong that Wang Chongyang had died and that Zhou had inherited the Nine Yin Manual. He wanted the book for himself so he tricked Zhou Botong into allowing his wife to read it. Zhou Botong agreed and let her read the second volume of the manual. Feng Heng had eidetic memory so she memorised the book easily. She lied to Zhou Botong that the manual was fake and that it was actually a copy of a book of childish rites she had memorised by heart. She recited the first few verses of the manual verbatim to Zhou Botong, who mistakenly believed her and destroyed the book in anger. After Zhou Botong left, Feng Heng wrote a copy of the manual from memory for her husband.
On February 13, 2004, Yuntai Mountain as the fifth in the world, the third in the country China, was named the world's first World Geopark by UNESCO and caused attention at home and abroad. Meanwhile, Yuntaishan is also a national scenic spot, National Civilized Scenic Area, the first national AAAAA-level scenic spot, national natural heritage, national forest parks, national macaque nature reserve. Yuntain Mountain also has Asia's highest head drop waterfall.
To investigate the effect of glycogen synthase kinase-3beta (GSK-3beta) on the proliferation of human ovarian cancer cells. Two human ovarian cancer cell lines SKOV3 and ES-2 were analysed for the expression of GSK-3beta and phosphorylated GSK-3beta (pGSK-3beta) by Western blot analysis. Cell growth curve analysis done by cell count was used to inv...
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
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