Human embryonic stem (hES) cells are able to give rise to a variety of cell lineages under specific culture condition. An effective strategy for stable genetic modification in hES cells may provide a powerful tool for study of human embryogenesis and cell-based therapies. However, gene silences are documented in hES cells. In current study, we inve...


To study the expression of the human novel gene NM23-H1B in ovarian cancer. Forty-eight samples from patients with ovarian tumor at different clinical stages and 8 from normal ovaries were examined for NM23-H1B mRNA expression by using RT-PCR, northern blot and in situ hybridization. All samples expressed NM23-H1B mRNA through RT-PCR, while the lev...
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
The Joint Institute has tuition-waived student exchange agreements with a several leading universities as well as various programs with the university of Michigan. If your university is a member of the Global E³ Network or you believe that your institution has an exchange agreement with Shanghai Jiao Tong University (SJTU), please contact your international programs office for information on how to apply.
School of International and Public Affairs School of International and Public Affairs (SIPA), established in 2003 and located I the heart of downtown Shanghai, has developed itself into one of the most influential and international schools in political science and public administration in China. It is ranked as a top ten public policy school in China by the Chinese Ministry of Education. SIPA consists of four departments: Department of Comparative Politics, Department of Public Administration, Department of International Relations and Department of Public Economics & Social Policy. The school offers both academic and professional degrees in political science and public administration, including one doctoral degree program, six master’s degree programs and one MPA program (Master of Public Administration). MPA program at SIPA is one of the first of its kind among Chinese universities and well-known for its mid-career education. Currently, over 1,500 students from across the globe study at SIPA. In addition, the school also trains public officials, including many mayors and local leaders.
A few highly aggressive and malignant tumor cells could acquire identities by turning on genes expressed by endothelial cells and recruit blood vessels to sustain tumor growth. Hypoxia was reported recently to play an essential role in these events. These 'plastic' tumor-cell phenotypes and the exact mechanism driving transendothelial differentiati...
In June 1962, he was appointed Communist Party Secretary of Weishi County. In December, he became the Second Communist Party Secretary of Lankao County. This region had declined into poverty and ignorance. The county had long been plagued by dust storms, waterlogging, and alkaline lands.[3] Jiao Yulu devoted his energies to fight economic backwardness. He mobilized the local residents to contend with the poor natural conditions. Due to years of toil, Jiao Yulu broke down from constant overwork and he was diagnosed with liver cancer. But he continued his struggle against natural disasters. On May 14, 1964, he died of liver cancer, aged 42.[3]
School of Physics and Astronomy The physics department of Shanghai Jiao Tong University was initially established in 1928, and was one of the earliest physics programs in China. Starting from 2007, the University made a strategic decision to rebuild a first-class physics program and started to invest newly on several subfields of physics, such as particle and nuclear physics, laser & plasma physics. After further incorporating astronomy and astrophysics in the year of 2016, the department was renamed the School of Physics and Astronomy. The School currently has now sixty-six full professors and forty-three distinguished research fellows which is equivalent to tenure track assistant professors in the US system. It has seven research institutes. The School sets up its mission to meet the Chinese national strategic demands in physical sciences and related interdisciplinary fields. It strives to establish a world-class research-education center of physical sciences that aim to solve scientific problems of substantial importance and to cultivate next generation of leading physicists. At present, the School covers two first-class disciplines of physics and astronomy. It has become one of the three most comprehensive physics schools in C-9 group, one of the four physics schools who boast national collaborative innovation research centers, and one of the first batch of six pilot institutes in Shanghai Jiao Tong University to build the world-class universities. It is acknowledged as one of the most competitive, fastest-growing, and comprehensive physics colleges in China.
To investigate the effects of follicle stimulating hormone (FSH) on the proliferation, apoptosis, migration and invasion of ovarian cancer cells. Ovarian cancer cells of the lines SKOV-3 and ES-2 were cultured, and treated by FSH of the concentrations of 10, 20, 40, 80, and 160 mU/ml for 48 h or 24 h respectively. The cells without FSH treatment we...
FKBP14 belongs to the family of FK506-binding proteins (FKBPs). Altered expression of FKBPs has been reported in several malignancies. This study aimed to reveal the expression profile of FKBP14 in ovarian cancer and evaluate whether FKBP14 is a molecular target for cancer therapy. We found that the FKBP14 mRNA level was significantly higher in ova...
School of Mechanical Engineering The history of the School of Mechanical Engineering (ME) , Shanghai Jiao Tong University (SJTU) dates back to 1913. The School has the vision of a world-class engineering school committed to high-level education and cutting edge research. It aims to offer the best learning experience to its students, the most rewarding working environment for its faculty and staff as well as the most effective service to industry and society. Among the 334 faculty members, 124 are professors, 152 are associate professors and 58 are assistant professors, and more than 5000 students are learning here. As one of the top Schools of Mechanical Engineering in China, it strives to increase its international competitiveness and global presence through quality teaching, advanced research and close collaboration with leading universities in the world. The alumni from the School, as scientists, engineers, educators, statesmen and entrepreneurs, always make outstanding contributions to the innovation of science and technology, and the development of the society.

Ovarian cancer is one of the most common cancers which cause female mortality. The knowledge of ovarian cancer initiation and progression is critical to develop new therapeutic strategies to treat and prevent it. Recently, SOX3 has been reported to play a pivotal role in tumor progression. However, the clinical significance of SOX3 in human ovarian...
... Furthermore, a report indicated that some kind of cervical cancer, such as minimal deviation adenocarcinoma, was not associated with high-risk HPV [25]. Qisang et al. [26] reported a significant positive correlation between positive hTERC gain and HR-HPV infection, histopathologic lesions (all P<0.01) in patients with cervical disease. Our study demonstrates that there are 23% HPV-infected positive cases in NNL, and 78.95% in CA group. ...
School of International and Public Affairs School of International and Public Affairs (SIPA), established in 2003 and located I the heart of downtown Shanghai, has developed itself into one of the most influential and international schools in political science and public administration in China. It is ranked as a top ten public policy school in China by the Chinese Ministry of Education. SIPA consists of four departments: Department of Comparative Politics, Department of Public Administration, Department of International Relations and Department of Public Economics & Social Policy. The school offers both academic and professional degrees in political science and public administration, including one doctoral degree program, six master’s degree programs and one MPA program (Master of Public Administration). MPA program at SIPA is one of the first of its kind among Chinese universities and well-known for its mid-career education. Currently, over 1,500 students from across the globe study at SIPA. In addition, the school also trains public officials, including many mayors and local leaders.

... Temserolimus was FDA approved for the treatment of advanced renal cell carcinoma in 2007 and is currently being evaluated in several clinical trials for its use in the treatment of gynecologic malignancies, including ovarian carcinoma.[28] Cell culture studies [10,293031 and mouse models323334353637 also suggested that PI3K pathway inhibitors are efficient in suppressing ovarian cancer cell growth. We analyzed the effect of the PI3K, AKT and mTORC1 inhibitors LY294002, SH-6 and rapamycin, respectively, on ovarian cancer cell growth using established cell lines and fresh human tumor tissue. ...


Luteinizing hormone (LH) plays an important role in the development of ovarian cancer, and has been shown to inhibit apoptosis in ovarian cancer cells. Similarly, survivin is a molecule that has been shown to inhibit apoptosis in other types of cancer. Therefore, the aim of this study was to determine whether survivin can be induced by LH in ovaria...
Recent studies have suggested that follicle-stimulating hormone (FSH) plays an important role in ovarian epithelial carcinogenesis. We demonstrated that FSH stimulates the proliferation and invasion of ovarian cancer cells, inhibits apoptosis, and facilitates neovascularisation. Our previous work has shown that transient receptor potential channel...
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