There is evidence to suggest that follicle-stimulating hormone (FSH) can facilitate the neovascularization of ovarian cancers by increasing vascular endothelial growth factor (VEGF) expression in cancer cells, although the underlying molecular mechanism of this process is not well known. Therefore, we investigated the effect of FSH on VEGF expressi...
To observe whether endothelial cell (EC) progenitors (CD(34)(+)-positive mononuclear cells) participated in neovasculogenesis of ovarian epithelial carcinoma through in vitro and in vivo experiments, and to explore the mechanism of tumor neovasculogenesis. CD(34)(+)-positive mononuclear cells were isolated from peripheral blood of ovarian epithelia...
Gankyrin has been implicated in the formation of multiple cancer types, although its roles in estrogen-driven endometrial carcinoma remain unclarified. We evaluated the expression of Gankyrin in endometrial tissues and further explored its roles in estrogen-driven and GPR30-mediated endometrial cancer cell proliferation. Gankyrin was overexpressed...
Department of Physical Education Established in 1986, the Physical Education Department of Shanghai Jiao Tong University is directly affiliated to the university. After more than 30 years of development, it has one first-level discipline authorized to offer master degree. There are 82 faculty members including 5 professors, 2 chair professors and 1 academic leader. It has been continuously awarded the "Presedent Cup" for seven times in national university games. The Department focuses on talent cultivation since the very beginning. By adhering to the "four combinations", the department will take teaching as the core, mass sport as the foundation, competition as the highlight and scientific research as the driving force. It will work actively to build the first-level platform with the characteristics of SJTU to cultivate talents by physical education.
Huiyuan (Chinese: 慧遠; Wade–Giles: Hui-yüan; 334–416 AD) was a Chinese Buddhist teacher who founded Donglin Temple on Mount Lushan in Jiangxi province and wrote the text On Why Monks Do Not Bow Down Before Kings in 404 AD. He was born in Shanxi province but after a long life of Buddhist teaching he wound up in Jiangxi province, where he died in 416. Although he was born in the north, he moved south to live within the bounds of the Eastern Jin Dynasty.
In 1945, after the defeat of the Japanese in the Second World War, he returned his hometown and joined a militia. He once took part in the battle of liberating Boshan District. Jiao Yulu joined the Communist Party of China in January 1946, and he soon was transferred to Bohai, Shandong and appointed a group leader of the Land Reform movement. By late Chinese Civil War, he worked in Weishi County, Henan province until 1951. In June 1953, he was transferred to Luoyang Mine Machine Manufacturing Plant and worked there until 1962.
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
Golgi phosphoprotein 3 (GOLPH3), a newly recognized oncogene, is associated with tumor growth, metastasis, and poor prognosis in several types of cancer. However, its biological role and underlying mechanism in epithelial ovarian cancer (EOC) remain poorly understood. Here, we found that GOLPH3 was overexpressed in EOC tissues and cell lines. This...
To investigate natural spontaneous menopausal age, menstruation span and their relationship with menarche age and parity in Pudong district of Shanghai. From Jan 2007 to Jul 2008, 15 083 spontaneous menopause women undergoing cervical cancer screening were enrolled in this study. The questionnaire included menarche age, parity, spontaneous menopaus...
To elucidate the mechanisms of nuclear estrogen receptor (ER)-mediated and G protein-coupled receptor 30 (GPR30)-mediated signaling in the regulation of proliferation in ER-positive and ER-negative endometrial cancer cells, two human endometrial carcinoma cell lines, Ishikawa (ER-positive) and KLE (ER-negative), were used. PCR and Western blot anal...
... Mediator complex subunit 19 (MED19) is a member of the mediator that has a key role in the activation and repression of signal transduction or the regulation of transcription in carcinomas ( Casamassimi and Napoli, 2007;Sun et al, 2011). Accumulating evidence has shown that MED19 has important roles in cancer cell proliferation and tumorigenesis, and suppression of MED19 expression induces inhibition of cell proliferation and tumorigenesis in several different tumour types including lung cancer, pancreatic cancer, ovarian cancer and breast cancer ( Liu et al, 2012;Wei et al, 2015). Then we speculated that miR-214 played tumorigenic role by its target MED19 in CRC. ...
Jiao Yulu was born in Yuanquan Town of Boshan District, in Zibo city, in Shandong province, to a poor family, on August 16, 1922, during the Republic of China.[3] Both his father Jiao Fangtian (焦方田) and mother were farmers.[3] He had only four years of schooling.[3] His father hanged himself during the Second Sino-Japanese War.[3] Jiao Yulu was conscripted into the Japanese labor and he was sent to coal-mining in Fushun, Liaoning, Manchoukuo.[3] He escaped to Suqian, Jiangsu in the fall of 1943.[3] He had been a farm labourer for two years for the landowner Hu Tairong (胡泰荣).[3]
Shortly after his marriage to Feng Heng, Huang Yaoshi met Wang Chongyang's junior, Zhou Botong. He learnt from Zhou Botong that Wang Chongyang had died and that Zhou had inherited the Nine Yin Manual. He wanted the book for himself so he tricked Zhou Botong into allowing his wife to read it. Zhou Botong agreed and let her read the second volume of the manual. Feng Heng had eidetic memory so she memorised the book easily. She lied to Zhou Botong that the manual was fake and that it was actually a copy of a book of childish rites she had memorised by heart. She recited the first few verses of the manual verbatim to Zhou Botong, who mistakenly believed her and destroyed the book in anger. After Zhou Botong left, Feng Heng wrote a copy of the manual from memory for her husband.
School of Mathematical Sciences The School of Mathematical Sciences (SMS) enjoys a rich history dating back to the establishment of Department of Mathematics in 1928, 32 years after the founding of the university. One evidence of its place in modern mathematics in China is that the first Congress of the Chinese Mathematical Society was held in 1935 at SJTU. In 2014, the Department of Mathematics was selected by the central government as one of the first four Model Schools for Internationalization, which encourages us to be more internationalization in its practices, vision and outlook. With the growth in size, it was reorganized into the School of Mathematical Sciences in December 2015. With more than 100 faculties members, the school now consists of 3 departments (Mathematics, Applied and Computational Mathematics, and Statistics) and 1 center (Research Center for Mathematics Education).
... Mediator complex subunit 19 (MED19) is a member of the mediator that has a key role in the activation and repression of signal transduction or the regulation of transcription in carcinomas ( Casamassimi and Napoli, 2007;Sun et al, 2011). Accumulating evidence has shown that MED19 has important roles in cancer cell proliferation and tumorigenesis, and suppression of MED19 expression induces inhibition of cell proliferation and tumorigenesis in several different tumour types including lung cancer, pancreatic cancer, ovarian cancer and breast cancer ( Liu et al, 2012;Wei et al, 2015). Then we speculated that miR-214 played tumorigenic role by its target MED19 in CRC. ...
Most buildings on campus were influenced by American architecture, while the main gate, which was built in 1935, is of traditional Chinese style reflecting the University's earlier status as the "Imperial Polytechnic College". The approaches to the main gate were via a series of marble bridges, similar to, although smaller than, those built in front of Tiananmen. However, recent road expansions have demolished the river as well as most of bridges. A copy of this famous gate scene have been built on the east of Minhang campus.
AAeronautics and AstronauticsAgriculture and BiologyAntai College of Economic and ManagementBBiomedical EngineeringCChemistry and Chemical EngineeringChina Europe International Business SchoolChina-UK Low Carbon CollegeEElectronic, Information and Electrical EngineeringEnvironmental Sciences and EngineeringFForeign LanguagesHHumanitiesIInternational and Public AffairsKKoGuan Law SchoolLLife Sciences and BiotechnologyMMarxismMaterials Science and EngineeringMathematical SciencesMechanical Engineering Media and DesignMedicineNNaval Architecture, Ocean and Civil EngineeringPPharmacyPhysical EducationPhysics and AstronomySShanghai Advanced Institute of FinanceSJTU-ParisTech Elite Institute of Technology U UM-SJTU Joint Institute USC-SJTU Institute of Cultural and Creative Industry Z Zhiyuan College
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring au...

Objective: To detect mRNA levels and expression of CD44, CD54, CD29 and E-cadherin (E-cad) and to discuss their relationship with formation and drug resistance of ovarian cancer SKOV3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. mRNA levels and expression of CD44, CD54, CD29 and E-cad...


School of Aeronautics and Astronautics The School of Aeronautics and Astronautics (SAA) is the main body of SJTU to cultivate talents for aerospace. The school consist of 3 departments and 2 research centers, namely, Department of Aircraft Design, Department of Aerospace Information and Control, Department of Propulsion, Near Space Research Center and J.C. Wu Center of Aerodynamics. Currently, SAA has more than 60 faculty members, 15 professors/researchers, 28 associate professors/associate researchers, which includes 2 Academician of the Chinese Academy of Engineering, 3 National “1000 Plan” Scholars, 2 Cheung Kong Professor. The school has 72 Doctoral Candidates, 205 Master Candidates, 112 Undergraduate students and 38 international students. SAA has maintained close and wide-ranging research cooperation and academic exchanges with many famous overseas universities and research institutions. The school also engages in visionary research projects to meet future demands and train highly qualified aerospace professionals for the future development of the world’s aerospace industry.
OCT4 plays a critical role in the maintenance of stem cell pluripotency and proliferation, and is overexpressed in multiple human tumors, including endometrial cancer. OCT4 expression can be modulated by miR-145 and the OCT4 pseudogene 5 (OCT4-pg5), which share similar binding sites in the OCT4 3'-untranslated region. The goal of the present study...
Genistein, the most abundant phytoestrogen in soybeans, may bind to estrogen receptors and perform anticancer activities. Choriocarcinoma is a malignant, trophoblastic and aggressive cancer of the placenta. Few studies are currently available concerning the effects of genistein on choriocarcinoma. In the present study, we investigated the effect of... 
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