To investigate the involvement of estrogen receptor (ER) beta in the proliferation of ovarian clear cell adenocarcinoma by restoring ERbeta expression in a cell line ES-2. A plasmid with full length ERbeta cDNA, pRSV-ERbeta and its negative vector control pRSV were introduced into ES-2. The cells transfected were named according to the plasmids: ES...
Our previous study revealed that estrogen regulates nm23-H1 expression thus promoting cell migration-invasion via activating PIK3/Akt pathway. In this study, we explored the effect of hormone on hypoxia-inducible factor-1 (HIF-1alpha), a key factor in cancer invasion and metastasis, via activation of Akt signaling transduction pathway. We treated t...
Luteinizing hormone (LH) plays an important role in the development of ovarian cancer, and has been shown to inhibit apoptosis in ovarian cancer cells. Similarly, survivin is a molecule that has been shown to inhibit apoptosis in other types of cancer. Therefore, the aim of this study was to determine whether survivin can be induced by LH in ovaria...
Background: Insulin resistance (IR) has been well studied in the initiation and development of endometrial endometrioid carcinoma (EEC). As yet, it has been largely neglected for estrogen sensitivity in local endometrium in hyperinsulinemia-induced systemic microenvironment. The aim of this study was to investigate the role of insulin in regulating...

Its population was 3,700,000 at the 2016 census whom 1,301,732 live in the built-up area made of 4 urban districts (Jiefang, Shanyang, Zhongzhan and Macun) and Bo'ai County being urbanized. Jiaozuo enjoys a humid subtropical climate with continental climate influences. Winters are cool and relatively dry while summers are hot and often rainy. Average temperature ranges from 0.3 °C in January to 27.5 °C in July. Extremes exist from -22.4 °C to 43.6 °C. Precipitation averages 659 mm.
Huang Yaoshi is very protective of his daughter and loves her with his life as she reminds him of his deceased wife. He imparts all his skills to her since she was a child and hoped to groom her to become his heir. When his daughter reaches adolescence, he decides to find a suitable husband for her. Ouyang Feng visits Peach Blossom Island with his nephew, Ouyang Ke, to propose a marriage between Ouyang Ke and Huang Rong. Huang Yaoshi favours Ouyang Ke and wants him to be his son-in-law. At the same time, Guo Jing also visits the island with his master, Hong Qigong. Hong Qigong nominates his apprentice to be Huang Yaoshi's son-in-law. Huang Yaoshi had met Guo Jing earlier at Guiyun Manor and wants to kill Guo to avenge Chen Xuanfeng.

Jiao Yulu (16 August 1922 – 14 May 1964) was a Chinese politician. Jiao Yulu was a symbol of the honest Party cadre who devotes himself tirelessly to the Communist State.[1] Jiao Yulu was considered to be a glorious example - Mao Zedong's good student during the period of personal worship. After his death, a campaign to study Jiao Yulu's example was started in 1966. The aim of the campaign was to boost morale and to rally the people to work harder to overcome difficulties. Party members in particular were called upon to follow Jiao Yulu's example by conducting more research and investigations into local conditions, and learn from his leadership style.[2]

To investigate the inhibitory effects of Snail--a zinc finger transcription factor, anti-sense plasmid on the invasion of ovary carcinoma cell lines in vitro. Four human ovarian carcinoma cell lines ES-2, OVCAR3, HO8910, HO8910PM were analyzed for the expression of Snail and E-cadherin mRNA by RT-PCR. Then anti-Snail plasmid transfection was introd...
Huang Yaoshi is very protective of his daughter and loves her with his life as she reminds him of his deceased wife. He imparts all his skills to her since she was a child and hoped to groom her to become his heir. When his daughter reaches adolescence, he decides to find a suitable husband for her. Ouyang Feng visits Peach Blossom Island with his nephew, Ouyang Ke, to propose a marriage between Ouyang Ke and Huang Rong. Huang Yaoshi favours Ouyang Ke and wants him to be his son-in-law. At the same time, Guo Jing also visits the island with his master, Hong Qigong. Hong Qigong nominates his apprentice to be Huang Yaoshi's son-in-law. Huang Yaoshi had met Guo Jing earlier at Guiyun Manor and wants to kill Guo to avenge Chen Xuanfeng.
School of Physics and Astronomy The physics department of Shanghai Jiao Tong University was initially established in 1928, and was one of the earliest physics programs in China. Starting from 2007, the University made a strategic decision to rebuild a first-class physics program and started to invest newly on several subfields of physics, such as particle and nuclear physics, laser & plasma physics. After further incorporating astronomy and astrophysics in the year of 2016, the department was renamed the School of Physics and Astronomy. The School currently has now sixty-six full professors and forty-three distinguished research fellows which is equivalent to tenure track assistant professors in the US system. It has seven research institutes. The School sets up its mission to meet the Chinese national strategic demands in physical sciences and related interdisciplinary fields. It strives to establish a world-class research-education center of physical sciences that aim to solve scientific problems of substantial importance and to cultivate next generation of leading physicists. At present, the School covers two first-class disciplines of physics and astronomy. It has become one of the three most comprehensive physics schools in C-9 group, one of the four physics schools who boast national collaborative innovation research centers, and one of the first batch of six pilot institutes in Shanghai Jiao Tong University to build the world-class universities. It is acknowledged as one of the most competitive, fastest-growing, and comprehensive physics colleges in China.
Huang Yaoshi is a loner who harbours unorthodox and heretical views on traditional Chinese rites and social norms. He is the master of Peach Blossom Island. Apart from being a formidable martial artist, he is also versed in other fields such as military strategy, music and divination. His eccentric personality causes him to be feared and shunned by others.
To investigate the effects of follicle stimulating hormone (FSH) on the proliferation, apoptosis, migration and invasion of ovarian cancer cells. Ovarian cancer cells of the lines SKOV-3 and ES-2 were cultured, and treated by FSH of the concentrations of 10, 20, 40, 80, and 160 mU/ml for 48 h or 24 h respectively. The cells without FSH treatment we...
School of Naval Architecture, Ocean and Civil Engineering The School of Naval Architecture, Ocean and Civil Engineering (NAOCE) has a strong tradition of excellence and is comprised of five departments: naval architecture and ocean engineering, engineering mechanics, civil engineering, architecture, and transportation and shipping logistics. It is the home of the State Key Laboratory of Ocean Engineering and the Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration. The naval architecture and ocean engineering program has been ranked No. 1 in 2017 Shanghai Ranking’s Global Ranking of Academic Subjects. The School also features two state key disciplines (Naval Architecture and Ocean Engineering; Mechanics). The School has 224 faculty members, including 78 professors and 90 associate professors. Among them, there are seven academicians of CAS and CAE, eight Thousand Talents Plan experts, six MOE Cheung Kong Scholars, and two NSFC distinguished young researchers.
In 1896, the Nanyang Public School (南洋公學) was founded in Shanghai by the imperial edict of the Guangxu Emperor, under the Business and Telegraphs Office of the Qing imperial government. Four schools were established: a normal school, a school of foreign studies, a middle school, and a high school. Sheng Xuanhuai, the mandarin who proposed the idea to the Guangxu Emperor, became the first president and is, along with missionary educator John Calvin Ferguson, regarded as the founder of the university.
Objective: To investigate the expression of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) and the relationship with cell cycle profiles in ovarian cancer SK-OV-3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. Expression of P-gp and MRP was detected with flow cyt...
The aim of present study was to investigate the role of preoperative neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) used as prognostic markers for predicting chemotherapeutic response and survival outcomes in patients with epithelial ovarian cancer (EOC) who are receiving platinum-based chemotherapy. A total of 344 pati...
The construction of the campus never came to an end in the past century. Existing buildings: the Middle College building (built in 1898), the original library (built in 1919), the gymnasium (built in 1925), the administrative building (built in 1933), the Xinjian building (built in 1953), the new Upper College building (built in 1955), the second teaching building (built in 1960), Bao Zhaolong library (built in 1985) and Haoran high-tech building (built in 1996) were constructed one after another.
Epithelial ovarian cancer (EOC) remains the most lethel gynecological malignancy. In the absence of an effective screening strategy, two thirds of patients are diagnosed in advanced clinical stage. Despite chemotherapy with cisplatin and paclitxel, primary or acquired chemoresistance faciltates survival of cancer cells, resulting in disease recurre...
Objective To assess the effect of 17β-estradiol(E2) on cell proliferation, cell invasiveness and its regulation of MTA3, Snail and matrix metalloproteinase 2 (MMP-2) expression in the ovarian clear cell adenocarcinoma cell line ES2, and to further investigate the mechanism involved. Methods We first investigated expression of ERα, ERβ, PR and E-cad...

Genistein, the most abundant phytoestrogen in soybeans, may bind to estrogen receptors and perform anticancer activities. Choriocarcinoma is a malignant, trophoblastic and aggressive cancer of the placenta. Few studies are currently available concerning the effects of genistein on choriocarcinoma. In the present study, we investigated the effect of...
Huang Yaoshi later regrets bitterly for inflicting such a heavy punishment on his innocent apprentices. He sets off to find his daughter, who has left home after quarrelling with her father. He meets Mei Chaofeng at Guiyun Manor on Lake Tai, where Lu Chengfeng has settled down. He agrees that Mei Chaofeng has been duly punished since she has lost her sense of sight and her husband. He forgives her and asks her to find his other apprentices and bring them back to the manor so he can heal their legs. However, he never saw his other apprentices again: Chen Xuanfeng was killed by Guo Jing; Qu Lingfeng was killed by Shi Yanming; Wu Mianfeng died of illness; Feng Mofeng has become a blacksmith and is killed by Jinlun Guoshi in the sequel. Huang Yaoshi later accepts Lu Chengfeng's son, Lu Guanying, and Qu Lingfeng's daughter, Shagu, as his grand-apprentices.

Progesterone plays an important role in the regulation of normal endometrium function by binding to progesterone receptor (PR). In endometrial cancer, however, PR is always down-regulated. Previous reports showed that methylation in the promoter region of the PR gene may be responsible for PRB isoform repression. However, the CpG islands in the exo...


Objective: To detect mRNA levels and expression of CD44, CD54, CD29 and E-cadherin (E-cad) and to discuss their relationship with formation and drug resistance of ovarian cancer SKOV3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. mRNA levels and expression of CD44, CD54, CD29 and E-cad...
AAeronautics and AstronauticsAgriculture and BiologyAntai College of Economic and ManagementBBiomedical EngineeringCChemistry and Chemical EngineeringChina Europe International Business SchoolChina-UK Low Carbon CollegeEElectronic, Information and Electrical EngineeringEnvironmental Sciences and EngineeringFForeign LanguagesHHumanitiesIInternational and Public AffairsKKoGuan Law SchoolLLife Sciences and BiotechnologyMMarxismMaterials Science and EngineeringMathematical SciencesMechanical Engineering Media and DesignMedicineNNaval Architecture, Ocean and Civil EngineeringPPharmacyPhysical EducationPhysics and AstronomySShanghai Advanced Institute of FinanceSJTU-ParisTech Elite Institute of Technology U UM-SJTU Joint Institute USC-SJTU Institute of Cultural and Creative Industry Z Zhiyuan College
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