To determine the role of oestrogen receptor α (ERα) in the regulation of survivin expression by 17β-estradiol (E(2)) in ovarian cancer cells and to evaluate the mechanism of E(2) action on ovarian cancer cell migration. We performed RT-PCR and Western blot analysis to assess the expression of ERα in the ovarian cancer cell lines NIH:OVCAR-3 and SKO...
Its population was 3,700,000 at the 2016 census whom 1,301,732 live in the built-up area made of 4 urban districts (Jiefang, Shanyang, Zhongzhan and Macun) and Bo'ai County being urbanized. Jiaozuo enjoys a humid subtropical climate with continental climate influences. Winters are cool and relatively dry while summers are hot and often rainy. Average temperature ranges from 0.3 °C in January to 27.5 °C in July. Extremes exist from -22.4 °C to 43.6 °C. Precipitation averages 659 mm.

To make the competition for his daughter's hand-in-marriage a fair one, Huang Yaoshi sets a series of three tests for the two contestants: Guo Jing and Ouyang Ke. The first obstacle is a test of martial arts. Ouyang Feng spars with Guo Jing while Hong Qigong fights Ouyang Ke. Guo Jing wins the first bout but ties with Ouyang Ke in the subsequent round, which involves appreciation of a piece of music played by Huang Yaoshi. The last assessment is a test of memory, in which Huang Yaoshi produces an incomplete copy of the Nine Yin Manual, without identifying the book, and asks the two contestants to memorise the text and recite to him later. Guo Jing read the manual before so he recites fluently and defeats Ouyang Ke.
... These clinical and basic science studies therefore suggest that P4 might be useful as an adjunct treatment for ovarian cancer. In fact one study using a xenograph ovarian tumor model has shown that high doses of P4 enhance the apoptotic action of cisplatin [5], which is consistent with a very limited clinical trial data [6]. Unfortunately other trials in both animal and humans have been relatively unsuccessful (See review by Ho [2]). ...
A long-term treatment with progestin commonly results in progestin resistance in endometrial cancer. So, the aim of this study was to investigate the role of glyoxalase I (GloI), a mediator of chemotherapy resistance, in metformin reversal of progestin resistance in endometrial carcinoma. The proliferation variety of endometrial cancer cells was de...
KoGuan Law School Legal education at Shanghai Jiao Tong University can be traced back to special and political classes during the period of Nanyang College in September 1901. However, it was interrupted during the education reform in 1950s until the Law School was re-established on June 8 2002. The law School received the new title “KoGuan School of Law” in 2008 in memorial of the generous donation of Professor Leo KoGuan. KoGuan School of Law has a strong, well-structured and international team of faculty, including 65 full-time faculty members. A variety of research centers within the law school has produced high quality scholarship covering a wide range of fields and disciplines, from constitutional law to law and society, from maritime law to competition law, etc. KoGuan School of Law has explored its own style of educating a new generation of law students and future jurists, and established its own reputation in both academic and practical circles. For the time being, it offers a full-scale legal education system including LLB, LLM, JM, and PhD programs.
OCT4 plays a critical role in the maintenance of stem cell pluripotency and proliferation, and is overexpressed in multiple human tumors, including endometrial cancer. OCT4 expression can be modulated by miR-145 and the OCT4 pseudogene 5 (OCT4-pg5), which share similar binding sites in the OCT4 3'-untranslated region. The goal of the present study...
Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events that lead to progestin resistance and to find a possible way to reverse progestin resistance in endometrial cancer, we established a progestin-resistant Ishikawa cell line by long-term progestin trea...
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells. It offers a promising therapeutic method against ovarian cancer. Endothelial progenitor cells (EPCs) could home to tumor lesion, and take part in angiogenesis. This study was to observe antitumo...
School of Chemistry and Chemical Engineering School of Chemistry and Chemical Engineering (SCCE) has a glorious history dating back to 1928. Inspired by the mottos “Prudence, Pragmaticality, Erudition, Innovation” at SCCE, we have been highly successful in the development of academic disciplines, research, and education excellence. After years of efforts, we have so far more than 160 faculty members, among whom there are four academicians of the Chinese Academy of Science, two chair professors supported by the “Thousand Talents Program”, and 11 experts supported by the “Thousand Young Talents Program”; a large number of scholars are supported by the National Science Fund for Distinguished Young Scholars, the “Cheung Kong Scholars Program”, the “National 973 Project”, the “National Science Fund for Outstanding Scholars”, etc. We provide comprehensive education programs including three undergraduate programs, four postgraduate programs(two master and two Ph.D. programs), visiting student programs and post-doctoral programs. With its energetic faculty and various education programs, SCCE has been considered as one of the long-standing educators in the field of chemistry and chemical engineering in China.
Jiao Yulu (16 August 1922 – 14 May 1964) was a Chinese politician. Jiao Yulu was a symbol of the honest Party cadre who devotes himself tirelessly to the Communist State.[1] Jiao Yulu was considered to be a glorious example - Mao Zedong's good student during the period of personal worship. After his death, a campaign to study Jiao Yulu's example was started in 1966. The aim of the campaign was to boost morale and to rally the people to work harder to overcome difficulties. Party members in particular were called upon to follow Jiao Yulu's example by conducting more research and investigations into local conditions, and learn from his leadership style.[2]
... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...
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