Ovarian cancers are heterogeneous and contain stem-like cells that are able to self-renew and are responsible for sustained tumor growth. Metastasis in peritoneal cavity occurs more frequently in ovarian cancer than in other malignancies, but the underlying mechanism remains largely unknown. We have identified that ovarian cancer stem-like cells (C...
To study the expression of glucose transporter-1 (GLUT1) and its correlation with basic fibroblast growth factor (bFGF) and proliferating cell nuclear antigen (PCNA) in epithelial ovarian neoplasm. Streptavidin-peroxidase complex technique was used to examine the expression of GLUT1, bFGF and PCNA protein in six cases of normal ovarian tissue, 20 c...
Huang Yaoshi is a loner who harbours unorthodox and heretical views on traditional Chinese rites and social norms. He is the master of Peach Blossom Island. Apart from being a formidable martial artist, he is also versed in other fields such as military strategy, music and divination. His eccentric personality causes him to be feared and shunned by others.
Jiaozuo is noted for its blast furnaces and machine construction industries. The total GDP of the city in 2017 was 234.28 billion yuan, an increase of 7.4% over the previous year. Among them, the added value of the primary industry was 13.733 billion yuan, up 4.6%; the added value of the secondary industry was 13.841 billion yuan, up 6.7%; the added value of the tertiary industry was 81.143 billion yuan, up 9.1%. The per capita GDP reached 65,936 yuan. The three industrial structures changed from 6.4:59.3:34.3 of 2016 to 5.9:59.5:34.6.link
Pyruvate kinase (PK) is a key enzyme in the process of glycolysis, catalyzing phosphoenolpyruvate (PEP) into pyruvate. Currently, PK isozyme type M2 (PKM2), one subtype of PK, has been proposed as a new tumor marker with high expression in various tumor tissues. Here we aimed to explore the effects of siRNAPKM2 on ovarian carcinoma (OC) cell lines...

To assess the estrogen and progestin's effect on protein expression of metastasis repression gene nm23-H1 via regulation of phosphorylation signaling in epithelial ovarian cancer cell line ES-2. Ovarian clear cell adenocarcinom cell line ES-2 was treated by different doses of 17beta-estradiol (estrogen), medroxyprogestogen (progestin) and dimethyl...
Early detection and monitoring the treatment remain the most important factors in improving long-term survival of ovarian cancer patients. New biomarkers that individually or in combination improve the diagnostic performance of existing tumor markers are critically needed. This study uses proteomic approaches to identify new biomarkers for detectio...
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells. It offers a promising therapeutic method against ovarian cancer. Endothelial progenitor cells (EPCs) could home to tumor lesion, and take part in angiogenesis. This study was to observe antitumo...

China Europe International Business School China Europe International Business School (CEIBS), a joint-venture for management education, was co-founded by the Chinese government and European Union (EU) in 1994, with Shanghai Jiao Tong University and the EFMD serving as its executive partners. As China's only business school to originate from government-level collaboration, CEIBS is committed to educating responsible leaders versed in "China Depth, Global Breadth" in line with its motto of "Conscientiousness, Innovation and Excellence". Leaders from the Chinese central government and the EU have respectively lauded CEIBS as "a cradle of excellent executives" and "a role model of EU-China cooperation". CEIBS offers MBA, EMBA, Global EMBA, Finance MBA and Executive Education programmes. Renowned for its academic rigour, CEIBS is the first business school on the Chinese mainland to have been accredited by both EQUIS and AACSB and the only business school in Asia to have simultaneously made it to the Financial Times' top 30 list of MBA, EMBA and Executive Education programmes. 

Recent studies have suggested that follicle-stimulating hormone (FSH) plays an important role in ovarian epithelial carcinogenesis. We demonstrated that FSH stimulates the proliferation and invasion of ovarian cancer cells, inhibits apoptosis, and facilitates neovascularisation. Our previous work has shown that transient receptor potential channel...
The construction of the campus never came to an end in the past century. Existing buildings: the Middle College building (built in 1898), the original library (built in 1919), the gymnasium (built in 1925), the administrative building (built in 1933), the Xinjian building (built in 1953), the new Upper College building (built in 1955), the second teaching building (built in 1960), Bao Zhaolong library (built in 1985) and Haoran high-tech building (built in 1996) were constructed one after another.
Huang Yaoshi is a loner who harbours unorthodox and heretical views on traditional Chinese rites and social norms. He is the master of Peach Blossom Island. Apart from being a formidable martial artist, he is also versed in other fields such as military strategy, music and divination. His eccentric personality causes him to be feared and shunned by others.
There is evidence to suggest that follicle-stimulating hormone (FSH) can facilitate the neovascularization of ovarian cancers by increasing vascular endothelial growth factor (VEGF) expression in cancer cells, although the underlying molecular mechanism of this process is not well known. Therefore, we investigated the effect of FSH on VEGF expressi...
China Europe International Business School China Europe International Business School (CEIBS), a joint-venture for management education, was co-founded by the Chinese government and European Union (EU) in 1994, with Shanghai Jiao Tong University and the EFMD serving as its executive partners. As China's only business school to originate from government-level collaboration, CEIBS is committed to educating responsible leaders versed in "China Depth, Global Breadth" in line with its motto of "Conscientiousness, Innovation and Excellence". Leaders from the Chinese central government and the EU have respectively lauded CEIBS as "a cradle of excellent executives" and "a role model of EU-China cooperation". CEIBS offers MBA, EMBA, Global EMBA, Finance MBA and Executive Education programmes. Renowned for its academic rigour, CEIBS is the first business school on the Chinese mainland to have been accredited by both EQUIS and AACSB and the only business school in Asia to have simultaneously made it to the Financial Times' top 30 list of MBA, EMBA and Executive Education programmes.

Objectives: The objective of this study was to analyze the relationship among the protein levels of MCM7, p63, and human papillomavirus (HPV) in different cervical lesion tissues and appraise their predictive value in evaluating severity of cervical disease. Methods: Twelve normal cervix or chronic cervicitis, 42 squamous intraepithelial lesions...
There is evidence to suggest that follicle-stimulating hormone (FSH) can facilitate the neovascularization of ovarian cancers by increasing vascular endothelial growth factor (VEGF) expression in cancer cells, although the underlying molecular mechanism of this process is not well known. Therefore, we investigated the effect of FSH on VEGF expressi...

Huang Yaoshi is married to Feng Heng and has six apprentices. He has scores of servants on his island, who are deaf and mute. Rumours in the jianghu say that he intentionally disabled them, but in fact, they were already mute and deaf before they became his servants. He recruited them as his servants to relieve them from the social stigma of their impairments so that they can enjoy a better life on his island. However, he does not wish to promote an image of himself as a kind and compassionate person so he spread those negative rumours about himself. Only his family and apprentices know the truth.
Because the activation of telomerase is a relatively early event in the progression of cervical carcinogenesis, the expression of the human telomerase RNA gene, TERC, has the potential to serve as a biomarker for both the diagnosis and prognosis of cervical neoplasias. In total, 83 research centers participated in the study, and 7786 patients were...
... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...
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