... Furthermore, a report indicated that some kind of cervical cancer, such as minimal deviation adenocarcinoma, was not associated with high-risk HPV [25]. Qisang et al. [26] reported a significant positive correlation between positive hTERC gain and HR-HPV infection, histopathologic lesions (all P<0.01) in patients with cervical disease. Our study demonstrates that there are 23% HPV-infected positive cases in NNL, and 78.95% in CA group. ...


Huiyuan (Chinese: 慧遠; Wade–Giles: Hui-yüan; 334–416 AD) was a Chinese Buddhist teacher who founded Donglin Temple on Mount Lushan in Jiangxi province and wrote the text On Why Monks Do Not Bow Down Before Kings in 404 AD. He was born in Shanxi province but after a long life of Buddhist teaching he wound up in Jiangxi province, where he died in 416. Although he was born in the north, he moved south to live within the bounds of the Eastern Jin Dynasty.
The pathogenesis of preeclampsia is unclear but is thought to be related to shallow trophoblast invasion. An invasive phenotype is acquired by trophoblasts through the process of epithelial-mesenchymal transition (EMT). We proposed that EMT in trophoblasts is deregulated in preeclampsia. The homeobox gene DLX4 plays an important role in epithelial-...
School of Agriculture and Biology School of Agriculture and Biology, established in 1959, has 5 departments including Food Science & Engineering, Resource and Environment, Landscape Architecture, Plant Sciences and Animal Sciences. Currently, the school has more than 1100 students and 147 full time faculties (143 doctors, 50 professors). It offers 5 bachelor degree subjects (Plant Science, Animal Science, Food Science and Engineering, Landscape Architecture, Resource and Environmental Science), 6 master degree subjects (Food Science and Engineering, Landscape Architecture, Horticulture, Ecology, Animal Husbandry, Agriculture Extension), and 5 doctoral degree subjects (Horticulture, Animal Science and Engineering, Food Science and Engineering, Ecology, Regional Planning and LA Design). The school has established close relationships with more than 30 world-renowned universities. It offers student exchange programs, 2+2 dual bachelor degree programs, joint PH.D programs, etc. The overall international co-operations in SAB provides students and faculties a wide internationalized platform for academic and research.

To observe whether endothelial cell (EC) progenitors (CD(34)(+)-positive mononuclear cells) participated in neovasculogenesis of ovarian epithelial carcinoma through in vitro and in vivo experiments, and to explore the mechanism of tumor neovasculogenesis. CD(34)(+)-positive mononuclear cells were isolated from peripheral blood of ovarian epithelia...


To observe whether endothelial cell (EC) progenitors (CD(34)(+)-positive mononuclear cells) participated in neovasculogenesis of ovarian epithelial carcinoma through in vitro and in vivo experiments, and to explore the mechanism of tumor neovasculogenesis. CD(34)(+)-positive mononuclear cells were isolated from peripheral blood of ovarian epithelia...
Objectives: The objective of this study was to analyze the relationship among the protein levels of MCM7, p63, and human papillomavirus (HPV) in different cervical lesion tissues and appraise their predictive value in evaluating severity of cervical disease. Methods: Twelve normal cervix or chronic cervicitis, 42 squamous intraepithelial lesions...
Epithelial ovarian cancer (EOC) remains the most lethel gynecological malignancy. In the absence of an effective screening strategy, two thirds of patients are diagnosed in advanced clinical stage. Despite chemotherapy with cisplatin and paclitxel, primary or acquired chemoresistance faciltates survival of cancer cells, resulting in disease recurre...
The college achieved world renown in the 1930s, and was referred to as the "Eastern MIT".[9] In 1938, the Ministry of Education assumed administration of the university and renamed it to National Chiao Tung University (Chinese: 國立交通大學), the name by which daughter institution National Chiao Tung University in Taiwan, is known to this day. In 1943, the graduate school was founded.
To investigate the involvement of estrogen receptor (ER) beta in the proliferation of ovarian clear cell adenocarcinoma by restoring ERbeta expression in a cell line ES-2. A plasmid with full length ERbeta cDNA, pRSV-ERbeta and its negative vector control pRSV were introduced into ES-2. The cells transfected were named according to the plasmids: ES...

School of Physics and Astronomy The physics department of Shanghai Jiao Tong University was initially established in 1928, and was one of the earliest physics programs in China. Starting from 2007, the University made a strategic decision to rebuild a first-class physics program and started to invest newly on several subfields of physics, such as particle and nuclear physics, laser & plasma physics. After further incorporating astronomy and astrophysics in the year of 2016, the department was renamed the School of Physics and Astronomy. The School currently has now sixty-six full professors and forty-three distinguished research fellows which is equivalent to tenure track assistant professors in the US system. It has seven research institutes. The School sets up its mission to meet the Chinese national strategic demands in physical sciences and related interdisciplinary fields. It strives to establish a world-class research-education center of physical sciences that aim to solve scientific problems of substantial importance and to cultivate next generation of leading physicists. At present, the School covers two first-class disciplines of physics and astronomy. It has become one of the three most comprehensive physics schools in C-9 group, one of the four physics schools who boast national collaborative innovation research centers, and one of the first batch of six pilot institutes in Shanghai Jiao Tong University to build the world-class universities. It is acknowledged as one of the most competitive, fastest-growing, and comprehensive physics colleges in China.
Pyruvate kinase (PK) is a key enzyme in the process of glycolysis, catalyzing phosphoenolpyruvate (PEP) into pyruvate. Currently, PK isozyme type M2 (PKM2), one subtype of PK, has been proposed as a new tumor marker with high expression in various tumor tissues. Here we aimed to explore the effects of siRNAPKM2 on ovarian carcinoma (OC) cell lines...

Objective: To investigate the expression of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) and the relationship with cell cycle profiles in ovarian cancer SK-OV-3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. Expression of P-gp and MRP was detected with flow cyt...
... These clinical and basic science studies therefore suggest that P4 might be useful as an adjunct treatment for ovarian cancer. In fact one study using a xenograph ovarian tumor model has shown that high doses of P4 enhance the apoptotic action of cisplatin [5], which is consistent with a very limited clinical trial data [6]. Unfortunately other trials in both animal and humans have been relatively unsuccessful (See review by Ho [2]). ...
School of Pharmacy SJTU School of Pharmacy was founded in 2000, and now it has 85 academic, administrative and technical staff members. The School has 17 research and teaching laboratories covering the complete spectrum of curriculum and disciplines of pharmacy education and research including medicinal chemistry, pharmacology, pharmaceutics, pharmaceutical microbiology & biochemistry, pharmacognosy, and traditional Chinese medicine. SJTU School of Pharmacy is a research-orientated institution. Its graduate student body, enrolled in Ph.D., M.Sc. and M.Eng. programs, is as twice larger as its undergraduate classes. Both of the undergraduate and graduate courses are given by individual research laboratories each consisting of a professor and two to four junior academic staffs. SJTU School of Pharmacy has not only developed scientific programs but also nurtured an educational and research environment that is liberal and innovation-orientated. The school has now become a leading institute and an ideal place for pharmacy education and pharmaceutical research in the nation.
Our previous study revealed that estrogen regulates nm23-H1 expression thus promoting cell migration-invasion via activating PIK3/Akt pathway. In this study, we explored the effect of hormone on hypoxia-inducible factor-1 (HIF-1alpha), a key factor in cancer invasion and metastasis, via activation of Akt signaling transduction pathway. We treated t...
The purpose of the study was to explore the role and mechanism of ataxia-telangiectasia mutated (ATM) protein in endometrial carcinogenesis. A reverse-phase protein array (RPPA) was used to analyze the expression of ATM signal pathway proteins in Ishikawa and progesterone-insensitive Ishikawa. ATM expression was detected in endometrium specimens by...
Recent studies have suggested that follicle-stimulating hormone (FSH) plays an important role in ovarian epithelial carcinogenesis. We demonstrated that FSH stimulates the proliferation and invasion of ovarian cancer cells, inhibits apoptosis, and facilitates neovascularisation. Our previous work has shown that transient receptor potential channel...
Genistein, the most abundant phytoestrogen in soybeans, may bind to estrogen receptors and perform anticancer activities. Choriocarcinoma is a malignant, trophoblastic and aggressive cancer of the placenta. Few studies are currently available concerning the effects of genistein on choriocarcinoma. In the present study, we investigated the effect of...
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