Ovarian cancer causes more deaths than any other type of female reproductive cancer. The development of new therapeutic approaches is required due to the low survival rate using routine methods. The goal of this study was to investigate the effect of the gene silencing of mediator complex subunit 19 (MED19) on cell viability and tumor growth in ova...
To identify an effective auxiliary therapy for epithelial ovarian cancer. Progesterone acetate given at 250 mg intramuscularly twice a week for 1 month followed by increased administration to 500 mg intramuscularly every two weeks for 3 years was used in combination with platinum based chemotherapy to treat patients with epithelial ovarian cancer a...
To make the competition for his daughter's hand-in-marriage a fair one, Huang Yaoshi sets a series of three tests for the two contestants: Guo Jing and Ouyang Ke. The first obstacle is a test of martial arts. Ouyang Feng spars with Guo Jing while Hong Qigong fights Ouyang Ke. Guo Jing wins the first bout but ties with Ouyang Ke in the subsequent round, which involves appreciation of a piece of music played by Huang Yaoshi. The last assessment is a test of memory, in which Huang Yaoshi produces an incomplete copy of the Nine Yin Manual, without identifying the book, and asks the two contestants to memorise the text and recite to him later. Guo Jing read the manual before so he recites fluently and defeats Ouyang Ke.
Early detection and monitoring the treatment remain the most important factors in improving long-term survival of ovarian cancer patients. New biomarkers that individually or in combination improve the diagnostic performance of existing tumor markers are critically needed. This study uses proteomic approaches to identify new biomarkers for detectio...
To establish a sprouting embryoid body model mimicking early embryonic vasculogenesis in human embryo. Human embryonic stem were (hESCs) were cultured on the mouse embryo fibroblasts and then were induced to differentiate to form three-dimensional EB. The hEBs were cultured in media containing various angiogenesis-related factors: vascular endothel...

The purpose of the study was to explore the role and mechanism of ataxia-telangiectasia mutated (ATM) protein in endometrial carcinogenesis. A reverse-phase protein array (RPPA) was used to analyze the expression of ATM signal pathway proteins in Ishikawa and progesterone-insensitive Ishikawa. ATM expression was detected in endometrium specimens by...
To study the expression of VEGF, KDR, MMP-1, and its transcription factor Ets-1 on the interstitial neovasculogenesis in human cervical carcinoma on molecular level, which may provide further theoretic bases on judgement of prognosis and explain interregularity between neovasculagenetic factors. VEGF, KDR, MMP-1, and Ets-1 were detected in 87 cervi...
×