... In vEDS cells, an ER perturbation was suggested by the abnormal ER distribution of the protein disulfide isomerase enzyme and by reduced expression of FKBP22, an ER resident peptidyl-prolyl cis-trans-ER isomerase involved in the folding of COLLIII triple helix [108,139,140]. Since the perturbed ER redox state may influence the down-regulation of Bcl-2 and the activation of the caspase-dependent apoptosis [141], and FKBP22 can have an anti-apoptotic role acting on the expression of Bcl-2 and caspases [142], this aspect merits further studies in vEDS fibroblasts. ...


China Huiyuan Juice Group Limited (Chinese: 中国汇源果汁集团有限公司; pinyin: Zhōngguó Huìyuán Guǒzhī Jítuán Yǒuxiàn Gōngsī) (SEHK: 1886), established in 1992 and headquartered in Beijing, is the largest privately owned juice producer in China.[1] It is engaged in the manufacture and sales of juice and other beverage products. Its products include fruit juice and vegetable juice, nectars, bottled water, tea, and dairy drinks.[2]

... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...


Genistein, the most abundant phytoestrogen in soybeans, may bind to estrogen receptors and perform anticancer activities. Choriocarcinoma is a malignant, trophoblastic and aggressive cancer of the placenta. Few studies are currently available concerning the effects of genistein on choriocarcinoma. In the present study, we investigated the effect of...
Objective: To investigate the chemosensitivity of ovarian cancer SK-OV-3ip1 multicellular aggregates (MCA) to cisplatin and taxol and to explore the possible mechanisms. Methods: Liquid overlay system was employed to obtain MCA. We detected the resistance using trypan blue exclusion testing, clonogenic assay, cell cycle profiles and apoptosis with...
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif...
On February 13, 2004, Yuntai Mountain as the fifth in the world, the third in the country China, was named the world's first World Geopark by UNESCO and caused attention at home and abroad. Meanwhile, Yuntaishan is also a national scenic spot, National Civilized Scenic Area, the first national AAAAA-level scenic spot, national natural heritage, national forest parks, national macaque nature reserve. Yuntain Mountain also has Asia's highest head drop waterfall.
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif... 

Huang Yaoshi is very protective of his daughter and loves her with his life as she reminds him of his deceased wife. He imparts all his skills to her since she was a child and hoped to groom her to become his heir. When his daughter reaches adolescence, he decides to find a suitable husband for her. Ouyang Feng visits Peach Blossom Island with his nephew, Ouyang Ke, to propose a marriage between Ouyang Ke and Huang Rong. Huang Yaoshi favours Ouyang Ke and wants him to be his son-in-law. At the same time, Guo Jing also visits the island with his master, Hong Qigong. Hong Qigong nominates his apprentice to be Huang Yaoshi's son-in-law. Huang Yaoshi had met Guo Jing earlier at Guiyun Manor and wants to kill Guo to avenge Chen Xuanfeng.
Albanian Leke 16American Dollars 53Argentine Pesos 43Australian Dollars 29Australian Pounds 15Austrian Schilling 27Bahraini Dinars 27Barbadian Dollars 18Belgian Francs 96Bosnia and Herzegovina convertible marks 29Brazilian Reais 26British Pounds 85Brunei Dollars 43Bulgarian Leva 45Canadian Dollars 59CFA francs Central Africa 10CFA francs West Africa 10CFP francs French Polynesia 15Chilean Pesos 22Chinese Yuan 49Colombian Pesos 12Croatian Kuna 23Cypriot Pounds 19Czech Koruna 34Danish Kroner 43Deutsche Marks 84Dutch Guilders 45Eastern Caribbean Dollars 34Egyptian Pounds 46Estonian Krooni 17Euros 21Falkland Islands Pounds 18Faroese Kronur 23Finnish Markkaa 25French Francs 92Georgian Lari 19Gibraltar Pounds 28Greek Drachmas 30Guernsey Pounds 22Hong Kong Dollars 117Hungarian Forints 28Icelandic Kronur 25Indian Rupees 33Indonesian Rupiah 27Irish Pounds 35Isle of Man Pounds 15Israeli New Sheqalim 21Italian Lire 37Jamaican Dollars 20Japanese Yen 30Jersey Pounds 29Jordanian Dinars 10Kuwaiti Dinars 37Latvian Lats 15Lithuanian Litu 24Luxembourgish Francs 14Macedonian Denari 19Malaysian Ringgit 52Maldivian Rufiyaa 15Maltese Lira 20Mexican Pesos 32Moldovan Lei 9Moroccan Dirhams 37New Taiwan Dollars 33New Zealand Dollars 41New Zealand Pounds 9Northern Irish Pounds 73Norwegian Kroner 25Omani Rials 14Peruvian Soles 17Philippine Peso 22Polish Zloty 50Portuguese Escudos 29Qatari Riyals 25Romanian Lei 11Romanian Old Lei 6Russian Rubles 38Saudi Riyals 26Scottish Pounds 69Serbian Dinara 26Singapore Dollars 58Slovak Koruna 13Slovenian Tolars 31South African Rands 44South Korean Won 37Spanish Pesetas 63Sri Lankan Rupees 55Swedish Kronor 38Swiss Francs 36Thai Baht 50Tunisian Dinars 5Turkish Lira 18Turkish Old Lira 15UAE Dirhams 25Ukrainian Hryvnia 30UncategorizedVietnamese Dong 26
School of Chemistry and Chemical Engineering School of Chemistry and Chemical Engineering (SCCE) has a glorious history dating back to 1928. Inspired by the mottos “Prudence, Pragmaticality, Erudition, Innovation” at SCCE, we have been highly successful in the development of academic disciplines, research, and education excellence. After years of efforts, we have so far more than 160 faculty members, among whom there are four academicians of the Chinese Academy of Science, two chair professors supported by the “Thousand Talents Program”, and 11 experts supported by the “Thousand Young Talents Program”; a large number of scholars are supported by the National Science Fund for Distinguished Young Scholars, the “Cheung Kong Scholars Program”, the “National 973 Project”, the “National Science Fund for Outstanding Scholars”, etc. We provide comprehensive education programs including three undergraduate programs, four postgraduate programs(two master and two Ph.D. programs), visiting student programs and post-doctoral programs. With its energetic faculty and various education programs, SCCE has been considered as one of the long-standing educators in the field of chemistry and chemical engineering in China.

Huang Yaoshi makes several brief appearances in the sequel. He rescues Cheng Ying from Li Mochou and accepts the child as his student. He develops a special bond with Yang Guo as both of them share the same distaste for the societal norms of their time, and he teaches Yang Guo two of his celebrated skills. Huang Yaoshi also participates in the defence of Xiangyang from Mongol invaders. At the end of the novel, he retains his original title as "Eastern Heretic" of the new "Five Greats" on Mount Hua, alongside Zhou Botong, Yang Guo, Guo Jing and Yideng.

To identify an effective auxiliary therapy for epithelial ovarian cancer. Progesterone acetate given at 250 mg intramuscularly twice a week for 1 month followed by increased administration to 500 mg intramuscularly every two weeks for 3 years was used in combination with platinum based chemotherapy to treat patients with epithelial ovarian cancer a...


To investigate the effects of sulindac metabolites on the proliferation and apoptosis of human umbilical vein endothelial cell line ECV304 in vitro. The proliferation of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. The cell cycle, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM) and electron mi...
Zhiyuan College The Zhiyuan College, established in January 2010, offers “Zhiyuan Honors Program” to the top 5% SJTU undergraduates. Today, Zhiyuan has seven undergraduate programs: Mathematics, Physics, Life Science, Computer Science, Chemistry, Engineering and Biomedical Science. Aiming at cultivating top-notch talents into international academic masters, Zhiyuan College has recruited a group of eminent scholars from around the world to build first-class faculty team. Each year, Zhiyuan admits 350 students and there are 433 alumni worldwide currently, 90% of whom are pursuing further studies at top domestic and international universities and institutions. In addition to having a strong academic record, students who show a strong interest and the potential to pursue a research career are selected. In 2014, the talent training model of Zhiyuan College won the first-class award of “National Teaching Achievement Award”; and in 2016, “Zhiyuan Model” won “Cultivating Curiosity Award” and “Natural Sciences Award” of “Reimagine Education 2016”, which is jointly hosted by Wharton School of the University of Pennsylvania and QS—international institution for world university rankings on education.
In the year 404, Huiyuan wrote a treatise On Why Monks Do Not Bow Down Before Kings (沙門不敬王者論).[4] This book symbolized his efforts to assert the political independence of Buddhist clergy from the courts of monarchic rulers. At the same time, it was a religious and political text that aimed to convince monarchs and Confucian-minded ministers of state that followers of Buddhism were ultimately not subversive. He argued that Buddhists could make good subjects in a kingdom due to their beliefs in retribution of karma and the desire to be reborn in paradise. Despite the Buddhists' reputation of leaving their family behind for a monastic life, Huiyuan stated "those who rejoice in the Way of the Buddha invariably first serve their parents and obey their lords."[1]
On February 13, 2004, Yuntai Mountain as the fifth in the world, the third in the country China, was named the world's first World Geopark by UNESCO and caused attention at home and abroad. Meanwhile, Yuntaishan is also a national scenic spot, National Civilized Scenic Area, the first national AAAAA-level scenic spot, national natural heritage, national forest parks, national macaque nature reserve. Yuntain Mountain also has Asia's highest head drop waterfall.

Progesterone plays an important role in the regulation of normal endometrium function by binding to progesterone receptor (PR). In endometrial cancer, however, PR is always down-regulated. Previous reports showed that methylation in the promoter region of the PR gene may be responsible for PRB isoform repression. However, the CpG islands in the exo...


School of Aeronautics and Astronautics The School of Aeronautics and Astronautics (SAA) is the main body of SJTU to cultivate talents for aerospace. The school consist of 3 departments and 2 research centers, namely, Department of Aircraft Design, Department of Aerospace Information and Control, Department of Propulsion, Near Space Research Center and J.C. Wu Center of Aerodynamics. Currently, SAA has more than 60 faculty members, 15 professors/researchers, 28 associate professors/associate researchers, which includes 2 Academician of the Chinese Academy of Engineering, 3 National “1000 Plan” Scholars, 2 Cheung Kong Professor. The school has 72 Doctoral Candidates, 205 Master Candidates, 112 Undergraduate students and 38 international students. SAA has maintained close and wide-ranging research cooperation and academic exchanges with many famous overseas universities and research institutions. The school also engages in visionary research projects to meet future demands and train highly qualified aerospace professionals for the future development of the world’s aerospace industry.
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells. It offers a promising therapeutic method against ovarian cancer. Endothelial progenitor cells (EPCs) could home to tumor lesion, and take part in angiogenesis. This study was to observe antitumo...
... With respect to other cancers, lithium has been found to be lethal to neuroblastoma cells but not to normal nerve cells (11). A similar effect was found in ovarian cancer cells (12), although a subsequent similar study on ovarian cancer cells suggests only a more modest benefit (13). It is not clear from our reading of the two ovarian cancer papers why the results are significantly different from each other. ...
Hello, I'm a student of mandarin Chinese, but only at a beginner level, I have a spoken exam tomorrow and I have written up what I want to say, however I'm not too sure its correct. Note: I haven't used tones on the letters, here's the text. please let me know I will be really grateful! This is what I want it to mean Good morning I am going to speak a little about my life I have 5 family members, mother father brother sister and myself. My mother is a dentist and my father is a business owner they are currently at work. my brother and my sister are both middle school students we live in Woking Surrey but my mother is milanese (italian) my father is (napoli italian) and i also was born in milan. my mom and i go to the solarium once a month. Woking is pretty and very big but has nothing to do at night. However the living habits are very interesting, like the yearly dance off. we go to the cinema, pop concerts and theater. i love going to restourants with my friends. we go to chinese restaurants, italian restaurants and american restaurants I have many hobbies, one of my friends is called prash. we practice kickboxing and kong fu every thursday on monday wednesday thursday and friday i go to uni. I use the train, there is no seats in the mornings but i very much love going to uni. im also a gamer, i own a team with four people. they are called B , Ray, Billy and Yougesh. B is my brother, ray is maltese, billy is english and yougesh is nepalese.We play League of legends, a game very famous in China. thank you for listening. CHINESE::::::: Zaochen hao! Wo yao shuo yi dian guanyu wo de shenghuo Wo jia you wu ge ren , baba mama didi meimei he wo. Wo mama shi yake yisheng he wo baba shi yewu jingli, nimen dou gongzuo xianzai. Wo didi he meimei dou shi zhong xue de xue sheng. Women zhu wojin zai Sali dan wo mama shi yidali Milan ren , baba shi yidali nabulesi ren he ye wo Milan chu sheng . wo he mama qu rengong riguangyu yi ge yue Wo jin shi xiangdang he hen da dan mei you shenme zuo de wangshang raner zher de shenghuo ziguan hen youyisi biru shuo meinian de dou wu. Women qu dianyingyuan, liuxing yinyuehui he juyian. Wo you henduo aihao Wo xihuan qu zai can ting yu wo pengyou. Women qu zhongguo can ting, yidali can ting he meiguo can ting mei yue yici Wo de yi ge pengyou jiao Prash. Women zuo taiquandao he gong fu fang xingqisi. Xingqiyi, xingqisan xingqisi he xingqiwu wo qu daxue wo zui huoche, zhaoshang zhe shi bu zuowei dan wo hen xihuan qu daxue. Wo shi wanjia, wo you yige tuandui you si ge ren. Tamen jiao B, Ray, Billy he Yougesh. B shi wo didi, Ray shi maertaren, billy shi yinguoren he yougesh shi niboren. Women wan yingxiong lianmeng, Zhege youxi hen shou huanying zai zhonguo. Xiexie nin ting THANK YOU to anyone who manages to help <3
To study the expression of the human novel gene NM23-H1B in ovarian cancer. Forty-eight samples from patients with ovarian tumor at different clinical stages and 8 from normal ovaries were examined for NM23-H1B mRNA expression by using RT-PCR, northern blot and in situ hybridization. All samples expressed NM23-H1B mRNA through RT-PCR, while the lev...
Previously, we demonstrated that follicle stimulating hormone (FSH) enhanced VEGF expression and facilitated ovarian cancer angiogenesis via the PI3K/AKT signaling pathway. In this study, we further investigated the involvement of microRNA-27a: ZBTB10‑specificity protein pathway in the mechanism of FSH-induced VEGF, Cox2 and survivin expression. Tr...
Ovarian cancer is the leading cause of death among gynecologic cancers and is the fifth leading cause of all cancer-related deaths among women. The development of novel molecular targets is therefore important to many patients. Recently, the SRY-related transcription factor SOX2 has been widely reported to be involved in multiple pathophysiological...
School of Media and Design Established in 2002, School of Media and Design (SMD) at Shanghai Jiao Tong University aims at educating a new generation of communication graduates who are not only equipped with critical thinking but also with creative capability. The School consists of four departments: Journalism & Communication, Film & Television, Design, and Cultural Industry & Management. To date, SMD has more than 90 faculty members. About 25% of them earned their doctoral degrees in the U.S., U.K., and other western countries. SMD also hosts more than 700 undergraduates, 300 master students, and 100 doctoral students. There are currently 324 international students in the school. Among them 104 are master or doctoral students who come from 55 countries including the U.S., U.K., France, Australia, Russia, South Korea, Pakistan etc. Many of them graduated from world prestigious universities like Princeton University, University of Chicago, University of South California and University of California-Los Angeles.
Chemoresistance is the major obstacle to cure endometrial cancer, whereas metformin has demonstrated sensitization to chemotherapy in endometrial cancer. A novel finding states that isocitrate dehydrogenase 1 (IDH1) involves in cancer chemoresistance. Recent studies have revealed that epigenetic modifications facilitate chemoresistance. However, wh...
School of Life Sciences and Biotechnology The School of Life Sciences and Biotechnology was jointly founded by Shanghai Jiao Tong University and the Chinese Academy of Sciences (Shanghai branch) in 1997. The 139 faculty members, including 51 full professors and 60 associate professors, are dedicated to cultivating diverse and unique talents in undergraduate students and postgraduate researchers. The School is also home to the State Key Laboratory of Microbial Metabolism and the Key Laboratory for Genetics Development and Neuropsychiatric Disorder. Our faculties, led by two prominent members of the Chinese Academy of Sciences, have earned numerous prestigious awards and international recognitions. By the 2017 ESI-based matrix, we ranked in the top 1% world-wide in Biology and Biochemistry, Molecular Biology and Genetics, Microbiology, and Plant and Animal Science. Hosting two state-level education bases, we administer a six-year combined bachelor-master program and an eight-year bachelor-master-PhD program. 1193 students are currently enrolled, including 303 undergraduates and 890 graduate students.
Huang Yaoshi makes several brief appearances in the sequel. He rescues Cheng Ying from Li Mochou and accepts the child as his student. He develops a special bond with Yang Guo as both of them share the same distaste for the societal norms of their time, and he teaches Yang Guo two of his celebrated skills. Huang Yaoshi also participates in the defence of Xiangyang from Mongol invaders. At the end of the novel, he retains his original title as "Eastern Heretic" of the new "Five Greats" on Mount Hua, alongside Zhou Botong, Yang Guo, Guo Jing and Yideng.
Jiao Yulu was born in Yuanquan Town of Boshan District, in Zibo city, in Shandong province, to a poor family, on August 16, 1922, during the Republic of China.[3] Both his father Jiao Fangtian (焦方田) and mother were farmers.[3] He had only four years of schooling.[3] His father hanged himself during the Second Sino-Japanese War.[3] Jiao Yulu was conscripted into the Japanese labor and he was sent to coal-mining in Fushun, Liaoning, Manchoukuo.[3] He escaped to Suqian, Jiangsu in the fall of 1943.[3] He had been a farm labourer for two years for the landowner Hu Tairong (胡泰荣).[3]
To assess the clinical features and prognostic factors of malignant ovarian teratoma. Eighty-four patients with malignant ovarian teratoma between 1954 and 2001 were studied retrospectively. All patients were treated with surgery, the mid-period of follow-up was 146 months. Patient characteristics, surgical therapy, pathologic diagnosis, histologic...
To compare the therapeutic and toxic profile of topotecan given intraperitoneally with intravenously in human ovarian cancer xenografted into athymic nude mice. Eighty female Balb-c/nu-nu mice were randomized assigned into eight groups (n=10). Xenografts resulted from intramesentery injection of cultured human ovarian cancer cells SKOV3 in athymic...
×