School of Life Sciences and Biotechnology The School of Life Sciences and Biotechnology was jointly founded by Shanghai Jiao Tong University and the Chinese Academy of Sciences (Shanghai branch) in 1997. The 139 faculty members, including 51 full professors and 60 associate professors, are dedicated to cultivating diverse and unique talents in undergraduate students and postgraduate researchers. The School is also home to the State Key Laboratory of Microbial Metabolism and the Key Laboratory for Genetics Development and Neuropsychiatric Disorder. Our faculties, led by two prominent members of the Chinese Academy of Sciences, have earned numerous prestigious awards and international recognitions. By the 2017 ESI-based matrix, we ranked in the top 1% world-wide in Biology and Biochemistry, Molecular Biology and Genetics, Microbiology, and Plant and Animal Science. Hosting two state-level education bases, we administer a six-year combined bachelor-master program and an eight-year bachelor-master-PhD program. 1193 students are currently enrolled, including 303 undergraduates and 890 graduate students.
... [9,25] Overall, the main reasons reported contributing to the psychosocial burden among women (anxious, fearful, self-blame, powerlessness, disbelief, depression, and anger) in this domain were lack of understanding of abnormal Pap smear results and higher perceived risk of developing cervical cancer which also have negative impact on perception of self. [10,11,26] Domain 3: Worry about human papillomavirus infectivity Women of reproductive age were found to have a significantly higher mean score not only in general but also in both individual items of this domain " worry about HPV infectivity " compared to a menopausal group of women. Our results were quite similar to the study conducted in the United States which reported that women with abnormal Pap smear results were distressed due to a sense of shame or guilt when they came to know that these cervical changes are associated with HPV and which is a sexually transmitted infection. ...
AAeronautics and AstronauticsAgriculture and BiologyAntai College of Economic and ManagementBBiomedical EngineeringCChemistry and Chemical EngineeringChina Europe International Business SchoolChina-UK Low Carbon CollegeEElectronic, Information and Electrical EngineeringEnvironmental Sciences and EngineeringFForeign LanguagesHHumanitiesIInternational and Public AffairsKKoGuan Law SchoolLLife Sciences and BiotechnologyMMarxismMaterials Science and EngineeringMathematical SciencesMechanical Engineering Media and DesignMedicineNNaval Architecture, Ocean and Civil EngineeringPPharmacyPhysical EducationPhysics and AstronomySShanghai Advanced Institute of FinanceSJTU-ParisTech Elite Institute of Technology U UM-SJTU Joint Institute USC-SJTU Institute of Cultural and Creative Industry Z Zhiyuan College
The purpose of the study was to explore the role and mechanism of ataxia-telangiectasia mutated (ATM) protein in endometrial carcinogenesis. A reverse-phase protein array (RPPA) was used to analyze the expression of ATM signal pathway proteins in Ishikawa and progesterone-insensitive Ishikawa. ATM expression was detected in endometrium specimens by...
Chemoresistance is the major obstacle to cure endometrial cancer, whereas metformin has demonstrated sensitization to chemotherapy in endometrial cancer. A novel finding states that isocitrate dehydrogenase 1 (IDH1) involves in cancer chemoresistance. Recent studies have revealed that epigenetic modifications facilitate chemoresistance. However, wh... 

SJTU-ParisTech Elite Institute of Technology The SJTU – ParisTech Elite Institute of Technology (SPEIT) brings together the strengths of leading French Grandes Ecoles (Ecole Polytechnique, Mines ParisTech, Telecom ParisTech, ENSTA ParisTech) and of Shanghai Jiao Tong University to develop Sino-French research and innovation collaboration and to educate high-potential Chinese and international students to become industrial leaders and innovators with: • a broad-based scientific background • the ability to evolve in a multicultural business environment • a forefront knowledge in one specialty field: Information and Communication Technology, Mechanical Engineering and Power and Energy Engineering. SPEIT enrolled its first students in 2012. In 2013, SPEIT was inaugurated by preceding French President, Mr François Hollande. In 2015, it got the accreditation of French Commission des Titres d’Ingénieurs and EUR-ACE: SPEIT graduates are awarded French titre d’ingénieur, which is internationally acknowledged as an equivalent to a Master in Engineering Science. In June 2016, SPEIT was granted an excellent Sino-French collaboration award by Chinese Vice-Prime Minister and French Minister of Education.
... ovarian diameter must be ≥ 31 mm. The presence of PFOs was evaluated binary, thereby the visualization of at least one side (unilateral)/individual was considered positive [129] . It has to be recognized that an PFO/ " PCO " is according to Netter (1990) [21] just a " clinical finding similar to splenomegaly or hepatomegaly ; cystic ovaries are found in a multiplicity of states, which have nothing in common etiologically; the clinical management varies and is dependent on the etiology " . ...
Snail, a key inducer of epithelial-mesenchymal transition (EMT), plays an important role in cancer metastasis. To better understand the role of Snail in the metastasis of ovarian carcinoma, expression of Snail was knocked down by antisense-Snail in the highly metastatic ovarian cancer cell line HO8910PM. Gene array analysis revealed that blocking S...
Henan Polytechnic University (HPU)[1], with a history of nearly 100 years, is the first mining university in Chinese history. Its former is Jiaozuo Coal Mining School which was established by the British Syndicate Co. Ltd., in 1909. It has changed its names several times in the course of development, namely, FuZhong Coal Mining University, Jiaozuo Private Institute of Technology, North-west Institute of Technology, Jiaozuo National Institute of Technology, Jiaozuo Mining Institute and Jiaozuo Institute of Technology. The University resumed its name of Henan Polytechnic University in 2004.
To elucidate the mechanisms of nuclear estrogen receptor (ER)-mediated and G protein-coupled receptor 30 (GPR30)-mediated signaling in the regulation of proliferation in ER-positive and ER-negative endometrial cancer cells, two human endometrial carcinoma cell lines, Ishikawa (ER-positive) and KLE (ER-negative), were used. PCR and Western blot anal...

Shanghai Jiao Tong University (SJTU; Chinese: 上海交通大学) is a major research university in Shanghai. Established on April 8, 1896 as Nanyang Public School by an imperial edict issued by the Guangxu Emperor, it has been referred to as "The MIT of the East" since the 1930s.[5][6][7] It is renowned as one of the oldest, most prestigious and selective universities in China. Shanghai Jiao Tong is a C9 League university and a Chinese Ministry of Education Class A Double First Class University.[8]

Ovarian cancer is the leading cause of death among gynecologic cancers and is the fifth leading cause of all cancer-related deaths among women. The development of novel molecular targets is therefore important to many patients. Recently, the SRY-related transcription factor SOX2 has been widely reported to be involved in multiple pathophysiological...
... Furthermore, a report indicated that some kind of cervical cancer, such as minimal deviation adenocarcinoma, was not associated with high-risk HPV [25]. Qisang et al. [26] reported a significant positive correlation between positive hTERC gain and HR-HPV infection, histopathologic lesions (all P<0.01) in patients with cervical disease. Our study demonstrates that there are 23% HPV-infected positive cases in NNL, and 78.95% in CA group. ...
School of Biomedical Engineering The School of Biomedical Engineering (BME) aims to satisfy the major needs of global development and meet the demand for interdisciplinary programs between medicine, science, and engineering. Based on the current frontiers of international research, major national needs, interdisciplinary programs, and the existing foundation of SJTU, BME consists the following six disciplines: Biomedical Instrumentation, Neuroscience and Engineering, Medical Imaging & Informatics, Nano-biomaterials, Systems Biology & Medicine, and Biological Sciences & Diseases. BME has been dedicated in cultivating high-level research, development, and management talents that are internationally competitive in the field of biomedical engineering.

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring au...

USC-SJTU Institute of Cultural and Creative Industry USC-SJTU Institute of Cultural and Creative Industry (ICCI) is jointly established by Shanghai Jiao Tong University (SJTU) and University of Southern California (USC). With supports from all aspects of the society, ICCI aims to develop itself into a pilot of international collaboration in the field of cultural and creative industry.When culture leads, creativity triumphs. Located in the economic and financial center of China and taking the revitalization of the country and the nation as its own mission, Shanghai Jiao Tong University has cultivated numerous elites in politics, science, industries and arts, and has made great contributions to the country’s economics, science and technology, arts, and health care since founded in 1896. There are a number of famous alumni such as Li Shutong (a master of culture and arts), Lu Yan (a Chinese Hollywood Actress), Hong Shen (a dramatist), and Zhu Qizhan (a famous painter). This manifests the great contribution SJTU has made to the culture and creative industry. University of Southern California is located in Los Angeles, the cultural capital of the world. It has enjoyed a long-lasting high reputation for cultivating a large number of elites in the cultural and creative industry.
Gestational diabetemellitus (GDM) is a condition whereby a mother's glucose tolerance is impaired with onset or first recognition during pregnancy which is not either type 1 or type 2 diabetes mellitus. Oxidative stress plays an essential role in diabetes, however, whether it also includes in GDM has not been fully clarified. Therefore, we investig...

USC-SJTU Institute of Cultural and Creative Industry USC-SJTU Institute of Cultural and Creative Industry (ICCI) is jointly established by Shanghai Jiao Tong University (SJTU) and University of Southern California (USC). With supports from all aspects of the society, ICCI aims to develop itself into a pilot of international collaboration in the field of cultural and creative industry.When culture leads, creativity triumphs. Located in the economic and financial center of China and taking the revitalization of the country and the nation as its own mission, Shanghai Jiao Tong University has cultivated numerous elites in politics, science, industries and arts, and has made great contributions to the country’s economics, science and technology, arts, and health care since founded in 1896. There are a number of famous alumni such as Li Shutong (a master of culture and arts), Lu Yan (a Chinese Hollywood Actress), Hong Shen (a dramatist), and Zhu Qizhan (a famous painter). This manifests the great contribution SJTU has made to the culture and creative industry. University of Southern California is located in Los Angeles, the cultural capital of the world. It has enjoyed a long-lasting high reputation for cultivating a large number of elites in the cultural and creative industry.
... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...
Huiyuan began studying the Zhuangzi and Laozi at a young age, as well as the teachings of Confucius. However, at the age of 21 he was converted in Hebei Province by the Buddhist Dao An, who was a Chinese disciple of a Kuchan missionary. Hearing the sermons of Dao An convinced Huiyuan to "leave the family" and embark on a life of Buddhist teachings.[1] Later, he became a patriarch of Donglin Temple (East Forest Temple) at Mount Lushan. His teachings were various, including the vinaya (戒律), meditation (禪法), abhidharma and Prajna or wisdom. Although Huiyuan did not take the initiative in establishing the relations with the secular world, he had contacts with court and gentry families. Huiyuan was on two occasions invited by the dictator Huan Xuan to take part in the discussions about the status of the clergy and Huiyuan defended the independence of the clergy. Members of the cultured classes came to live on Mount Lu as Huiyuan's lay disciples to take part in the religious life. Besides his teaching and interaction with lay followers of the Buddhist faith, he also upheld a learned correspondence with the monk Kumarajiva.[2]
Ovarian cancer causes more deaths than any other type of female reproductive cancer. The development of new therapeutic approaches is required due to the low survival rate using routine methods. The goal of this study was to investigate the effect of the gene silencing of mediator complex subunit 19 (MED19) on cell viability and tumor growth in ova...
Obesity is generally acknowledged as a risk factor for endometrial cancer, as accumulated adipocytes partly contribute to the increased production of estrogen which is involved in dysregulated cell growth and metastasis in early endometrial carcinogenesis. Thus we evaluated in this study expression of the fat mass and obesity-associated (FTO) gene...

Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events that lead to progestin resistance and to find a possible way to reverse progestin resistance in endometrial cancer, we established a progestin-resistant Ishikawa cell line by long-term progestin trea...
To assess the estrogen and progestin's effect on protein expression of metastasis repression gene nm23-H1 via regulation of phosphorylation signaling in epithelial ovarian cancer cell line ES-2. Ovarian clear cell adenocarcinom cell line ES-2 was treated by different doses of 17beta-estradiol (estrogen), medroxyprogestogen (progestin) and dimethyl...
Gestational diabetemellitus (GDM) is a condition whereby a mother's glucose tolerance is impaired with onset or first recognition during pregnancy which is not either type 1 or type 2 diabetes mellitus. Oxidative stress plays an essential role in diabetes, however, whether it also includes in GDM has not been fully clarified. Therefore, we investig...
School of Electronic, Information and Electrical Engineering The School of Electronic Information and Electrical Engineering (SEIEE) at Shanghai Jiao Tong University (SJTU) was established in 2001, with its glorious history traced back to 1908 when the discipline of Electric Machines was founded. With a century-long history of reputation in research and education, SEIEE is crowned as “the Cradle of Chinese Electrical Engineers”. The school now has 12 departments and principal units including the Department of Electrical Engineering, the Department of Automation, the Department of Computer Science and Engineering, the Department of Electronic Engineering, the Department of Instrument Science and Engineering, the Department of Micro-Nano Electronics, the School of Cyber Security, the School of Software, the Academy of Information Technology and Electrical Engineering, the Center for Advanced Electronic Materials and Devices, the Center for Teaching and Learning Development, and the Cooperative Medianet Innovation Center.
Since 2003, Shanghai Jiao Tong University has produced the Academic Ranking of World Universities[24] which analyzes the top universities in the world on quality of faculty (40%), research output (40%), quality of education (10%) and performance vs. size (10%).[25] Its ranking is exclusively of research universities, mainly in the empirical sciences.
Huiyuan began studying the Zhuangzi and Laozi at a young age, as well as the teachings of Confucius. However, at the age of 21 he was converted in Hebei Province by the Buddhist Dao An, who was a Chinese disciple of a Kuchan missionary. Hearing the sermons of Dao An convinced Huiyuan to "leave the family" and embark on a life of Buddhist teachings.[1] Later, he became a patriarch of Donglin Temple (East Forest Temple) at Mount Lushan. His teachings were various, including the vinaya (戒律), meditation (禪法), abhidharma and Prajna or wisdom. Although Huiyuan did not take the initiative in establishing the relations with the secular world, he had contacts with court and gentry families. Huiyuan was on two occasions invited by the dictator Huan Xuan to take part in the discussions about the status of the clergy and Huiyuan defended the independence of the clergy. Members of the cultured classes came to live on Mount Lu as Huiyuan's lay disciples to take part in the religious life. Besides his teaching and interaction with lay followers of the Buddhist faith, he also upheld a learned correspondence with the monk Kumarajiva.[2]
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