To evaluate the laparoscopic operation for early ovarian malignant tumor with low risk. Ten patients with ovarian malignant tumor who underwent laparoscopic total hysterectomy, pelvic lymph nodes dissection, bilateral adnexectomy, ovarian aortic and vein high ligation, omentectomy, and additional appendectomy. Eleven patients with the same diagnosi...


... However, no clear morphologic changes were found between control cells and Snail-knockdown cells. 16 Although the Ecadherin expression could not be detected in these cells at protein lever (Fig. 1a), but there is significant upregulation of E-cadherin mRNA after knockdown expression of Snail (Fig. 1b), indicating that Snail is required to suppress the expression of E-cadherin in ovarian cancer. In addition, expression of fibronectin, one of the mesenchymal markers, was greatly downregulated in the stable antisense-Snail-transfected cells when compared with the parental cells (Fig. 1b). ...
School of Marxism The School of Marxism, established in 2009, including 6 Teaching and Research Department and 2 researching centers. Offers the two and half year MP with about 20 students; the PhD program with 30 students in residence. Main researching directions are Theory of Marxism, Study of Marxism in China, Education in Ideology and Politics, Foreign Marxism. The school responsible for the teaching and management of the ideological and Political Theory Course.

Objective: To investigate the expression of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) and the relationship with cell cycle profiles in ovarian cancer SK-OV-3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. Expression of P-gp and MRP was detected with flow cyt...
Objective To assess the effect of 17β-estradiol(E2) on cell proliferation, cell invasiveness and its regulation of MTA3, Snail and matrix metalloproteinase 2 (MMP-2) expression in the ovarian clear cell adenocarcinoma cell line ES2, and to further investigate the mechanism involved. Methods We first investigated expression of ERα, ERβ, PR and E-cad...
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif...
To study the expression of VEGF, KDR, MMP-1, and its transcription factor Ets-1 on the interstitial neovasculogenesis in human cervical carcinoma on molecular level, which may provide further theoretic bases on judgement of prognosis and explain interregularity between neovasculagenetic factors. VEGF, KDR, MMP-1, and Ets-1 were detected in 87 cervi...

... Temserolimus was FDA approved for the treatment of advanced renal cell carcinoma in 2007 and is currently being evaluated in several clinical trials for its use in the treatment of gynecologic malignancies, including ovarian carcinoma.[28] Cell culture studies [10,293031 and mouse models323334353637 also suggested that PI3K pathway inhibitors are efficient in suppressing ovarian cancer cell growth. We analyzed the effect of the PI3K, AKT and mTORC1 inhibitors LY294002, SH-6 and rapamycin, respectively, on ovarian cancer cell growth using established cell lines and fresh human tumor tissue. ...
Objective To assess the effect of 17β-estradiol(E2) on cell proliferation, cell invasiveness and its regulation of MTA3, Snail and matrix metalloproteinase 2 (MMP-2) expression in the ovarian clear cell adenocarcinoma cell line ES2, and to further investigate the mechanism involved. Methods We first investigated expression of ERα, ERβ, PR and E-cad...
The Joint Institute has tuition-waived student exchange agreements with a several leading universities as well as various programs with the university of Michigan. If your university is a member of the Global E³ Network or you believe that your institution has an exchange agreement with Shanghai Jiao Tong University (SJTU), please contact your international programs office for information on how to apply.

Huang Yaoshi is married to Feng Heng and has six apprentices. He has scores of servants on his island, who are deaf and mute. Rumours in the jianghu say that he intentionally disabled them, but in fact, they were already mute and deaf before they became his servants. He recruited them as his servants to relieve them from the social stigma of their impairments so that they can enjoy a better life on his island. However, he does not wish to promote an image of himself as a kind and compassionate person so he spread those negative rumours about himself. Only his family and apprentices know the truth.
Up to 30% of failure rate in endometrial hyperplasia patients treated by progestin urges more detailed understanding of the mechanisms involved in progestin resistance. Survivin is a key regulator in the antiapoptotic network, and overexpression of survivin has been reported in endometrial hyperplasia and cancer. This study investigated the role of...
... Previous studies have discovered high IKCal expressions in endometrial carcinoma, breast cancer, urinary bladder carcinoma, colon cancer, and glioblastoma cells. [4][5][6][7] This study demonstrated the close relationship between the Ca 2+ -activated K + channel and cervical cancer. [8,9] This study utilized the K + -channel blocker clotrimazole (CLT) and small hairpin ribonucleic acid (RNA) to explore the role played by (and the effect of) IKCal in the proliferation of HeLa cells. ...

IQGAP1 is a scaffolding protein and overexpressed in many human tumors, including ovarian cancer. However, the contribution of IQGAP1 to invasive properties of ovarian cancer cells remains unknown. Here, we investigated the effect of IQGAP1-specific short hairpin RNA (shRNA) expressing plasmids on metastatic potential of ovarian cancer HO-8910PM ce...


To assess the clinical features and prognostic factors of malignant ovarian teratoma. Eighty-four patients with malignant ovarian teratoma between 1954 and 2001 were studied retrospectively. All patients were treated with surgery, the mid-period of follow-up was 146 months. Patient characteristics, surgical therapy, pathologic diagnosis, histologic...

USC-SJTU Institute of Cultural and Creative Industry USC-SJTU Institute of Cultural and Creative Industry (ICCI) is jointly established by Shanghai Jiao Tong University (SJTU) and University of Southern California (USC). With supports from all aspects of the society, ICCI aims to develop itself into a pilot of international collaboration in the field of cultural and creative industry.When culture leads, creativity triumphs. Located in the economic and financial center of China and taking the revitalization of the country and the nation as its own mission, Shanghai Jiao Tong University has cultivated numerous elites in politics, science, industries and arts, and has made great contributions to the country’s economics, science and technology, arts, and health care since founded in 1896. There are a number of famous alumni such as Li Shutong (a master of culture and arts), Lu Yan (a Chinese Hollywood Actress), Hong Shen (a dramatist), and Zhu Qizhan (a famous painter). This manifests the great contribution SJTU has made to the culture and creative industry. University of Southern California is located in Los Angeles, the cultural capital of the world. It has enjoyed a long-lasting high reputation for cultivating a large number of elites in the cultural and creative industry.


Background: Insulin resistance (IR) has been well studied in the initiation and development of endometrial endometrioid carcinoma (EEC). As yet, it has been largely neglected for estrogen sensitivity in local endometrium in hyperinsulinemia-induced systemic microenvironment. The aim of this study was to investigate the role of insulin in regulating...
In Chinese grammar de hua (的话) is a very common and important word. It is used either alone or in combination with other words to express “if”. De hua is probably the most common way to express “if” in Chinese, in fact. Because of this, all students of Mandarin Chinese should be familiar with how to use this word, and that's what this guide is for.
To study the expression of glucose transporter-1 (GLUT1) and its correlation with basic fibroblast growth factor (bFGF) and proliferating cell nuclear antigen (PCNA) in epithelial ovarian neoplasm. Streptavidin-peroxidase complex technique was used to examine the expression of GLUT1, bFGF and PCNA protein in six cases of normal ovarian tissue, 20 c...
To observe whether endothelial cell (EC) progenitors (CD(34)(+)-positive mononuclear cells) participated in neovasculogenesis of ovarian epithelial carcinoma through in vitro and in vivo experiments, and to explore the mechanism of tumor neovasculogenesis. CD(34)(+)-positive mononuclear cells were isolated from peripheral blood of ovarian epithelia...
The university's School of International Education is located here, where a large number of international students take classes throughout the academic year (however, most international students that take degree courses are in Minhang campus). The campus still houses a variety of scientific research institutions, State Key Laboratory of Ocean Engineering for instance, although most moved to the new campus since 1987.
To study the expression of intermediate-conductance-Ca(2+)-activated K(+) (IKCa1) channels in endometrial cancer and its role in regulating proliferation of endometrial cancer cells. Western blot and RT-PCR were used to examine the expression of IKCa1 channels in 13 normal endometrial specimens and 25 endometrial cancer specimens; and RNA interfere...

Ovarian epithelial cancer is the leading cause of death among gynecological malignancies. FSH may increase the risk of ovarian malignancy and play an important role in ovarian carcinogenesis. Our previous studies showed that FSH increases the expression of VEGF through survivin. In this study, the function and mechanism of FSH in ovarian cancer wer...
Objective: The transcription factor Snail, which is implicated in the triggering of epithelial-mesenchymal transitions (EMT), plays an important role in adhesion, invasion and metastasis of tumor cells. In the present study, we assessed 17beta-Estradiol (E2)'s effect on Snail, E-cadherin and MMP-2 expression of epithelial ovarian cancer cell line...
Since 2003, Shanghai Jiao Tong University has produced the Academic Ranking of World Universities[24] which analyzes the top universities in the world on quality of faculty (40%), research output (40%), quality of education (10%) and performance vs. size (10%).[25] Its ranking is exclusively of research universities, mainly in the empirical sciences.

School of Electronic, Information and Electrical Engineering The School of Electronic Information and Electrical Engineering (SEIEE) at Shanghai Jiao Tong University (SJTU) was established in 2001, with its glorious history traced back to 1908 when the discipline of Electric Machines was founded. With a century-long history of reputation in research and education, SEIEE is crowned as “the Cradle of Chinese Electrical Engineers”. The school now has 12 departments and principal units including the Department of Electrical Engineering, the Department of Automation, the Department of Computer Science and Engineering, the Department of Electronic Engineering, the Department of Instrument Science and Engineering, the Department of Micro-Nano Electronics, the School of Cyber Security, the School of Software, the Academy of Information Technology and Electrical Engineering, the Center for Advanced Electronic Materials and Devices, the Center for Teaching and Learning Development, and the Cooperative Medianet Innovation Center.
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