To evaluate the therapeutic efficacies of preserving fertility treatment in patients with early cervical cancer. Sixteen patients with early cervical cancer treated by laparoscopic vaginal radical trachelectomy and pre- or postoperative chemotherapy were analyzed retrospectively, focusing on the treatment indication and management of high risk pati...
School of Humanities The School of Humanities, composed of three Departments and two Centers, offers two undergraduate programs, three master degree programs, one professional master degree program, and two Ph. D programs in four academic categoriess covering Chinese Language and Literature, History, Philosophy, and Art. The School has 1551 students and 141 full-time faculty members, among which 28 are professors, 3 are Zhiyuan chair professors, 1 is Jingyu Chair professor, and 6 are distinguished professors, 1 is elected in Shanghai Thousand Talents Program, 2 are involved in the New Century Excellent Talent Support Project of the MOE, China and 24 teachers hold overseas doctoral degrees. The School offers 40% of the core courses for liberal education in the whole university and undertaks a total number of 74 projects at the ministrial and provincial level or above, among which 41 are programs supported by the national social science foundation of China.

Golgi phosphoprotein 3 (GOLPH3), a newly recognized oncogene, is associated with tumor growth, metastasis, and poor prognosis in several types of cancer. However, its biological role and underlying mechanism in epithelial ovarian cancer (EOC) remain poorly understood. Here, we found that GOLPH3 was overexpressed in EOC tissues and cell lines. This...

School of Mathematical Sciences The School of Mathematical Sciences (SMS) enjoys a rich history dating back to the establishment of Department of Mathematics in 1928, 32 years after the founding of the university. One evidence of its place in modern mathematics in China is that the first Congress of the Chinese Mathematical Society was held in 1935 at SJTU. In 2014, the Department of Mathematics was selected by the central government as one of the first four Model Schools for Internationalization, which encourages us to be more internationalization in its practices, vision and outlook. With the growth in size, it was reorganized into the School of Mathematical Sciences in December 2015. With more than 100 faculties members, the school now consists of 3 departments (Mathematics, Applied and Computational Mathematics, and Statistics) and 1 center (Research Center for Mathematics Education).


Department of Physical Education Established in 1986, the Physical Education Department of Shanghai Jiao Tong University is directly affiliated to the university. After more than 30 years of development, it has one first-level discipline authorized to offer master degree. There are 82 faculty members including 5 professors, 2 chair professors and 1 academic leader. It has been continuously awarded the "Presedent Cup" for seven times in national university games. The Department focuses on talent cultivation since the very beginning. By adhering to the "four combinations", the department will take teaching as the core, mass sport as the foundation, competition as the highlight and scientific research as the driving force. It will work actively to build the first-level platform with the characteristics of SJTU to cultivate talents by physical education.
Huiyuan began studying the Zhuangzi and Laozi at a young age, as well as the teachings of Confucius. However, at the age of 21 he was converted in Hebei Province by the Buddhist Dao An, who was a Chinese disciple of a Kuchan missionary. Hearing the sermons of Dao An convinced Huiyuan to "leave the family" and embark on a life of Buddhist teachings.[1] Later, he became a patriarch of Donglin Temple (East Forest Temple) at Mount Lushan. His teachings were various, including the vinaya (戒律), meditation (禪法), abhidharma and Prajna or wisdom. Although Huiyuan did not take the initiative in establishing the relations with the secular world, he had contacts with court and gentry families. Huiyuan was on two occasions invited by the dictator Huan Xuan to take part in the discussions about the status of the clergy and Huiyuan defended the independence of the clergy. Members of the cultured classes came to live on Mount Lu as Huiyuan's lay disciples to take part in the religious life. Besides his teaching and interaction with lay followers of the Buddhist faith, he also upheld a learned correspondence with the monk Kumarajiva.[2]

... Mediator complex subunit 19 (MED19) is a member of the mediator that has a key role in the activation and repression of signal transduction or the regulation of transcription in carcinomas ( Casamassimi and Napoli, 2007;Sun et al, 2011). Accumulating evidence has shown that MED19 has important roles in cancer cell proliferation and tumorigenesis, and suppression of MED19 expression induces inhibition of cell proliferation and tumorigenesis in several different tumour types including lung cancer, pancreatic cancer, ovarian cancer and breast cancer ( Liu et al, 2012;Wei et al, 2015). Then we speculated that miR-214 played tumorigenic role by its target MED19 in CRC. ...
Neovascularization is essential for tumor growth and metastasis. An adequate vasculature feeds tumor growth and enhances the potential of metastasis. For many years, tumor vessels were thought to be lined exclusively by endothelial cells (ECs). However, therapeutic benefits from the promising antiangiogenic strategy targeting genetically stable ECs...
To investigate the inhibitory effect of the mammalian target of rapamycin (mTOR) inhibitor, sirolimus on expression of hypoxia-inducible factor (HIF)1alpha protein and growth of ovarian carcinoma in an athymic mouse xenogeneic transplant model of ovarian cancer. Four groups of female nude mice were inoculated subcutaneously with SKOV3 cells. After...
Purpose: It has previously been shown that follicle-stimulating hormone (FSH) and its receptor contribute to epithelial ovarian cancer (EOC) development. Epithelial-mesenchymal transition (EMT) is the early event of metastasis in cancer. Therefore, the aim of this study was to investigate the roles of FSH and the FSH receptor (FSHR) in EMT of EOC....
Human embryonic stem (hES) cells are able to give rise to a variety of cell lineages under specific culture condition. An effective strategy for stable genetic modification in hES cells may provide a powerful tool for study of human embryogenesis and cell-based therapies. However, gene silences are documented in hES cells. In current study, we inve...
... Interestingly, estradiol may play a dual role in modulating NRF2 activity. On the one hand, its metabolites activate NRF2 via the generation of reactive oxygen species (ROS) (independent of the ER) [29]. While recent studies demonstrated that estradiol leads to an activation of NRF2 in a wide range of cell types [30,31], the estradiol effect was only noted on protein and not on mRNA levels, suggesting that the main effect of estradiol is based on NRF2 protein stabilization [32]. ...
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