Sun Min, wife of a Chinese businessman, was found guilty of insider trading in Huiyuan shares by the Market Misconduct Tribunal in Hong Kong. The businessman, Mo Feng, and Sun purchased 8.61 million shares in the company between 30 July and 29 August 2008, at between HK$3.78 and 4.66 (US$0.48–$0.60), then resold their shares HK$10.24–$11.12 (US$1.21–$1.43) each on 3–4 Sept. 2008, after Huiyuan's stock price had surged after the proposed takeover was announced. A profit of HK$55.1 million (US$7.09 million) was made from the trade.[9] Sun was convicted of having dealt in 3.13 million Huiyuan shares in August 2008[10] and was fined HK$20 million (US$2.56 million), the largest ever imposed for the crime in the territory.[11]
To investigate the effects of sulindac metabolites on proliferation and apoptosis in the human umbilical vein endothelial cell line ECV304 in vitro. The proliferation profile of ECV304 was determined by methyl thiazolyl tetrazolium (MTT) method. Cell cycle distribution, apoptosis and the ultrastructure of ECV304 were detected by flow cytometry (FCM...
The pathogenesis of preeclampsia is unclear but is thought to be related to shallow trophoblast invasion. An invasive phenotype is acquired by trophoblasts through the process of epithelial-mesenchymal transition (EMT). We proposed that EMT in trophoblasts is deregulated in preeclampsia. The homeobox gene DLX4 plays an important role in epithelial-...
To compare the therapeutic and toxic profile of topotecan given intraperitoneally with intravenously in human ovarian cancer xenografted into athymic nude mice. Eighty female Balb-c/nu-nu mice were randomized assigned into eight groups (n=10). Xenografts resulted from intramesentery injection of cultured human ovarian cancer cells SKOV3 in athymic...
School of Physics and Astronomy The physics department of Shanghai Jiao Tong University was initially established in 1928, and was one of the earliest physics programs in China. Starting from 2007, the University made a strategic decision to rebuild a first-class physics program and started to invest newly on several subfields of physics, such as particle and nuclear physics, laser & plasma physics. After further incorporating astronomy and astrophysics in the year of 2016, the department was renamed the School of Physics and Astronomy. The School currently has now sixty-six full professors and forty-three distinguished research fellows which is equivalent to tenure track assistant professors in the US system. It has seven research institutes. The School sets up its mission to meet the Chinese national strategic demands in physical sciences and related interdisciplinary fields. It strives to establish a world-class research-education center of physical sciences that aim to solve scientific problems of substantial importance and to cultivate next generation of leading physicists. At present, the School covers two first-class disciplines of physics and astronomy. It has become one of the three most comprehensive physics schools in C-9 group, one of the four physics schools who boast national collaborative innovation research centers, and one of the first batch of six pilot institutes in Shanghai Jiao Tong University to build the world-class universities. It is acknowledged as one of the most competitive, fastest-growing, and comprehensive physics colleges in China.
Zhiyuan College The Zhiyuan College, established in January 2010, offers “Zhiyuan Honors Program” to the top 5% SJTU undergraduates. Today, Zhiyuan has seven undergraduate programs: Mathematics, Physics, Life Science, Computer Science, Chemistry, Engineering and Biomedical Science. Aiming at cultivating top-notch talents into international academic masters, Zhiyuan College has recruited a group of eminent scholars from around the world to build first-class faculty team. Each year, Zhiyuan admits 350 students and there are 433 alumni worldwide currently, 90% of whom are pursuing further studies at top domestic and international universities and institutions. In addition to having a strong academic record, students who show a strong interest and the potential to pursue a research career are selected. In 2014, the talent training model of Zhiyuan College won the first-class award of “National Teaching Achievement Award”; and in 2016, “Zhiyuan Model” won “Cultivating Curiosity Award” and “Natural Sciences Award” of “Reimagine Education 2016”, which is jointly hosted by Wharton School of the University of Pennsylvania and QS—international institution for world university rankings on education.
Jiaozuo (Chinese: 焦作; pinyin: Jiāozuò [tɕjáu.tswô]; postal: Tsiaotso) is a prefecture-level city in northern Henan province, China. Sitting on the northern bank of the Yellow River, it borders the provincial capital of Zhengzhou to the south, Xinxiang to the east, Jiyuan to the west, Luoyang to the southwest, and the province of Shanxi to the north.Jiaozuo is one of the core cities of the Central Plains urban agglomeration and a regional central city in the Jin-Yu border area.link
Department of Physical Education Established in 1986, the Physical Education Department of Shanghai Jiao Tong University is directly affiliated to the university. After more than 30 years of development, it has one first-level discipline authorized to offer master degree. There are 82 faculty members including 5 professors, 2 chair professors and 1 academic leader. It has been continuously awarded the "Presedent Cup" for seven times in national university games. The Department focuses on talent cultivation since the very beginning. By adhering to the "four combinations", the department will take teaching as the core, mass sport as the foundation, competition as the highlight and scientific research as the driving force. It will work actively to build the first-level platform with the characteristics of SJTU to cultivate talents by physical education.
Chemotherapy-resistance is the major obstacle for endometrial carcinoma patient administration. Accumulated evidences indicate that metformin sensitizes cancers from several different sites to chemotherapy drugs and reverses progestin resistance in endometrial cancer. Our group has demonstrated that metformin reverses progestin resistance and enhan...
p53 is the most commonly mutated tumor suppressor gene in human cancers. In addition to the loss of tumor suppression function and exertion of dominant-negative effects over the remaining wild-type protein, several p53 mutants can gain novel oncogenic functions (gain-of-function, GOF) that actively regulate cancer development and progression. In hu...
School of Biomedical Engineering The School of Biomedical Engineering (BME) aims to satisfy the major needs of global development and meet the demand for interdisciplinary programs between medicine, science, and engineering. Based on the current frontiers of international research, major national needs, interdisciplinary programs, and the existing foundation of SJTU, BME consists the following six disciplines: Biomedical Instrumentation, Neuroscience and Engineering, Medical Imaging & Informatics, Nano-biomaterials, Systems Biology & Medicine, and Biological Sciences & Diseases. BME has been dedicated in cultivating high-level research, development, and management talents that are internationally competitive in the field of biomedical engineering.
KoGuan Law School Legal education at Shanghai Jiao Tong University can be traced back to special and political classes during the period of Nanyang College in September 1901. However, it was interrupted during the education reform in 1950s until the Law School was re-established on June 8 2002. The law School received the new title “KoGuan School of Law” in 2008 in memorial of the generous donation of Professor Leo KoGuan. KoGuan School of Law has a strong, well-structured and international team of faculty, including 65 full-time faculty members. A variety of research centers within the law school has produced high quality scholarship covering a wide range of fields and disciplines, from constitutional law to law and society, from maritime law to competition law, etc. KoGuan School of Law has explored its own style of educating a new generation of law students and future jurists, and established its own reputation in both academic and practical circles. For the time being, it offers a full-scale legal education system including LLB, LLM, JM, and PhD programs.
To explore possibility of vasculogenic mimicry induced by hypoxia and the inhibitive effect by sirolimus in epithelial ovarian carcinoma in vitro. Based on three-dimensional cell culture system developed by Matrigel, ovarian cell lines SKOV3 and ES2 were induced under conditions of hypoxia, hypoxia added with sirolimus and no-hypoxia, respectively....
Jiaozuo is noted for its blast furnaces and machine construction industries. The total GDP of the city in 2017 was 234.28 billion yuan, an increase of 7.4% over the previous year. Among them, the added value of the primary industry was 13.733 billion yuan, up 4.6%; the added value of the secondary industry was 13.841 billion yuan, up 6.7%; the added value of the tertiary industry was 81.143 billion yuan, up 9.1%. The per capita GDP reached 65,936 yuan. The three industrial structures changed from 6.4:59.3:34.3 of 2016 to 5.9:59.5:34.6.link
... This process takes place at the beginning of vascular development and during post-natal life (11,22). Myeloid cells and EPCs are recruited by pro-angiogenic or pro-inflammatory factors to the tumor vascular bed, where they differentiate into ECs and give place to neovasculature (23)(24)(25). Vasculogenesis has a modest impact on tumor vascularization when the angiogenesis pathway is active, however, it is recognized as an important rescue process when this pathway is blocked (10,26). For instance, when angiogenesis is inhibited after anti-angiogenic treatment or radiotherapy, myeloid cells, and EPCs are recruited by the stroma-derived factor 1 (SDF-1) in response to an increased level of hypoxia-inducible factor 1α (HIF-1α) (10,26). ...
To establish a sprouting embryoid body model mimicking early embryonic vasculogenesis in human embryo. Human embryonic stem were (hESCs) were cultured on the mouse embryo fibroblasts and then were induced to differentiate to form three-dimensional EB. The hEBs were cultured in media containing various angiogenesis-related factors: vascular endothel...
In the same year, Feng Heng was pregnant with Huang Rong. When she learnt that the copy she wrote had been stolen, she attempted to write another from memory for her husband. However, the stress was too much for her to bear so she died shortly after giving birth to Huang Rong. Huang Yaoshi was deeply tramautised by the loss of his wife and driven to near-insanity. He vented his anger on his other four apprentices (Qu Lingfeng, Lu Chengfeng, Wu Mianfeng and Feng Mofeng) by crippling them and banishing them from his island.
A few highly aggressive and malignant tumor cells could acquire identities by turning on genes expressed by endothelial cells and recruit blood vessels to sustain tumor growth. Hypoxia was reported recently to play an essential role in these events. These 'plastic' tumor-cell phenotypes and the exact mechanism driving transendothelial differentiati...
KoGuan Law School Legal education at Shanghai Jiao Tong University can be traced back to special and political classes during the period of Nanyang College in September 1901. However, it was interrupted during the education reform in 1950s until the Law School was re-established on June 8 2002. The law School received the new title “KoGuan School of Law” in 2008 in memorial of the generous donation of Professor Leo KoGuan. KoGuan School of Law has a strong, well-structured and international team of faculty, including 65 full-time faculty members. A variety of research centers within the law school has produced high quality scholarship covering a wide range of fields and disciplines, from constitutional law to law and society, from maritime law to competition law, etc. KoGuan School of Law has explored its own style of educating a new generation of law students and future jurists, and established its own reputation in both academic and practical circles. For the time being, it offers a full-scale legal education system including LLB, LLM, JM, and PhD programs.
To identify new genetic risk factors for cervical cancer, we conducted a genome-wide association study in the Han Chinese population. The initial discovery set included 1,364 individuals with cervical cancer (cases) and 3,028 female controls, and we selected a 'stringently matched samples' subset (829 cases and 990 controls) from the discovery set...
... [9,25] Overall, the main reasons reported contributing to the psychosocial burden among women (anxious, fearful, self-blame, powerlessness, disbelief, depression, and anger) in this domain were lack of understanding of abnormal Pap smear results and higher perceived risk of developing cervical cancer which also have negative impact on perception of self. [10,11,26] Domain 3: Worry about human papillomavirus infectivity Women of reproductive age were found to have a significantly higher mean score not only in general but also in both individual items of this domain " worry about HPV infectivity " compared to a menopausal group of women. Our results were quite similar to the study conducted in the United States which reported that women with abnormal Pap smear results were distressed due to a sense of shame or guilt when they came to know that these cervical changes are associated with HPV and which is a sexually transmitted infection. ...
Our previous studies have showed that Gankyrin expression is correlated with a malignant phenotype in endometrial carcinoma. Here, we investigated the possible role of Gankyrin in cervical disease. The increasing protein level of Gankyrin was observed in high-grade cervical intraepithelial neoplasia and carcinoma compared with benign cervical tissu...
FKBP14 belongs to the family of FK506-binding proteins (FKBPs). Altered expression of FKBPs has been reported in several malignancies. This study aimed to reveal the expression profile of FKBP14 in ovarian cancer and evaluate whether FKBP14 is a molecular target for cancer therapy. We found that the FKBP14 mRNA level was significantly higher in ova...
Our previous study revealed that estrogen regulates nm23-H1 expression thus promoting cell migration-invasion via activating PIK3/Akt pathway. In this study, we explored the effect of hormone on hypoxia-inducible factor-1 (HIF-1alpha), a key factor in cancer invasion and metastasis, via activation of Akt signaling transduction pathway. We treated t...

Neovascularization is essential for tumor growth and metastasis. An adequate vasculature feeds tumor growth and enhances the potential of metastasis. For many years, tumor vessels were thought to be lined exclusively by endothelial cells (ECs). However, therapeutic benefits from the promising antiangiogenic strategy targeting genetically stable ECs...
Gankyrin has been implicated in the formation of multiple cancer types, although its roles in estrogen-driven endometrial carcinoma remain unclarified. We evaluated the expression of Gankyrin in endometrial tissues and further explored its roles in estrogen-driven and GPR30-mediated endometrial cancer cell proliferation. Gankyrin was overexpressed...
Most buildings on campus were influenced by American architecture, while the main gate, which was built in 1935, is of traditional Chinese style reflecting the University's earlier status as the "Imperial Polytechnic College". The approaches to the main gate were via a series of marble bridges, similar to, although smaller than, those built in front of Tiananmen. However, recent road expansions have demolished the river as well as most of bridges. A copy of this famous gate scene have been built on the east of Minhang campus.
A cultural events package for the international student community at JI, including excursions into the environs of Shanghai, martial arts, Chinese cuisine and similar classes as well as cultural and social events is strongly recommended to be taken by all students at JI. The cost for the whole package is 2,500 RMB and must be paid in advance of coming to JI.

To observe whether endothelial cell (EC) progenitors (CD(34)(+)-positive mononuclear cells) participated in neovasculogenesis of ovarian epithelial carcinoma through in vitro and in vivo experiments, and to explore the mechanism of tumor neovasculogenesis. CD(34)(+)-positive mononuclear cells were isolated from peripheral blood of ovarian epithelia...
Luteinizing hormone (LH) plays an important role in the development of ovarian cancer, and has been shown to inhibit apoptosis in ovarian cancer cells. Similarly, survivin is a molecule that has been shown to inhibit apoptosis in other types of cancer. Therefore, the aim of this study was to determine whether survivin can be induced by LH in ovaria...
Human homeobox gene (HOX) A10 is a homeobox allotype gene of the HOXA family in the HOX family. Human homeobox gene A10 may play an important role in cancer development. However, the role of HOXA10 in the carcinogenesis of ovarian clear cell adenocarcinoma (OCCA) has not been established. We have evaluated the prognostic significance of HOXA10 expr...

UM-SJTU Joint Institute The UM-SJTU Joint Institute (JI) was jointly established in 2006 by two premier universities, the University of Michigan and Shanghai Jiao Tong University. The mission of JI is to build a world-class educational and research institute in China and foster future researchers and leaders with a global perspective. Abiding by the philosophy of “Internationalization, Interdisciplinary, Innovation, and Quality”, JI adopts curriculums blending the unique features of the two founding universities. Both of its undergraduate majors, Mechanical Engineering (ME) and Electrical & Computer Engineering (ECE), achieved the world’s most authoritative ABET accreditation. All courses are taught in English by world-class faculty recruited from global leading universities in the U.S. and other developed countries. Many are winners of prestigious awards such as Yangtze Scholar, 1000-talent Scholars, New Century Talents, Pujiang Scholars, and Shanghai Magnolia Gold and Silver Awards. JI has won many awards for higher education innovation, including the “Model of Chinese Higher Education Reform” from the Chinese State Council and the “Andrew Heiskell Award for Innovation in Higher Education” from the Institute of International Education, one of the most prestigious awards in international education.
In June 1962, he was appointed Communist Party Secretary of Weishi County. In December, he became the Second Communist Party Secretary of Lankao County. This region had declined into poverty and ignorance. The county had long been plagued by dust storms, waterlogging, and alkaline lands.[3] Jiao Yulu devoted his energies to fight economic backwardness. He mobilized the local residents to contend with the poor natural conditions. Due to years of toil, Jiao Yulu broke down from constant overwork and he was diagnosed with liver cancer. But he continued his struggle against natural disasters. On May 14, 1964, he died of liver cancer, aged 42.[3]
Endometrial cancer is a common gynecologic malignancy among women. The molecular mechanisms involved in the progression of endometrial cancer are unclear, which has hampered the development of an effective treatment. Survivin, a newly identified member of the inhibitor of apoptosis (IAP) family, regulates 2 critical processes in neoplastic transfor...
To express tumor necrosis factor related apoptosis inducing ligand (TRAIL) protein using endothelial progenitor cell (EPC) and observe antitumor activity of secreted TRAIL in cell culture supernatant. EPC were isolated by immunomagnetic sorting. Human TRAIL plasmid was transfected into EPC by lipofectamine 2000. The cell culture supernatant was har...
In 1945, after the defeat of the Japanese in the Second World War, he returned his hometown and joined a militia. He once took part in the battle of liberating Boshan District. Jiao Yulu joined the Communist Party of China in January 1946, and he soon was transferred to Bohai, Shandong and appointed a group leader of the Land Reform movement. By late Chinese Civil War, he worked in Weishi County, Henan province until 1951. In June 1953, he was transferred to Luoyang Mine Machine Manufacturing Plant and worked there until 1962.
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