Ovarian carcinoma is leading cause of death in gynecologic malignancies. The survival rate cannot be improved after routine surgery, chemotherapy, and radiotherapy. Therefore biotherapy becomes the fourth treatment pattern for ovarian carcinoma. Adequate experimental models for the development of biologic therapeutic strategies are needed. Our purp...
Progestin resistance is the main obstacle to successful conservative therapy in young endometrial cancer patients. To investigate the molecular events that lead to progestin resistance and to find a possible way to reverse progestin resistance in endometrial cancer, we established a progestin-resistant Ishikawa cell line by long-term progestin trea...
High levels of gonadotropin are a risk factor for ovarian cancer development. Aberrant gonadotropin levels benefit tumor angiogenesis, but the detailed mechanism is not clear. Therefore, the aim of this study was to investigate the molecular mechanism of high levels of luteinizing hormone (LH) on the promotion of tumor angiogenesis and to outline a...
In 1945, after the defeat of the Japanese in the Second World War, he returned his hometown and joined a militia. He once took part in the battle of liberating Boshan District. Jiao Yulu joined the Communist Party of China in January 1946, and he soon was transferred to Bohai, Shandong and appointed a group leader of the Land Reform movement. By late Chinese Civil War, he worked in Weishi County, Henan province until 1951. In June 1953, he was transferred to Luoyang Mine Machine Manufacturing Plant and worked there until 1962.

China Huiyuan Juice Group Limited (Chinese: 中国汇源果汁集团有限公司; pinyin: Zhōngguó Huìyuán Guǒzhī Jítuán Yǒuxiàn Gōngsī) (SEHK: 1886), established in 1992 and headquartered in Beijing, is the largest privately owned juice producer in China.[1] It is engaged in the manufacture and sales of juice and other beverage products. Its products include fruit juice and vegetable juice, nectars, bottled water, tea, and dairy drinks.[2]
Objective To assess the effect of 17β-estradiol(E2) on cell proliferation, cell invasiveness and its regulation of MTA3, Snail and matrix metalloproteinase 2 (MMP-2) expression in the ovarian clear cell adenocarcinoma cell line ES2, and to further investigate the mechanism involved. Methods We first investigated expression of ERα, ERβ, PR and E-cad...
Huang Yaoshi makes several brief appearances in the sequel. He rescues Cheng Ying from Li Mochou and accepts the child as his student. He develops a special bond with Yang Guo as both of them share the same distaste for the societal norms of their time, and he teaches Yang Guo two of his celebrated skills. Huang Yaoshi also participates in the defence of Xiangyang from Mongol invaders. At the end of the novel, he retains his original title as "Eastern Heretic" of the new "Five Greats" on Mount Hua, alongside Zhou Botong, Yang Guo, Guo Jing and Yideng.
To investigate the involvement of estrogen receptor (ER) beta in the proliferation of ovarian clear cell adenocarcinoma by restoring ERbeta expression in a cell line ES-2. A plasmid with full length ERbeta cDNA, pRSV-ERbeta and its negative vector control pRSV were introduced into ES-2. The cells transfected were named according to the plasmids: ES...
Huang Yaoshi later regrets bitterly for inflicting such a heavy punishment on his innocent apprentices. He sets off to find his daughter, who has left home after quarrelling with her father. He meets Mei Chaofeng at Guiyun Manor on Lake Tai, where Lu Chengfeng has settled down. He agrees that Mei Chaofeng has been duly punished since she has lost her sense of sight and her husband. He forgives her and asks her to find his other apprentices and bring them back to the manor so he can heal their legs. However, he never saw his other apprentices again: Chen Xuanfeng was killed by Guo Jing; Qu Lingfeng was killed by Shi Yanming; Wu Mianfeng died of illness; Feng Mofeng has become a blacksmith and is killed by Jinlun Guoshi in the sequel. Huang Yaoshi later accepts Lu Chengfeng's son, Lu Guanying, and Qu Lingfeng's daughter, Shagu, as his grand-apprentices.
Snail, a key inducer of epithelial-mesenchymal transition (EMT), plays an important role in cancer metastasis. To better understand the role of Snail in the metastasis of ovarian carcinoma, expression of Snail was knocked down by antisense-Snail in the highly metastatic ovarian cancer cell line HO8910PM. Gene array analysis revealed that blocking S...
Snail, a key inducer of epithelial-mesenchymal transition (EMT), plays an important role in cancer metastasis. To better understand the role of Snail in the metastasis of ovarian carcinoma, expression of Snail was knocked down by antisense-Snail in the highly metastatic ovarian cancer cell line HO8910PM. Gene array analysis revealed that blocking S...
School of Media and Design Established in 2002, School of Media and Design (SMD) at Shanghai Jiao Tong University aims at educating a new generation of communication graduates who are not only equipped with critical thinking but also with creative capability. The School consists of four departments: Journalism & Communication, Film & Television, Design, and Cultural Industry & Management. To date, SMD has more than 90 faculty members. About 25% of them earned their doctoral degrees in the U.S., U.K., and other western countries. SMD also hosts more than 700 undergraduates, 300 master students, and 100 doctoral students. There are currently 324 international students in the school. Among them 104 are master or doctoral students who come from 55 countries including the U.S., U.K., France, Australia, Russia, South Korea, Pakistan etc. Many of them graduated from world prestigious universities like Princeton University, University of Chicago, University of South California and University of California-Los Angeles.
Our previous study revealed that estrogen regulates nm23-H1 expression thus promoting cell migration-invasion via activating PIK3/Akt pathway. In this study, we explored the effect of hormone on hypoxia-inducible factor-1 (HIF-1alpha), a key factor in cancer invasion and metastasis, via activation of Akt signaling transduction pathway. We treated t...

Estrogen and progestin are involved in ovarian carcinogenesis. Change in nm23-H1 expression and the PIK3/AKT pathway are involved in carcinogenesis, development, invasion and metastasis of ovarian cancers. Therefore, it is critical to understand the signaling pathways that regulate hormone-induced cell migration and invasion in ovarian cancer. We i...
School of Mechanical Engineering The history of the School of Mechanical Engineering (ME) , Shanghai Jiao Tong University (SJTU) dates back to 1913. The School has the vision of a world-class engineering school committed to high-level education and cutting edge research. It aims to offer the best learning experience to its students, the most rewarding working environment for its faculty and staff as well as the most effective service to industry and society. Among the 334 faculty members, 124 are professors, 152 are associate professors and 58 are assistant professors, and more than 5000 students are learning here. As one of the top Schools of Mechanical Engineering in China, it strives to increase its international competitiveness and global presence through quality teaching, advanced research and close collaboration with leading universities in the world. The alumni from the School, as scientists, engineers, educators, statesmen and entrepreneurs, always make outstanding contributions to the innovation of science and technology, and the development of the society.
To study the expression of glucose transporter-1 (GLUT1) and its correlation with basic fibroblast growth factor (bFGF) and proliferating cell nuclear antigen (PCNA) in epithelial ovarian neoplasm. Streptavidin-peroxidase complex technique was used to examine the expression of GLUT1, bFGF and PCNA protein in six cases of normal ovarian tissue, 20 c...
The pathogenesis of preeclampsia is unclear but is thought to be related to shallow trophoblast invasion. An invasive phenotype is acquired by trophoblasts through the process of epithelial-mesenchymal transition (EMT). We proposed that EMT in trophoblasts is deregulated in preeclampsia. The homeobox gene DLX4 plays an important role in epithelial-...
Objective: This research was carried out to investigate the effectiveness, rationality, and safety of laparotomy management compared with uterine artery embolization (UAE) combined with methotrexate (MTX) for the treatment of deep implantation cesarean scar pregnancy (CSP II). Materials and methods: Data from 29 patients seen between June 2008 and...
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