Human homeobox gene (HOX) A10 is a homeobox allotype gene of the HOXA family in the HOX family. Human homeobox gene A10 may play an important role in cancer development. However, the role of HOXA10 in the carcinogenesis of ovarian clear cell adenocarcinoma (OCCA) has not been established. We have evaluated the prognostic significance of HOXA10 expr...
To investigate the effect of glycogen synthase kinase-3beta (GSK-3beta) on the proliferation of human ovarian cancer cells. Two human ovarian cancer cell lines SKOV3 and ES-2 were analysed for the expression of GSK-3beta and phosphorylated GSK-3beta (pGSK-3beta) by Western blot analysis. Cell growth curve analysis done by cell count was used to inv...
Huang Yaoshi is a loner who harbours unorthodox and heretical views on traditional Chinese rites and social norms. He is the master of Peach Blossom Island. Apart from being a formidable martial artist, he is also versed in other fields such as military strategy, music and divination. His eccentric personality causes him to be feared and shunned by others.
Because the activation of telomerase is a relatively early event in the progression of cervical carcinogenesis, the expression of the human telomerase RNA gene, TERC, has the potential to serve as a biomarker for both the diagnosis and prognosis of cervical neoplasias. In total, 83 research centers participated in the study, and 7786 patients were...
Ovarian cancer is the most lethal malignancy of the female reproductive system with an overall mortality rate of greater than 70%. Our group has demonstrated that Follicle stimulating hormone (FSH) stimulates the proliferation and invasion of ovarian cancer cells, inhibits apoptosis, and facilitates neovascularization by increasing expression of va...
Background: Insulin resistance (IR) has been well studied in the initiation and development of endometrial endometrioid carcinoma (EEC). As yet, it has been largely neglected for estrogen sensitivity in local endometrium in hyperinsulinemia-induced systemic microenvironment. The aim of this study was to investigate the role of insulin in regulating...
School of Medicine SJTUSM was formally approved under the“211 Project” as a state key university for full development in November, 1997. In July, 2005, Shanghai Jiao Tong University and Shanghai Second Medical University merged to form the new Shanghai Jiao Tong University, jointly supported by Shanghai Municipal Government and the Ministry of Education. In November, 2010, SJTUSM became one of the first ten universities jointly supported by the Ministry of Health and the Ministry of Education. The rich historic background of over one hundred years and heroic journey of more than 50 years have eventually brought about a research-oriented medical school with all-round development in medical education, clinical services, and scientific research, as well as other social services, a medical school with outstanding features and distinct advantages, a strong faculty, and remarkable academic achievements. In the new round of evaluating disciplines in degree and graduate programs organized by the Ministry of Education in 2009, clinical medicine of SJTUSM ranked first nationally, and the comprehensive strength of various disciplines belonged to the first echelon of the nation's medical schools.
... ovarian diameter must be ≥ 31 mm. The presence of PFOs was evaluated binary, thereby the visualization of at least one side (unilateral)/individual was considered positive [129] . It has to be recognized that an PFO/ " PCO " is according to Netter (1990) [21] just a " clinical finding similar to splenomegaly or hepatomegaly ; cystic ovaries are found in a multiplicity of states, which have nothing in common etiologically; the clinical management varies and is dependent on the etiology " . ...
To identify new genetic risk factors for cervical cancer, we conducted a genome-wide association study in the Han Chinese population. The initial discovery set included 1,364 individuals with cervical cancer (cases) and 3,028 female controls, and we selected a 'stringently matched samples' subset (829 cases and 990 controls) from the discovery set...
AAeronautics and AstronauticsAgriculture and BiologyAntai College of Economic and ManagementBBiomedical EngineeringCChemistry and Chemical EngineeringChina Europe International Business SchoolChina-UK Low Carbon CollegeEElectronic, Information and Electrical EngineeringEnvironmental Sciences and EngineeringFForeign LanguagesHHumanitiesIInternational and Public AffairsKKoGuan Law SchoolLLife Sciences and BiotechnologyMMarxismMaterials Science and EngineeringMathematical SciencesMechanical Engineering Media and DesignMedicineNNaval Architecture, Ocean and Civil EngineeringPPharmacyPhysical EducationPhysics and AstronomySShanghai Advanced Institute of FinanceSJTU-ParisTech Elite Institute of Technology U UM-SJTU Joint Institute USC-SJTU Institute of Cultural and Creative Industry Z Zhiyuan College
Snail, a key inducer of epithelial-mesenchymal transition (EMT), plays an important role in cancer metastasis. To better understand the role of Snail in the metastasis of ovarian carcinoma, expression of Snail was knocked down by antisense-Snail in the highly metastatic ovarian cancer cell line HO8910PM. Gene array analysis revealed that blocking S...
... Likewise, our network analyses further support the role of these two GalNAc-Ts in modulating EOC tumorigenesis. Indeed major gene nodes with proven implications in EOC tumorigenesis, including VEGF, PI3K, EZH2, IQGAP1, and HOXD10 [34][35][36][37][38], were downregulated upon GALNT3 ablation. Moreover, multiple gene nodes reported to be involved in EOC progression (such as CUL1 EEF2, PTN, UCHL1, CBX5, USP14, and BMI-1 [39][40][41][42][43][44]) were strongly affected by the GALNT3/T6 double KO. ...
In the year 404, Huiyuan wrote a treatise On Why Monks Do Not Bow Down Before Kings (沙門不敬王者論).[4] This book symbolized his efforts to assert the political independence of Buddhist clergy from the courts of monarchic rulers. At the same time, it was a religious and political text that aimed to convince monarchs and Confucian-minded ministers of state that followers of Buddhism were ultimately not subversive. He argued that Buddhists could make good subjects in a kingdom due to their beliefs in retribution of karma and the desire to be reborn in paradise. Despite the Buddhists' reputation of leaving their family behind for a monastic life, Huiyuan stated "those who rejoice in the Way of the Buddha invariably first serve their parents and obey their lords."[1]

School of Chemistry and Chemical Engineering School of Chemistry and Chemical Engineering (SCCE) has a glorious history dating back to 1928. Inspired by the mottos “Prudence, Pragmaticality, Erudition, Innovation” at SCCE, we have been highly successful in the development of academic disciplines, research, and education excellence. After years of efforts, we have so far more than 160 faculty members, among whom there are four academicians of the Chinese Academy of Science, two chair professors supported by the “Thousand Talents Program”, and 11 experts supported by the “Thousand Young Talents Program”; a large number of scholars are supported by the National Science Fund for Distinguished Young Scholars, the “Cheung Kong Scholars Program”, the “National 973 Project”, the “National Science Fund for Outstanding Scholars”, etc. We provide comprehensive education programs including three undergraduate programs, four postgraduate programs(two master and two Ph.D. programs), visiting student programs and post-doctoral programs. With its energetic faculty and various education programs, SCCE has been considered as one of the long-standing educators in the field of chemistry and chemical engineering in China.
Department of Physical Education Established in 1986, the Physical Education Department of Shanghai Jiao Tong University is directly affiliated to the university. After more than 30 years of development, it has one first-level discipline authorized to offer master degree. There are 82 faculty members including 5 professors, 2 chair professors and 1 academic leader. It has been continuously awarded the "Presedent Cup" for seven times in national university games. The Department focuses on talent cultivation since the very beginning. By adhering to the "four combinations", the department will take teaching as the core, mass sport as the foundation, competition as the highlight and scientific research as the driving force. It will work actively to build the first-level platform with the characteristics of SJTU to cultivate talents by physical education.
... In vEDS cells, an ER perturbation was suggested by the abnormal ER distribution of the protein disulfide isomerase enzyme and by reduced expression of FKBP22, an ER resident peptidyl-prolyl cis-trans-ER isomerase involved in the folding of COLLIII triple helix [108,139,140]. Since the perturbed ER redox state may influence the down-regulation of Bcl-2 and the activation of the caspase-dependent apoptosis [141], and FKBP22 can have an anti-apoptotic role acting on the expression of Bcl-2 and caspases [142], this aspect merits further studies in vEDS fibroblasts. ...
Objective: To detect mRNA levels and expression of CD44, CD54, CD29 and E-cadherin (E-cad) and to discuss their relationship with formation and drug resistance of ovarian cancer SKOV3ip1 multicellular aggregates. Methods: Liquid overlay system was employed to obtain multicellular aggregates. mRNA levels and expression of CD44, CD54, CD29 and E-cad...
Human embryonic stem (hES) cells are able to give rise to a variety of cell lineages under specific culture condition. An effective strategy for stable genetic modification in hES cells may provide a powerful tool for study of human embryogenesis and cell-based therapies. However, gene silences are documented in hES cells. In current study, we inve...
ARHI is a Ras-related imprinted gene that inhibits cancer cell growth and motility. ARHI is downregulated in the majority of breast cancers, and loss of its expression is associated with its progression from ductal carcinoma in situ (DCIS) to invasive disease. In ovarian cancer, re-expression of ARHI induces autophagy and leads to autophagic death...
Purpose: It has previously been shown that follicle-stimulating hormone (FSH) and its receptor contribute to epithelial ovarian cancer (EOC) development. Epithelial-mesenchymal transition (EMT) is the early event of metastasis in cancer. Therefore, the aim of this study was to investigate the roles of FSH and the FSH receptor (FSHR) in EMT of EOC....
Huang Yaoshi makes several brief appearances in the sequel. He rescues Cheng Ying from Li Mochou and accepts the child as his student. He develops a special bond with Yang Guo as both of them share the same distaste for the societal norms of their time, and he teaches Yang Guo two of his celebrated skills. Huang Yaoshi also participates in the defence of Xiangyang from Mongol invaders. At the end of the novel, he retains his original title as "Eastern Heretic" of the new "Five Greats" on Mount Hua, alongside Zhou Botong, Yang Guo, Guo Jing and Yideng.
Although glycogen synthase kinase-3 (GSK-3) might act as a tumor suppressor since its inhibition is expected to mimic the activation of Wnt-signaling pathway, GSK-3beta may contribute to NF-kappaB activation in cancer cells leading to increased cancer cell proliferation and survival. Here we report that GSK-3beta activity was involved in the prolif...
In 1896, the Nanyang Public School (南洋公學) was founded in Shanghai by the imperial edict of the Guangxu Emperor, under the Business and Telegraphs Office of the Qing imperial government. Four schools were established: a normal school, a school of foreign studies, a middle school, and a high school. Sheng Xuanhuai, the mandarin who proposed the idea to the Guangxu Emperor, became the first president and is, along with missionary educator John Calvin Ferguson, regarded as the founder of the university.
Huang Yaoshi is a fictional character in the wuxia novel The Legend of the Condor Heroes and its sequel, The Return of the Condor Heroes, by Jin Yong. He is one of the Five Greats of the wulin (martial artists' community) during the Song dynasty, alongside Wang Chongyang, Hong Qigong, Ouyang Feng and Duan Zhixing. He is nicknamed "Eastern Heretic" (東邪) for being an unorthodox radical who behaves as he wishes without showing any regard for formalities or moral ethics.[SheDiao Ch.10] He loathes the dogma of traditional rites in Chinese society and admires only genuine honour and pure love.[SheDiao Ch.10] As such, he is often regarded by his contemporaries as a cultural heretic.[SheDiao Ch.10] His nickname may be translated to "Eastern Evil" because the character Xie (邪) in his nickname also refers to "evil" and "unorthodoxy" in jianghu terminology.
KoGuan Law School Legal education at Shanghai Jiao Tong University can be traced back to special and political classes during the period of Nanyang College in September 1901. However, it was interrupted during the education reform in 1950s until the Law School was re-established on June 8 2002. The law School received the new title “KoGuan School of Law” in 2008 in memorial of the generous donation of Professor Leo KoGuan. KoGuan School of Law has a strong, well-structured and international team of faculty, including 65 full-time faculty members. A variety of research centers within the law school has produced high quality scholarship covering a wide range of fields and disciplines, from constitutional law to law and society, from maritime law to competition law, etc. KoGuan School of Law has explored its own style of educating a new generation of law students and future jurists, and established its own reputation in both academic and practical circles. For the time being, it offers a full-scale legal education system including LLB, LLM, JM, and PhD programs.

Henan Polytechnic University (HPU)[1], with a history of nearly 100 years, is the first mining university in Chinese history. Its former is Jiaozuo Coal Mining School which was established by the British Syndicate Co. Ltd., in 1909. It has changed its names several times in the course of development, namely, FuZhong Coal Mining University, Jiaozuo Private Institute of Technology, North-west Institute of Technology, Jiaozuo National Institute of Technology, Jiaozuo Mining Institute and Jiaozuo Institute of Technology. The University resumed its name of Henan Polytechnic University in 2004. 
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